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Pharmacological Inhibition of LSD1 for Cancer Treatment Journal article
MOLECULES, 2018,Volume: 23,Issue: 12
Authors:  Yang, Guan-Jun;  Lei, Pui-Man;  Wong, Suk-Yu;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite  |  View/Download:15/0  |  Submit date:2019/01/17
Lsd1  Demethylase  Histone  Breast Cancer  Prostate Cancer  Acute Myeloid Leukemia  Cancer Therapy  
Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
Authors:  Yang, Guan-Jun;  Wang, Wanhe;  Mok, Simon Wing Fai;  Wu, Chun;  Law, Betty Yuen Kwan;  Miao, Xiang-Min;  Wu, Ke-Jia;  Zhong, Hai-Jing;  Wong, Chun-Yuen;  Wong, Vincent Kam Wai;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite  |  View/Download:36/0  |  Submit date:2018/10/30
Drug Discovery  Epigenetics  Medicinal Chemistry  Triple-negative Breast Cancer  
Acetaminophen-induced liver injury is attenuated in transgenic fat-1 mice endogenously synthesizing long-chain n-3 fatty acids Journal article
BIOCHEMICAL PHARMACOLOGY, 2018,Volume: 154,Page: 75-88
Authors:  Feng, Ruibing;  Wang, Yang;  Liu, Conghui;  Yan, Chunyan;  Zhang, Hang;  Su, Huanxing;  Kang, Jing X.;  Shang, Chang-Zhen;  Wan, Jim-Bo
Favorite  |  View/Download:21/0  |  Submit date:2018/10/30
Acetaminophen  N-3 Polyunsaturated Fatty Acids  Hepatotoxicity  Jnk  Inflammatory  
A long-lifetime iridium(III) complex for lysosome tracking with high specificity and a large Stokes shift Journal article
JOURNAL OF MATERIALS CHEMISTRY B, 2018,Volume: 6,Issue: 23,Page: 3855-3858
Authors:  Liu, Jin-Biao;  Vellaisamy, Kasipandi;  Li, Guodong;  Yang, Chao;  Wong, Suk-Yu;  Leung, Chung-Hang;  Pu, Shou-Zhi;  Ma, Dik-Lung
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Identification of a rhodium(III) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 20,Page: 2463-2466
Authors:  Yang, Guan-Jun;  Zhong, Hai-Jing;  Ko, Chung-Nga;  Wong, Suk-Yu;  Vellaisamy, Kasipandi;  Ye, Min;  Ma, Dik-Lung;  Leung, Chung-Hang
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Investigation of hypoxia networks in ovarian cancer via bioinformatics analysis Journal article
JOURNAL OF OVARIAN RESEARCH, 2018,Volume: 11
Authors:  Zhang, Ke;  Kong, Xiangjun;  Feng, Guangde;  Xiang, Wei;  Chen, Long;  Yang, Fang;  Cao, Chunyu;  Ding, Yifei;  Chen, Hang;  Chu, Mingxing;  Wang, Pingqing;  Zhang, Baoyun
Favorite  |  View/Download:24/0  |  Submit date:2018/10/30
Ovarian cancer  Bioinformatics analyses  ErbB signaling pathway  Molecular mechanism  Hypoxia  
Small Molecule Pin1 Inhibitor Blocking NF-B Signaling in Prostate Cancer Cells Journal article
CHEMISTRY-AN ASIAN JOURNAL, 2018,Volume: 13,Issue: 3,Page: 275-279
Authors:  Wu, Ke-Jia;  Zhong, Hai-Jing;  Yang, Guanjun;  Wu, Chun;  Huang, Jie-Min;  Li, Guodong;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Enzymes  Natural Products  Pin1  Protein-protein Interactions  Virtual Screening  
A dual-functional luminescent probe for imaging H2S in living zebrafish and discrimination hypoxic cells from normoxic cells Journal article
SENSORS AND ACTUATORS B-CHEMICAL, 2018,Volume: 255,Page: 1953-1959
Authors:  Wang, Wanhe;  Wu, Chun;  Yang, Chao;  Li, Guodong;  Han, Quan-Bin;  Li, Shengnan;  Lee, Simon Ming-Yuen;  Leung, Chung-Hang;  Ma, Dik-Lung
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
Hydrogen Sulfide  Iridium(Iii) Complex  Sensor  Luminescence  
TiO2 nanowire-templated hierarchical nanowire network as water-repelling coating Journal article
ROYAL SOCIETY OPEN SCIENCE, 2017,Volume: 4,Issue: 12
Authors:  Hang, Tian;  Chen, Hui-Jiuan;  Xiao, Shuai;  Yang, Chengduan;  Chen, Meiwan;  Tao, Jun;  Shieh, Han-Ping;  Yang, Bo-Ru;  Liu, Chuan;  Xie, Xi
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
micro-nanoscale structure  hierarchical nanowires  self-cleaning surfaces  superhydrophobic coatings  nanowire thin film  
Luminescent Strategies for Label-Free G-Quadruplex-Based Enzyme Activity Sensing Journal article
CHEMICAL RECORD, 2017,Volume: 17,Issue: 11,Page: 1135-1145
Authors:  Ma, Dik-Lung;  Dong, Zhen-Zhen;  Vellaisamy, Kasipandi;  Cheung, Ka-Man;  Yang, Guanjun;  Leung, Chung-Hang
View  |  Adobe PDF(1178Kb)  |  Favorite  |  View/Download:366/15  |  Submit date:2018/10/30
G-quadruplex  Enzyme  Iridium(Iii) Complex  Luminescent Enhancement