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Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2 Journal article
Bioorganic and Medicinal Chemistry, 2009,Volume: 17,Issue: 2,Page: 731-740
Authors:  Duncton M.A.J.;  Piatnitski Chekler E.L.;  Katoch-Rouse R.;  Sherman D.;  Wong W.C.;  Smith II L.M.;  Kawakami J.K.;  Kiselyov A.S.;  Milligan D.L.;  Balagtas C.;  Hadari Y.R.;  Wang Y.;  Patel S.N.;  Rolster R.L.;  Tonra J.R.;  Surguladze D.;  Mitelman S.;  Kussie P.;  Bohlen P.;  Doody J.F.
Favorite | View/Download:8/0 | TC[WOS]:31 TC[Scopus]:34 | Submit date:2019/01/16
Angiogenesis  Arylphthalazine  Inhibitor  KDR  Kinase  Phthalazine  VEGFR-2  
Synthesis and evaluation of heteroaryl-ketone derivatives as a novel class of VEGFR-2 inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2008,Volume: 18,Issue: 15,Page: 4344-4347
Authors:  Piatnitski Chekler E.L.;  Katoch-Rouse R.;  Kiselyov A.S.;  Sherman D.;  Ouyang X.;  Kim K.;  Wang Y.;  Hadari Y.R.;  Doody J.F.
Favorite | View/Download:7/0 | TC[WOS]:9 TC[Scopus]:10 | Submit date:2019/01/16
Angiogenesis  Kinase inhibitor  Vascular endothelial growth factor  
Inhibitory activity of cetuximab on epidermal growth factor receptor mutations in non-small cell lung cancers Journal article
Molecular Cancer Therapeutics, 2007,Volume: 6,Issue: 10,Page: 2642-2651
Authors:  Doody J.F.;  Wang Y.;  Patel S.N.;  Joynes C.;  Sui P.L.;  Gerlak J.;  Rolser R.L.;  Li Y.;  Steiner P.;  Bassi R.;  Hicklin D.J.;  Hadari Y.R.
Favorite | View/Download:20/0 | TC[WOS]:42 TC[Scopus]:48 | Submit date:2019/01/16
Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 19,Page: 5102-5106
Authors:  Smith II L.;  Wong W.C.;  Kiselyov A.S.;  Burdzovic-Wizemann S.;  Mao Y.;  Xu Y.;  Duncton M.A.J.;  Kim K.;  Piatnitski E.L.;  Doody J.F.;  Wang Y.;  Rosler R.L.;  Milligan D.;  Columbus J.;  Balagtas C.;  Lee S.P.;  Konovalov A.;  Hadari Y.R.
Favorite | View/Download:6/0 | TC[WOS]:29 TC[Scopus]:32 | Submit date:2019/01/16
Diazepine  Epidermal growth factor receptor  Kinase inhibitor  Oxazepine  Thiazepine  
Tricyclic azepine derivatives: Pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 6,Page: 1643-1646
Authors:  Smith II L.;  Piatnitski E.L.;  Kiselyov A.S.;  Ouyang X.;  Chen X.;  Burdzovic-Wizemann S.;  Xu Y.;  Wang Y.;  Rosler R.L.;  Patel S.N.;  Chiang H.-H.;  Milligan D.L.;  Columbus J.;  Wong W.C.;  Doody J.F.;  Hadari Y.R.
Favorite | View/Download:9/0 | TC[WOS]:18 TC[Scopus]:17 | Submit date:2019/01/16
Benzoxazepine  Epidermal growth factor receptor  Kinase inhibitor  Kinase selectivity