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Insight into the Dissolution Molecular Mechanism of Ternary Solid Dispersions by Combined Experiments and Molecular Simulations Journal article
AAPS PHARMSCITECH, 2019,Volume: 20,Issue: 7
Authors:  Run Han;  Tianhe Huang;  Xinyang Liu;  Xinyang Liu;  Haifeng Li;  Jiahong Lu;  Yuanhui Ji;  Huimin Sun;  Defang Ouyang
Favorite  |  View/Download:4/0  |  Submit date:2020/03/25
Solid Dispersion  Dissolution Effect  Molecular Modeling  Ternary System  
Flaxseed extract induces apoptosis in human breast cancer MCF-7 cells Journal article
Food and Chemical Toxicology, 2019,Volume: 127,Page: 188-196
Authors:  Tingyan Hu;  Kegang Linghu;  Siqi Huang;  Maurizio Battino;  Milen I. Georgiev;  Gokhan Zengin;  Defang Li;  Yun Deng;  Y.T. Wang;  Hui Cao
Favorite  |  View/Download:7/0  |  Submit date:2020/03/27
Flaxseed  Mcf-7 cells  Apoptosis  Ros  Mitochondrial Membrane Potential  Dietary Supplement  
Investigating molecular interactions of high-loaded glipizide-HPMCAS microparticles by integrated experimental and modeling techniques Journal article
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019,Volume: 131,Page: 127-135
Authors:  Qiang Li;  Qianqian Zhao;  Qiufang Jing;  Xiaosi Ma;  Ning Chen;  Guobin Ren;  Defang Ouyang;  Fuzheng Ren
Favorite  |  View/Download:4/0  |  Submit date:2020/03/25
Glipizide  Hydroxypropyl Methylcellulose Acetate  Succinate (Hpmcas)  Molecular Interaction  Molecular Dynamics Simulation  
Analysis of the Literature and Patents on Solid Dispersions from 1980 to 2015 Journal article
MOLECULES, 2018,Volume: 23,Issue: 7
Authors:  Zhang, Jinglu;  Han, Run;  Chen, Weijie;  Zhang, Weixiang;  Li, Ying;  Ji, Yuanhui;  Chen, Lijiang;  Pan, Hao;  Yang, Xinggang;  Pan, Weisan;  Ouyang, Defang
Favorite  |  View/Download:15/0  |  Submit date:2018/10/30
Solid Dispersion  Big Data  Literature  Patent  Scientific Knowledge Mapping  Citespace  
Predicting oral disintegrating tablet formulations by neural network techniques Journal article
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018,Volume: 13,Issue: 4,Page: 336-342
Authors:  Han, Run;  Yang, Yilong;  Li, Xiaoshan;  Ouyang, Defang
Favorite  |  View/Download:21/0  |  Submit date:2018/10/30
Oral Disintegrating Tablets  Formulation Prediction  Artificial Neural Network  Deep Neural Network  Deep-learning  
Computer-Aided Formulation Design for a Highly Soluble Lutein-Cyclodextrin Multiple-Component Delivery System Journal article
MOLECULAR PHARMACEUTICS, 2018,Volume: 15,Issue: 4,Page: 1664-1673
Authors:  Zhao, Qianqian;  Miriyala, Nikhila;  Su, Yan;  Chen, Weijie;  Gao, Xuejiao;  Shao, Ling;  Yan, Ru;  Li, Haifeng;  Yao, Xiaojun;  Cao, Dongsheng;  Wang, Yitao;  Ouyang, Defang
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Lutein  Cyclodextrin  Multiple-component System  Molecular Dynamics Simulation  Bioavailability  Computer-aided Formulation Design  
MicroShare: Privacy-Preserved Medical Resource Sharing through MicroService Architecture Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018,Volume: 14,Issue: 8,Page: 907-919
Authors:  Yang, Yilong;  Zu, Quan;  Liu, Peng;  Ouyang, Defang;  Li, Xiaoshan
Favorite  |  View/Download:16/0  |  Submit date:2018/10/30
Ehr  Microservice  Privacy-preserved  Ehr Sharing  
Design and Evaluation of Hydrophilic Matrix System Containing Polyethylene Oxides for the Zero-Order Controlled Delivery of Water-Insoluble Drugs Journal article
AAPS PHARMSCITECH, 2017,Volume: 18,Issue: 1,Page: 82-92
Authors:  Wang, Lijie;  Chen, Kai;  Wen, Haoyang;  Ouyang, Defang;  Li, Xue;  Gao, Yunyun;  Pan, Weisan;  Yang, Xinggang
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Hydrophilic Matrix System  Polyethylene Oxides  Water Insoluble Drug  In Vitro Release  Viscosity  
Preparation and characterization of pelletized solid dispersion of resveratrol with mesoporous silica microparticles to improve dissolution by fluid-bed coating techniques Journal article
Asian Journal of Pharmaceutical Sciences, 2016,Volume: 11,Issue: 4,Page: 528-535
Authors:  Jian Li;  Xiaoqing Miao;  Tongkai Chen;  Defang Ouyang;  Ying Zheng
Favorite  |  View/Download:7/0  |  Submit date:2018/12/28
Amorphous  Fluid Bed  Mesoporous Silica Microparticles (Msm)  Resveratrol (Res)  Solid Dispersion  
Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers Journal article
Drug discovery today, 2013,Volume: 18,Issue: 5-6,Page: 290-297
Authors:  Li Gan;  Jing Wang;  Min Jiang;  Hanah Bartlett;  Defang Ouyang;  Frank Eperjesi;  Jianping Liu;  Yong Gan
Favorite  |  View/Download:1/0  |  Submit date:2019/01/23