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Zebrafish: A Promising Model for Evaluating the Toxicity of Carbon Dot-Based Nanomaterials Journal article
ACS Applied Materials and Interfaces, 2020,Volume: 12,Issue: 43,Page: 49012-49020
Authors:  Liu,Wei;  Huang,Gang;  Su,Xiaoying;  Li,Siyi;  Wang,Qun;  Zhao,Yuying;  Liu,Yao;  Luo,Jingshan;  Li,Ye;  Li,Chuwen;  Yuan,Dongsheng;  Hong,Honghai;  Chen,Xiaojia;  Chen,Tongkai
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carbon nanomaterials  developmental neurotoxicity  dopamine  nanotoxicology  zebrafish (Danio rerio)  
Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome Journal article
Aging and Disease, 2020,Volume: 11,Issue: 3,Page: 559-574
Authors:  Zhou,Hefeng;  Li,Shengnan;  Li,Chuwen;  Yang,Xuanjun;  Li,Haitao;  Zhong,Hanbing;  Lu,Jia Hong;  Lee,Simon Ming Yuen
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Degradation  Neuroprotection  Parkinson's disease  Proteasome  α-synuclein  
Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models Journal article
Neurotherapeutics, 2019,Volume: 16,Issue: 4,Page: 1225-1236
Authors:  Zhou,Hefeng;  Shao,Min;  Guo,Baojian;  Li,Chuwen;  Lu,Yucong;  Yang,Xuanjun;  ShengnanLi,;  Li,Haitao;  Zhu,Qi;  Zhong,Hanbing;  Wang,Yuqiang;  Zhang,Zaijun;  Lu,Jiahong;  Lee,Simon Ming Yuen
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Degradation  LMP7  Parkinson’s disease  Proteasome activity  α-synuclein  
Neuroprotective Effects of BHDPC, a Novel Neuroprotectant, on Experimental Stroke by Modulating Microglia Polarization Journal article
ACS CHEMICAL NEUROSCIENCE, 2019,Volume: 10,Issue: 5,Page: 2434-2449
Authors:  Chuwen Li;  Yaqi Bian;  Yu Feng;  Fan Tang;  Liang Wang;  Maggie Pui Man Hoi;  Dan Ma;  Chao Zhao;  Simon Ming Yuen Lee
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Bhdpc  Ischemic Stroke  Microglia  Nf-κb  Creb  Pka  
Suppressive effects of the supercritical-carbon dioxide fluid extract of Chrysanthemum indicum on chronic unpredictable mild stress-induced depressive-like behavior in mice Journal article
FOOD & FUNCTION, 2019,Volume: 10,Issue: 2,Page: 1212-1224
Authors:  Xiaoli Wu;  Benqin Tang;  Xian Liao;  Ziren Su;  Simon Ming-Yuen Lee;  Yefeng Cai;  Chuwen Li
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Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo Journal article
Oxidative Medicine and Cellular Longevity, 2019,Volume: 2019
Authors:  Zhou,Hefeng;  Shao,Min;  Yang,Xuanjun;  Li,Chuwen;  Cui,Guozhen;  Gao,Cheng;  Di,Lijun;  Zhong,Hanbing;  Wang,Yuqiang;  Zhang,Zaijun;  Lee,Simon Ming Yuen
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Pinostrobin Exerts Neuroprotective Actions in Neurotoxin-Induced Parkinson's Disease Models through Nrf2 Induction Journal article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018,Volume: 66,Issue: 31,Page: 8307-8318
Authors:  Li, Chuwen;  Tang, Benqin;  Feng, Yu;  Tang, Fan;  Hoi, Maggie Pui-Man;  Su, Ziren;  Lee, Simon Ming-Yuen
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Pinostrobin  Parkinson's Disease  Neurotoxin  Nrf2  
Schisantherin a attenuates neuroinflammation in activated microglia: Role of Nrf2 activation through ERK phosphorylation Journal article
Cellular Physiology and Biochemistry, 2018,Volume: 47,Issue: 5,Page: 1769-1784
Authors:  Li,Chuwen;  Chen,Tongkai;  Zhou,Hefeng;  Zhang,Chao;  Feng,Yu;  Tang,Fan;  Hoi,Maggie Pui Man;  He,Chengwei;  Zheng,Ying;  Lee,Simon Ming Yuen
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Microglia  Neuroinflammation  NF-κB  Nrf2  Schisantherin A  
BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-kappa B and Activating PKA/CREB Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Li, Chuwen;  Chen, Tongkai;  Zhou, Hefeng;  Feng, Yu;  Hoi, Maggie P. M.;  Ma, Dan;  Zhao, Chao;  Zheng, Ying;  Lee, Simon M. Y.
Favorite | View/Download:47/0 | TC[WOS]:6 TC[Scopus]:6 | Submit date:2018/10/30
Bhdpc  Neuroinflammation  Microglia  Nf-kappa b  Creb  Pka  
Inhibitory Effects of Betulinic Acid on LPS-Induced Neuroinflammation Involve M2 Microglial Polarization via CaMKK beta-Dependent AMPK Activation Journal article
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018,Volume: 11
Authors:  Li, Chuwen;  Zhang, Chao;  Zhou, Hefeng;  Feng, Yu;  Tang, Fan;  Hoi, Maggie P. M.;  He, Chengwei;  Ma, Dan;  Zhao, Chao;  Lee, Simon M. Y.
Favorite | View/Download:45/0 | TC[WOS]:26 TC[Scopus]:27 | Submit date:2018/10/30
Amp-activated Protein Kinase  Betulinic Acid  Calmodulin-dependent Protein Kinase Beta  Microglia Polarization  Neuroinflammation