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Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3β and the ERK Pathway Journal article
Cellular and Molecular Neurobiology, 2017,Volume: 37,Issue: 4,Page: 655-664
作者:  Yu J.;  Zheng J.;  Lin J.;  Jin L.;  Yu R.;  Mak S.;  Hu S.;  Sun H.;  Wu X.;  Zhang Z.;  Lee M.;  Tsim W.;  Su W.;  Zhou W.;  Cui W.;  Han Y.;  Wang Q.
收藏  |  浏览/下载:4/0  |  提交时间:2018/11/06
ERK  GSK3β  H2O2  Indirubin-3-oxime  PI3-K  
Inhibiting β-Amyloid-Associated Alzheimer’s Pathogenesis In Vitro and In Vivo by a Multifunctional Dimeric Bis(12)-hupyridone Derived from Its Natural Analogue Journal article
Journal of Molecular Neuroscience, 2015,Volume: 55,Issue: 4,Page: 1014
作者:  Hu S.;  Wang R.;  Cui W.;  Zhang Z.;  Mak S.;  Xu D.;  Choi C.;  Tsim K.W.;  Carlier P.R.;  Lee M.;  Han Y.
收藏  |  浏览/下载:0/0  |  提交时间:2018/10/30
Alzheimer’s disease  Aβ fibrils  Bis(12)-hupyridone  Cell viability  Memory impairment  Thioflavin T  
Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of GSK3β Journal article
Journal of Molecular Neuroscience, 2015,Volume: 57,Issue: 4,Page: 561
作者:  Hu S.;  Cui W.;  Zhang Z.;  Mak S.;  Xu D.;  Li G.;  Hu Y.;  Wang Y.;  Lee M.;  Tsim K.W.;  Han Y.
收藏  |  浏览/下载:2/0  |  提交时间:2018/10/30
6OHDA  GSK3β  Indirubin-3-oxime  MEF2D  Neuroprotection  Parkinson’s disease  
The co-delivery of a low-dose P-glycoprotein inhibitor with doxorubicin sterically stabilized liposomes against breast cancer with low P-glycoprotein expression Journal article
International Journal of Nanomedicine, 2014,Volume: 9,Issue: 1,Page: 3425-3437
作者:  Gao W.;  Lin Z.;  Chen M.;  Yang X.;  Cui Z.;  Zhang X.;  Yuan L.;  Zhang Q.
收藏  |  浏览/下载:4/0  |  提交时间:2018/12/27
Antitumor activity  Cyclosporine A  Liposomes  Low-P-gp-expressing tumor  Targeted delivery  
The novel tetramethylpyrazine bis-nitrone (TN-2) protects against MPTP/MPP+-induced neurotoxicity via inhibition of mitochondrial-dependent apoptosis Journal article
Journal of Neuroimmune Pharmacology, 2014,Volume: 9,Issue: 2,Page: 245-258
作者:  Xu D.;  Duan H.;  Zhang Z.;  Cui W.;  Wang L.;  Sun Y.;  Lang M.;  Hoi P.M.;  Han Y.;  Wang Y.;  Lee S.M.
收藏  |  浏览/下载:6/0  |  提交时间:2018/11/06
Dopaminergic Neuron  Mitochondrial-dependent Apoptosis  Mptp  Parkinson's Disease  
A novel Danshensu derivative confers cardioprotection via PI3K/Akt and Nrf2 pathways Journal article
International Journal of Cardiology, 2013,Volume: 168,Issue: 2,Page: 1349
作者:  Cui G.;  Shan L.;  Hung M.;  Lei S.;  Choi I.;  Zhang Z.;  Yu P.;  Hoi P.;  Wang Y.;  Lee S.M.Y.
收藏  |  浏览/下载:7/0  |  提交时间:2018/10/30
Cardioprotection  Danshensu Derivative  Ischemia  Nrf2  Oxidative Stress