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Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
Authors:  Yang, Guan-Jun;  Wang, Wanhe;  Mok, Simon Wing Fai;  Wu, Chun;  Law, Betty Yuen Kwan;  Miao, Xiang-Min;  Wu, Ke-Jia;  Zhong, Hai-Jing;  Wong, Chun-Yuen;  Wong, Vincent Kam Wai;  Ma, Dik-Lung;  Leung, Chung-Hang
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Drug Discovery  Epigenetics  Medicinal Chemistry  Triple-negative Breast Cancer  
MLKL mediates apoptosis via a mutual regulation with PERK/eIF2 alpha pathway in response to reactive oxygen species generation Journal article
APOPTOSIS, 2018,Volume: 23,Issue: 9-10,Page: 521-531
Authors:  Wen‑Xiang Cao;  Ting Li;  Zheng‑Hai Tang;  Le‑Le Zhang;  Zhao‑Yu Wang;  Xia Guo;  Min‑Xia Su;  Xiuping Chen;  Jin‑Jian Lu
Favorite  |  View/Download:6/0  |  Submit date:2020/01/09
Mlkl  Eif2α  Ros  Apoptosis  Chelerythrine  
Identification of a rhodium(III) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 20,Page: 2463-2466
Authors:  Yang, Guan-Jun;  Zhong, Hai-Jing;  Ko, Chung-Nga;  Wong, Suk-Yu;  Vellaisamy, Kasipandi;  Ye, Min;  Ma, Dik-Lung;  Leung, Chung-Hang
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Small Molecule Pin1 Inhibitor Blocking NF-B Signaling in Prostate Cancer Cells Journal article
CHEMISTRY-AN ASIAN JOURNAL, 2018,Volume: 13,Issue: 3,Page: 275-279
Authors:  Wu, Ke-Jia;  Zhong, Hai-Jing;  Yang, Guanjun;  Wu, Chun;  Huang, Jie-Min;  Li, Guodong;  Ma, Dik-Lung;  Leung, Chung-Hang
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Enzymes  Natural Products  Pin1  Protein-protein Interactions  Virtual Screening  
Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing Journal article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018,Volume: 143,Page: 1021-1027
Authors:  Wu, Ke-Jia;  Zhong, Hai-Jing;  Li, Guodong;  Liu, Chenfu;  Wang, Hui-Min David;  Ma, Dik-Lung;  Leung, Chung-Hang
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Drug Repurposing  Mitoxantrone  Nedd8  Ubiquitin  
A natural product-like JAK2/STAT3 inhibitor induces apoptosis of malignant melanoma cells Journal article
PLOS ONE, 2017,Volume: 12,Issue: 6
Authors:  Wu, Ke-Jia;  Huang, Jie-Min;  Zhong, Hai-Jing;  Dong, Zhen-Zhen;  Vellaisamy, Kasipandi;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Chiu, Pauline;  Kwong, Daniel W. J.;  Han, Quan-Bin;  Ma, Dik-Lung;  Leung, Chung-Hang
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Osimertinib induces autophagy and apoptosis via reactive oxygen species generation in non-small cell lung cancer cells Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 321,Page: 18-26
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
Osimertinib  Azd9291  Autophagy  Apoptosis  Ros  
BAG5 Interacts with DJ-1 and Inhibits the Neuroprotective Effects of DJ-1 to Combat Mitochondrial Oxidative Damage Journal article
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2017
Authors:  Qin, Li-Xia;  Tan, Jie-qiong;  Zhang, Hai-nan;  Rizwana, Kousar;  Lu, Jia-hong;  Tang, Jian-guang;  Jiang, Bo;  Shen, Xiang-min;  Guo, Ji-feng;  Tang, Bei-sha;  Tan, Li-ming;  Wang, Chun-yu
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An efficient level set method based on multi-scale image segmentation and hermite differential operator Journal article
Neurocomputing, 2016,Volume: 188,Page: 90-101
Authors:  Xiao-Feng Wang;  Hai Min;  Le Zou;  Yi-Gang Zhang;  Yuan-Yan Tang;  Chun-Lung Philip Chen
Favorite  |  View/Download:9/0  |  Submit date:2019/02/11
Hermite Differential Operator  Image Segmentation  Intensity Inhomogeneity  Level Set  Multi-scale  
Breaking ground in cross-cultural research on the fear of being laughed at (gelotophobia): A multi-national study involving 73 countries Journal article
Humor, 2009,Volume: 22,Issue: 2018-01-02,Page: 253
Authors:  Proyer R.T.;  Ruch W.;  Ali N.S.;  Al-Olimat H.S.;  Amemiya T.;  Adal T.A.;  Ansari S.A.;  Arhar P.;  Asem G.;  Baudin N.;  Bawab S.;  Bergen D.;  Brdar I.;  Brites R.;  Brunner-Sciarra M.;  Carrell A.;  Dios H.C.;  Celik M.;  Ceschi G.;  Chang K.;  Guo-Hai C.;  Cheryomukhin A.;  Chik M.P.Y.;  Chlopicki W.;  Cranney J.;  Dahourou D.;  Doosje S.;  Dore M.;  El-Arousy N.;  Fickova E.;  Führ M.;  Gallivan J.;  Geling H.;  Germikova L.;  Giedraityte M.;  Goh A.;  González R.D.;  Ho S.K.;  Hrebícková M.;  Jaime B.;  Kaare B.H.;  Kamble S.;  Kazarian S.;  Kerkkänen P.;  Klementová M.;  Kobozeva I.M.;  Kovjanic S.;  Kumaraswamy N.;  Lampert M.;  Liao C.-C.;  Levesque M.;  Loizou E.;  Díaz Loving R.;  Lyttle J.;  MacHline V.C.;  McGoldrick S.;  McRorie M.;  Min L.;  Mõttus R.;  Munyae M.M.;  Navia C.E.;  Nkhalamba M.;  Pedrini P.P.;  Petkova M.;  Platt T.;  Popa D.-E.;  Radomska A.;  Rashid T.;  Rawlings D.;  Rubio V.J.;  Samson A.C.;  Sarid O.;  Shams S.;  Sisokohm S.;  Smári J.;  Sneddon I.;  Snikhovska I.;  Stephanenko E.A.;  Stokenberga I.;  Stuer H.;  Tanoto Y.S.R.;  Tapia L.;  Taylor J.;  Thibault P.;  Thompson A.;  Thörn H.;  Toyota H.;  Ujlaky J.;  Vanno V.;  Wang J.;  Van Der Westhuizen B.;  Wijayathilake D.;  Wong P.S.O.;  Wycoff E.B.;  Yeun E.J.
Favorite  |  View/Download:4/0  |  Submit date:2018/10/30
Cross-cultural comparisons  Gelotophobia  Humor  Laughter  Multi-national study