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Recombinant-fully-human-antibody decorated highly-stable far-red AIEdots for in vivo HER-2 receptor-targeted imaging Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 53,Page: 7314-7317
Authors:  Wu, Yayun;  Chen, Zhizhen;  Zhang, Pengfei;  Zhou, Lihua;  Jiang, Tao;  Chen, Huajie;  Gong, Ping;  Dimitrov, Dimiter S.;  Cai, Lintao;  Zhao, Qi
Favorite | View/Download：66/0 | TC[WOS]:11 TC[Scopus]:11 | Submit date：2018/10/30
N-terminal alpha-amino group modification of antibodies using a site-selective click chemistry method Journal article
MABS, 2018,Volume: 10,Issue: 5,Page: 712-719
Authors:  De-zhi Li;  Bing-nan Han;  Rui Wei;  Gui-yang Yao;  Zhizhen Chen;  Jie Liu;  Terence C.W. Poon;  Wu Su;  Zhongyu Zhu;  Dimiter S. Dimitrov;  Qi Zhao
Favorite | View/Download：89/0 | TC[WOS]:13 TC[Scopus]:13 | Submit date：2020/06/30
Antibody  Antibody Engineering  Antibody-drug Conjugate  Click Chemistry  Site-specific Modification  
A dual-specific IGF-I/II human engineered antibody domain inhibits IGF signaling in breast cancer cells Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 7,Page: 799–806
Authors:  Zhizhen Chen;  Jie Liu;  Dafeng Chu;  Yaming Shan;  Guixing Ma;  Hongmin Zhang;  Xiaohua Douglas Zhang;  Pu Wang;  Qiang Chen;  Chuxia Deng;  Weizao Chen;  Dimiter Dimitrov;  Qi Zhao
Favorite | View/Download：18/0 | TC[WOS]:4 TC[Scopus]:4 | Submit date：2018/12/17
Insulin-like Growth Factor  Yeast Display  Affinity Maturation  Ead  
Engineered antibody CH2 domains binding to nucleolin: Isolation, characterization and improvement of aggregation Journal article
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017,Volume: 485,Issue: 2,Page: 446-453
Authors:  Li, Dezhi;  Gong, Rui;  Zheng, Jun;  Chen, Xihai;  Dimitrov, Dimiter S.;  Zhao, Qi
Favorite | View/Download：31/0 | TC[WOS]:12 TC[Scopus]:11 | Submit date：2018/10/30
Antibody Domain  Ch2  Nucleolin  Yeast Display  Monoclonal Antibody  Aggregation Prone Region  
A dual specific anti-IGF-1/IGF-2 human monoclonal antibody alone and in combination with temsirolimus for therapy of neuroblastoma Journal article
INTERNATIONAL JOURNAL OF CANCER, 2015,Volume: 137,Issue: 9,Page: 2243-2252
Authors:  Qi Zhao;  Hoa Tran;  Dimiter S. Dimitrov;  Nai-Kong V. Cheung
Favorite | View/Download：5/0 | TC[WOS]:13 TC[Scopus]:13 | Submit date：2019/01/23
Igf-1  Igf-2  Temsirolimus  Chemotherapy  Neuroblastoma  
Human monoclonal antibodies targeting nonoverlapping epitopes on insulin-like growth factor II as a novel type of candidate cancer therapeutics Journal article
MOLECULAR CANCER THERAPEUTICS, 2012,Volume: 11,Issue: 7,Page: 1400-1410
Authors:  Weizao Chen;  Yang Feng;  Qi Zhao;  Zhongyu Zhu;  Dimiter S. Dimitrov
Favorite | View/Download：6/0 | TC[WOS]:19 TC[Scopus]:20 | Submit date：2019/01/23
Human monoclonal antibodies to IGF1/2 with picomolar affinity Journal article
MOLECULAR CANCER THERAPEUTICS, 2011,Volume: 10,Issue: 9,Page: 1677-1685
Authors:  Qi Zhao;  Yang Feng;  Zhongyu Zhu;  Dimiter S. Dimitrov
Favorite | View/Download：7/0 | TC[WOS]:30 TC[Scopus]:31 | Submit date：2019/01/23
Mab  Igf2  Picomolar Affinity  Phage Display  Yeast Display  Igf1  
Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies Journal article
JOURNAL OF VIROLOGY, 2011,Volume: 85,Issue: 21,Page: 11401-11408
Authors:  Zhongyu Zhu;  Haiyan Rebekah Qin;  Weizao Chen;  Qi Zhao;  Xiaoying Shen;  Robert Schutte;  Yanping Wang;  Gilad Ofek;  Emily Streaker;  Ponraj Prabakaran;  Genevieve G. Fouda;  Hua-Xin Liao;  John Owens;  Mark Louder;  Yongping Yang;  Kristina-Ana Klaric;  M. Anthony Moody;  John R. Mascola;  Jamie K. Scott;  Peter D. Kwong;  David Montefiori;  Barton F. Haynes;  Georgia D. Tomaras;  Dimiter S. Dimitrov
Favorite | View/Download：8/0 | TC[WOS]:67 TC[Scopus]:69 | Submit date：2019/01/23
Shortened Engineered Human Antibody CH2 Domains: Increased Stability and Binding to the Human Neonatal Receptor Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2011,Volume: 286,Issue: 31,Page: 27288-27293
Authors:  Rui Gong;  Yanping Wang;  Yang Feng;  Qi Zhao;  Dimiter S. Dimitrov
Favorite | View/Download：7/0 | TC[WOS]:39 TC[Scopus]:43 | Submit date：2019/01/23
Engineered single human CD4 domains as potent HIV-1 inhibitors and components of vaccine immunogens Journal article
JOURNAL OF VIROLOGY, 2011,Volume: 85,Issue: 18,Page: 9395–9405
Authors:  Weizao Chen;  Yang Feng;  Rui Gong;  Zhongyu Zhu;  Yanping Wang;  Qi Zhao;  Dimiter S. Dimitrov
Favorite | View/Download：4/0 | TC[WOS]:25 TC[Scopus]:25 | Submit date：2019/01/23