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Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite | View/Download:35/0 | TC[WOS]:3 TC[Scopus]:4 | Submit date:2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation  
Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol Journal article
International Journal of Oncology, 2016,Volume: 49,Issue: 4,Page: 1576-1588
Authors:  Xu S.-W.;  Law B.Y.K.;  Mok S.W.F.;  Leung E.L.H.;  Fan X.X.;  Coghi P.S.;  Zeng W.;  Leung C.-H.;  Ma D.-L.;  Liu L.;  Wong V.K.W.
Favorite | View/Download:14/0 | TC[WOS]:12 TC[Scopus]:16 | Submit date:2018/11/06
Autophagy  Calcium  Celastrol  Epidermal Growth Factor Receptor  Gefitinib-resistant Lung Cancer  
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines Journal article
European Journal of Pharmacology, 2016,Volume: 789,Page: 458-467
Authors:  Yang Z.;  Tam K.Y.
Favorite | View/Download:10/0 | TC[WOS]:16 TC[Scopus]:16 | Submit date:2018/12/18
Dichloroacetate  Drug Combination  Epidermal Growth Factor Receptor  Erlotinib  Gefitinib  Pyruvate Dehydrogenase Kinase  
Prognostic significance of combining VEGFA, FLT1 and KDR mRNA expression in lung cancer Journal article
Oncology Letters, 2015,Volume: 10,Issue: 3,Page: 1893-1901
Authors:  Zhang S.-D.;  McCrudden C.M.;  Kwok H.F.
Favorite | View/Download:8/0 | TC[WOS]:11 TC[Scopus]:14 | Submit date:2018/12/19
Angiogenesis  Fms‑related Tyrosine Kinase 1  Kinase Insert Domain Receptor  Lung Cancer  Survival  Vascular Epidermal Growth Factor a  
Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 19,Page: 5102-5106
Authors:  Smith II L.;  Wong W.C.;  Kiselyov A.S.;  Burdzovic-Wizemann S.;  Mao Y.;  Xu Y.;  Duncton M.A.J.;  Kim K.;  Piatnitski E.L.;  Doody J.F.;  Wang Y.;  Rosler R.L.;  Milligan D.;  Columbus J.;  Balagtas C.;  Lee S.P.;  Konovalov A.;  Hadari Y.R.
Favorite | View/Download:5/0 | TC[WOS]:29 TC[Scopus]:32 | Submit date:2019/01/16
Diazepine  Epidermal growth factor receptor  Kinase inhibitor  Oxazepine  Thiazepine  
Tricyclic azepine derivatives: Pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 6,Page: 1643-1646
Authors:  Smith II L.;  Piatnitski E.L.;  Kiselyov A.S.;  Ouyang X.;  Chen X.;  Burdzovic-Wizemann S.;  Xu Y.;  Wang Y.;  Rosler R.L.;  Patel S.N.;  Chiang H.-H.;  Milligan D.L.;  Columbus J.;  Wong W.C.;  Doody J.F.;  Hadari Y.R.
Favorite | View/Download:9/0 | TC[WOS]:18 TC[Scopus]:17 | Submit date:2019/01/16
Benzoxazepine  Epidermal growth factor receptor  Kinase inhibitor  Kinase selectivity