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Hydroxyurea Facilitates Manifestation of Disease Relevant Phenotypes in Patients-Derived IPSCs-Based Modeling of Late-Onset Parkinson’s Disease Journal article
AGING AND DISEASE, 2019,Volume: 10,Issue: 5,Page: 1037-1048
Authors:  Yuan Tan;  Minjing Ke;  Zhijian Huang;  Cheong-Meng Chong;  Xiaotong Cen;  Jia-Hong Lu;  Xiaoli Yao;  Dajiang Qin;  Huanxing Su
Favorite  |  View/Download:9/0  |  Submit date:2020/04/08
Disease Phenotypes  Er Stress  Induced Pluripotentstem Cells  Parkinson’s Disease  Hydroxyurea  
Using induced pluripotent stem cells for modeling Parkinson’s disease Journal article
WORLD JOURNAL OF STEM CELLS, 2019,Volume: 11,Issue: 9,Page: 634-649
Authors:  Minjing Ke;  Cheong-Meng Chong;  Huanxing Su
Favorite  |  View/Download:8/0  |  Submit date:2020/04/08
Parkinson’s Disease  Dopaminergic Neurons  Induced Pluripotent Stem Cells  Somatic Cell Reprogramming  Aging  
The effects of bioactive components from the rhizome of Salvia miltiorrhiza (Danshen) on the characteristics of Alzheimer's disease Journal article
Chinese Medicine, 2019,Volume: 14
Authors:  Cheong‑Meng Chong;  Huanxing Su;  Jin‑Jian Lu;  Yitao Wang
Favorite  |  View/Download:4/0  |  Submit date:2020/03/27
Alzheimer’s Disease  Danshen  Amyloid β Plaques  Neurofbrillary Tangles  Mitochondrial Dysfunction  Autophagy  
The effects of bioactive components from the rhizome of Salvia miltiorrhiza(Danshen) on the characteristics of Alzheimer’s disease Journal article
CHINESE MEDICINE, 2019
Authors:  Cheong‑Meng Chong;  Huanxing Su;  Jin‑Jian Lu;  Yitao Wang
Favorite  |  View/Download:6/0  |  Submit date:2020/04/08
Alzheimer’s Disease  Amyloid β Plaques  Neurofibrillary Tangles  Mitochondrial Dysfunction  Autophagy  Danshen  
Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling Journal article
CELL DEATH & DISEASE, 2018,Volume: 9,Page: 1-13
Authors:  Cheong-Meng Chong;  Minjing Ke;  Yuan Tan;  Zhijian Huang;  Ke Zhang;  Nana Ai;  Wei Ge;  Dajiang Qin;  Jia-Hong Lu;  Huanxing Su
Favorite  |  View/Download:33/0  |  Submit date:2018/10/30
Ponatinib exerts anti-angiogenic effects in the zebrafish and human umbilical vein endothelial cells via blocking VEGFR signaling pathway Journal article
Oncotarget, 2018,Volume: 9,Issue: 62,Page: 31958-31970
Authors:  Nana Ai;  Cheong-Meng Chong.;  Weiting Chen;  Zhe Hu;  Huanxing Su;  Guokai Chen;  Queenie Wing Lei Wong;  Wei Ge
Favorite  |  View/Download:12/0  |  Submit date:2018/12/11
Angiogenesis  Enos  Huvec  Mapk  Ponatinib  
Berberine Protects Human Retinal Pigment Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Damage through Activation of AMPK Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018,Volume: 19,Issue: 6
Authors:  Li, Shuai;  Gaur, Uma;  Chong, Cheong-Meng;  Lin, Shaofen;  Fang, Jiankang;  Zeng, Zhiwen;  Wang, Haitao;  Zheng, Wenhua
Favorite  |  View/Download:22/0  |  Submit date:2018/10/30
Berberine  Age-related Macular Degeneration  D407 Cells  Ampk  
Roles of Nitric Oxide Synthase Isoforms in Neurogenesis Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 55,Issue: 3,Page: 2645-2652
Authors:  Chong, Cheong-Meng;  Ai, Nana;  Ke, Minjing;  Tan, Yuan;  Huang, Zhijian;  Li, Yong;  Lu, Jia-Hong;  Ge, Wei;  Su, Huanxing
Favorite  |  View/Download:27/0  |  Submit date:2018/10/30
Nitric Oxide  Nitric Oxide Synthase  Neural Stem Cells  Proliferation  Neurogenesis  
Discovery of a ROCK inhibitor, FPND, which prevents cerebral hemorrhage through maintaining vascular integrity by interference with VE-cadherin Journal article
CELL DEATH DISCOVERY, 2017,Volume: 3
Authors:  Shang Li;  Nana Ai;  Mingyun Shen;  Yuanye Dang;  Cheong-Meng Chong;  Peichen Pan;  Yiu Wa Kwan;  Shun Wan Chan;  George Pak Heng Leung;  Maggie Pui Man Hoi;  Tingjun Hou;  Simon Ming-Yuen Lee
Favorite  |  View/Download:235/0  |  Submit date:2020/01/16
ROCK in CNS: Different Roles of Isoforms and Therapeutic Target for Neurodegenerative Disorders Journal article
CURRENT DRUG TARGETS, 2017,Volume: 18,Issue: 4,Page: 455-462
Authors:  Chong, Cheong-Meng;  Ai, Nana;  Lee, Simon Ming-Yuen
Favorite  |  View/Download:20/0  |  Submit date:2018/10/30
Axonal Regeneration  Central Nervous System  Fasudil  Isoforms  Limk  Neurodegenerative Diseases  Rock