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BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-kappa B and Activating PKA/CREB Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Li, Chuwen;  Chen, Tongkai;  Zhou, Hefeng;  Feng, Yu;  Hoi, Maggie P. M.;  Ma, Dan;  Zhao, Chao;  Zheng, Ying;  Lee, Simon M. Y.
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BHDPC  neuroinflammation  microglia  NF-kappa B  CREB  PKA  
Schisantherin A Attenuates Neuroinflammation in Activated Microglia: Role of Nrf2 Activation Through ERK Phosphorylation Journal article
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018,Volume: 47,Issue: 5,Page: 1769-1784
Authors:  Li, Chuwen;  Chen, Tongkai;  Zhou, Hefeng;  Zhang, Chao;  Feng, Yu;  Tang, Fan;  Hoi, Maggie Pui-Man;  He, Chengwei;  Zheng, Ying;  Lee, Simon Ming-Yuen
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Schisantherin a  Neuroinflammation  Microglia  Nrf2  Nf-kappa b  
Zebrafish: A promising in vivo model for assessing the delivery of natural products, fluorescence dyes and drugs across the blood-brain barrier Journal article
PHARMACOLOGICAL RESEARCH, 2017,Volume: 125,Page: 246-257
Authors:  Li, Ye;  Chen, Tongkai;  Miao, Xiaoqing;  Yi, Xiang;  Wang, Xueqing;  Zhao, Haitao;  Lee, Simon Ming-Yuen;  Zheng, Ying
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Blood Brain Barrier (Bbb)  Zebrafish  Fluorescence Dyes  Natural Products  Drug Delivery Systems  Permeability  
Pluronic P85/F68 Micelles of Baicalein Could Interfere with Mitochondria to Overcome MRP2-Mediated Efflux and Offer Improved Anti-Parkinsonian Activity Journal article
MOLECULAR PHARMACEUTICS, 2017,Volume: 14,Issue: 10,Page: 3331-3342
Authors:  Chen, Tongkai;  Li, Ye;  Li, Chuwen;  Yi, Xiang;  Wang, Ruibing;  Lee, Simon Ming-Yuen;  Zheng, Ying
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micelles  baicalein  fluorescence resonance energy transfer (FRET)  multidrug resistance-associated protein 2 (MRP2)  mitochondria  neuroprotective effect  
Tablets of multi-unit pellet system for controlled drug delivery Journal article
JOURNAL OF CONTROLLED RELEASE, 2017,Volume: 262,Page: 222-231
Authors:  Chen, Tongkai;  Li, Jian;  Chen, Ting;  Zheng, Ying;  Sun, Changquan Calvin
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Multi-unit Pellet System (Mups)  Pellets  Coating  Cushioning Agents  Tableting Of Pellets  Drug Delivery System (Dds)  
Small-Sized mPEG PLGA Nanoparticles of Schisantherin A with Sustained Release for Enhanced Brain Uptake and Anti-Parkinsonian Activity Journal article
ACS APPLIED MATERIALS & INTERFACES, 2017,Volume: 9,Issue: 11,Page: 9516-9527
Authors:  Chen, Tongkai;  Li, Chuwen;  Li, Ye;  Yi, Xiang;  Wang, Ruibing;  Lee, Simon Ming-Yuen;  Zheng, Ying
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
Brain Delivery  Cellular Uptake  Fluorescence Resonance Energy Transfer (Fret)  Mpeg-plga Nanoparticles  Oral Bioavailability  Schisantherin a