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MLKL mediates apoptosis via a mutual regulation with PERK/eIF2 alpha pathway in response to reactive oxygen species generation Journal article
APOPTOSIS, 2018,Volume: 23,Issue: 9-10,Page: 521-531
Authors:  Cao, Wen-Xiang;  Li, Ting;  Tang, Zheng-Hai;  Zhang, Le-Le;  Wang, Zhao-Yu;  Guo, Xia;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
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MLKL  eIF2 alpha  ROS  Apoptosis  Chelerythrine  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
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EMT  ERK1  2  lung cancer  Snail  toosendanin  
Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-kappa B, mitochondrial ROS, and MAPK pathways Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 355,Page: 1-8
Authors:  Wu, Xiaxia;  Gao, Hongwei;  Hou, Ying;  Yu, Jie;  Sun, Wen;  Wang, Ying;  Chen, Xiaoyan;  Feng, Yulin;  Xu, Qiong-ming;  Chen, Xiuping
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Dihydronortanshinone  Inflammation  LPS  Macrophage  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
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Nagilactone E  Non-small cell lung cancer  Cyclin B1  Cell cycle  Apoptosis  
Diethyl Blechnic, a Novel Natural Product Isolated from Salvia miltiorrhiza Bunge, Inhibits Doxorubicin-Induced Apoptosis by Inhibiting ROS and Activating JNK1/2 Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018,Volume: 19,Issue: 6
Authors:  Yu, Jie;  Gao, Hongwei;  Wu, Chuanhong;  Xu, Qiong-Ming;  Lu, Jin-Jian;  Chen, Xiuping
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diethyl blechnic  DOX  cardiotoxicity  ROS  JNK1  2  
1,3,6,7-Tetrahydroxy-8-prenylxanthone ameliorates inflammatory responses resulting from the paracrine interaction of adipocytes and macrophages Journal article
BRITISH JOURNAL OF PHARMACOLOGY, 2018,Volume: 175,Issue: 10,Page: 1590-1606
Authors:  Li, Dan;  Liu, Qianyu;  Sun, Wen;  Chen, Xiuping;  Wang, Ying;  Sun, Yuxiang;  Lin, Ligen
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Supramolecular Encapsulation and Bioactivity Modulation of a Halonium Ion by Cucurbit[n]uril (n=7, 8) Journal article
JOURNAL OF ORGANIC CHEMISTRY, 2018,Volume: 83,Issue: 8,Page: 4882-4887
Authors:  Yin, Hang;  Huang, Qiaoxian;  Zhao, Wenwen;  Bardelang, David;  Siri, Didier;  Chen, Xiuping;  Lee, Simon M. Y.;  Wang, Ruibing
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Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 344,Page: 35-45
Authors:  Guo, Yanling;  Wu, Xiaxia;  Wu, Qin;  Lu, Yuanfu;  Shi, Jingshan;  Chen, Xiuping
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15,16-Dihydrotanshinone I  Ulcerative colitis  Inflammation  Necroptosis  
Recent progress in doxorubicin-induced cardiotoxicity and protective potential of natural products Journal article
PHYTOMEDICINE, 2018,Volume: 40,Page: 125-139
Authors:  Yu, Jie;  Wang, Changxi;  Kong, Qi;  Wu, Xiaxia;  Lu, Jin-Jian;  Chen, Xiuping
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Doxorubicin  Cardiotoxicity  Natural products  
Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells Journal article
SCIENTIFIC REPORTS, 2018,Volume: 8
Authors:  Wu, Chuanhong;  Zhao, Wenwen;  Yu, Jie;  Li, Shaojing;  Lin, Ligen;  Chen, Xiuping
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