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Non-classical estrogen signaling in ovarian cancer improves chemo-sensitivity and patients outcome Journal article
THERANOSTICS, 2019,Volume: 9,Issue: 13,Page: 3952-3965
Authors:  Dapeng Hao;  Jingjing Li;  Jianlin Wang;  Yuan Meng;  Zhiqiang Zhao;  Chao Zhang;  Kai Miao;  Chuxia Deng;  Benjamin K. Tsang;  Li Wang;  Li-jun Di
Favorite  |  View/Download:9/0  |  Submit date:2020/05/21
Ovarian Cancer  Estrogen Signaling  Deficiency Of Homologous-recombination  Chemotherapy  Hormone Replacement  
PP2AC alpha deficiency impairs early cortical development through inducing DNA damage in neuroprojenitor cells Journal article
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2019,Volume: 109,Page: 40-58
Authors:  Bo Liu;  Lin Lin;  Saima Riazuddin;  Ahmed Zubair;  Li Wang;  Li-Jun Di;  Rui Li;  Ting-Ting Dong;  Chu-Xia Deng;  Wei-Min Tong
Favorite  |  View/Download:6/0  |  Submit date:2020/05/26
Protein Phosphorylation  Brain Development  Dna Damage  Stem Cell  Signaling Cascade  
Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice Journal article
Journal of Cellular Physiology, 2019,Volume: 234,Issue: 1,Page: 595-605
Authors:  Wang Q.;  Tan Q.;  Xu W.;  Kuang L.;  Zhang B.;  Wang Z.;  Ni Z.;  Su N.;  Jin M.;  Li C.;  Jiang W.;  Huang J.;  Li F.;  Zhu Y.;  Chen H.;  Du X.;  Chen D.;  Deng C.;  Qi H.;  Xie Y.;  Chen L.
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Activing Receptor-like Kinases 5 (Alk5)  Matrix Degradation  Meniscal Degeneration  Transforming Growth Factor-β (Tgf-β) Signaling  
Current Progresses of Exosomes as Cancer Diagnostic and Prognostic Biomarkers Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2019,Volume: 15,Issue: 1,Page: 1-11
Authors:  Huang, Tao;  Deng, Chu-Xia
Favorite  |  View/Download:11/0  |  Submit date:2019/01/17
exosomes  cancer  biomarkers  therapy  diagnosis  prognosis  
The epigenetically downregulated factor CYGB suppresses breast cancer through inhibition of glucose metabolism Journal article
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2018,Volume: 37
Authors:  Feng, Yixiao;  Wu, Mingjun;  Li, Shuman;  He, Xiaoqian;  Tang, Jun;  Peng, Weiyan;  Zeng, Beilei;  Deng, Chuxia;  Ren, Guosheng;  Xiang, Tingxiu
Favorite  |  View/Download:8/0  |  Submit date:2019/01/17
CYGB  GLUT1  HXK2  p53  Breast cancer  Metabolism  Glycolysis  
Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model Journal article
Molecular Therapy - Nucleic Acids, 2018,Volume: 13,Page: 291-302
Authors:  Luo F.;  Xie Y.;  Wang Z.;  Huang J.;  Tan Q.;  Sun X.;  Li F.;  Li C.;  Liu M.;  Zhang D.;  Xu M.;  Su N.;  Ni Z.;  Jiang W.;  Chang J.;  Chen H.;  Chen S.;  Xu X.;  Deng C.;  Wang Z.;  Du X.;  Chen L.
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Adeno-associated Virus  Apert Syndrome  Craniosynostosis  Fgfr2  Molecular Therapy  Rnai  
A novel FGFR1-binding peptide attenuates the degeneration ofarticular cartilage in adult mice Journal article
Osteoarthritis and Cartilage, 2018,Volume: 26,Issue: 12,Page: 1733-1743
Authors:  Q. Tan;  B. Chen;  Q. Wang;  W.Xu;  Y.Wang;  Z. Lin;  F.Luo;  S. Huang;  Y.Zhu;  N. Su;  M. Jin;  C.Li;  L. Kuang;  H.Qi;  Z.Ni;  Z. Wang;  X. Luo;  W. Jiang;  H. Chen;  S. Chen;  F.Li;  B. Zhang;  J. Huang;  R. Zhang;  K. Jin;  X.Xu;  C. Deng;  X.Du;  Y. Xie;  L. Chen
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Fgfr1  Peptide  Osteoarthritis  Mice  
A novel FGFR1-binding peptide attenuates the degeneration of articular cartilage in adult mice Journal article
Osteoarthritis and Cartilage, 2018,Volume: 26,Issue: 12,Page: 1733-1743
Authors:  Tan Q.;  Chen B.;  Wang Q.;  Xu W.;  Wang Y.;  Lin Z.;  Luo F.;  Huang S.;  Zhu Y.;  Su N.;  Jin M.;  Li C.;  Kuang L.;  Qi H.;  Ni Z.;  Wang Z.;  Luo X.;  Jiang W.;  Chen H.;  Chen S.;  Li F.;  Zhang B.;  Huang J.;  Zhang R.;  Jin K.;  Xu X.;  Deng C.;  Du X.;  Xie Y.;  Chen L.
Favorite  |  View/Download:10/0  |  Submit date:2018/12/17
FGFR1  Mice  Osteoarthritis  Peptide  
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-Gly374Arg mutation in achondroplasia in mice Journal article
The Journal of Biological Chemistry, 2018
Authors:  Kai Miao;  Xin Zhang;  Sek Man Su;  Jianming Zeng;  Zebin Huang;  Un In Chan;  Xiaoling Xu;  Chu-Xia Deng
Favorite  |  View/Download:23/0  |  Submit date:2018/12/17
Fgfr3  Crispr/cas9  Protein  Targeted Correction  Off-target  Achondroplasia  Dwarfism  Genome Editing  Gene Therapy  
BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy Journal article
Human molecular genetics, 2018
Authors:  Xiaoling Xu;  Eric Chen;  Lihua Mo;  Lei Zhang;  Fangyuan Shao;  Kai Miao;  Jianlin Liu;  Sek Man Su;  Monica Valecha;  Un In Chan;  Hongping Zheng;  Mark Chen;  Weiping Chen;  Qiang Chen;  Haiqing Fu;  Mirit I. Aladjem;  Yanzhen He;  Chu-Xia Deng
Favorite  |  View/Download:35/0  |  Submit date:2018/12/17