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Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite  |  View/Download:6/0  |  Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
Chaetominine induces cell cycle arrest in human leukemia K562 and colon cancer SW1116 cells Journal article
ONCOLOGY LETTERS, 2018,Volume: 16,Issue: 4,Page: 4671-4678
Authors:  Yao, Jingyun;  Xiao, Jianbo;  Wei, Xing;  Lu, Yanhua
Favorite  |  View/Download:25/0  |  Submit date:2018/10/30
Cell Cycle Arrest  Cyclin  Cyclin-dependent Kinase  Chaetominine  K562 Cells  Sw1116 Cells  
Reversal of paclitaxel resistance in human ovarian cancer cells with redox-responsive micelles consisting of alpha-tocopheryl succinate-based polyphosphoester copolymers Journal article
ACTA PHARMACOLOGICA SINICA, 2017,Volume: 38,Issue: 6,Page: 859-873
Authors:  Chen, Feng-qian;  Zhang, Jin-ming;  Fang, Xie-fan;  Yu, Hua;  Liu, Yu-ling;  Li, Hui;  Wang, Yi-tao;  Chen, Mei-wan
Favorite  |  View/Download:14/0  |  Submit date:2018/10/30
Ovarian Carcinoma  Paclitaxel  Multidrug Resistance  Nanomedicines  D-alpha-tocopheryl Succinate  Redox-responsive Micelles  P-gp  Apoptosis  Cell Cycle Arrest  A2780/ptx Cells  
Reversal of paclitaxel resistance in human ovarian cancer cells with redox-responsive micelles consisting of α-Tocopheryl succinate-based polyphosphoester copolymers Journal article
Acta Pharmacologica Sinica, 2017,Volume: 38,Issue: 6,Page: 859
Authors:  Chen F.-Q.;  Zhang J.-M.;  Fang X.-F.;  Yu H.;  Liu Y.-L.;  Li H.;  Wang Y.-T.;  Chen M.-W.
Favorite  |  View/Download:16/0  |  Submit date:2018/10/31
A2780/ptx Cells  Apoptosis  Cell Cycle Arrest  d-?-tocopheryl Succinate  Multidrug Resistance  Nanomedicines  Ovarian Carcinoma  P-gp  Paclitaxel  Redox-responsive Micelles  
Shikonin derivative DMAKO-05 inhibits akt signal activation and melanoma proliferation Journal article
Chemical Biology and Drug Design, 2016,Volume: 87,Issue: 6,Page: 895-904
Authors:  Yang Y.-Y.;  He H.-Q.;  Cui J.-H.;  Nie Y.-J.;  Wu Y.-X.;  Wang R.;  Wang G.;  Zheng J.-N.;  Ye R.D.;  Wu Q.;  Li S.-S.;  Qian F.
Favorite  |  View/Download:6/0  |  Submit date:2018/11/07
apoptosis  cell cycle arrest  cytotoxicity  DMAKO-05  melanoma cell B16F0  shikonin  
Effects of alisol B 23-acetate on ovarian cancer cells: G1 phase cell cycle arrest, apoptosis, migration and invasion inhibition Journal article
Phytomedicine, 2016,Volume: 23,Issue: 8,Page: 800
Authors:  Zhang L.-L.;  Xu Y.-L.;  Tang Z.-H.;  Xu X.-H.;  Chen X.;  Li T.;  Ding C.-Y.;  Huang M.-Q.;  Chen X.-P.;  Wang Y.-T.;  Yuan X.-F.;  Lu J.-J.
Favorite  |  View/Download:7/0  |  Submit date:2018/10/31
Alisol b 23-acetate  Apoptosis  Cell Cycle Arrest  Invasion  Migration  Ovarian Cancer  
Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis Journal article
Inflammopharmacology, 2014,Volume: 22,Issue: 2,Page: 127-134
Authors:  Li W.-Y.;  Ng Y.-F.;  Zhang H.;  Guo Z.-D.;  Guo D.-J.;  Kwan Y.-W.;  Leung G.P.-H.;  Lee S.M.-Y.;  Yu P.H.-F.;  Chan S.-W.
Favorite  |  View/Download:12/0  |  Submit date:2018/11/06
Cell cycle arrest  DNA fragmentation  Emodin  Growth inhibition  
Alkaloids Isolated from Natural Herbs as the Anticancer Agents Journal article
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2012,Issue: 4,Page: 623-644
Authors:  Lu, JJ (Lu, Jin-Jian);  Bao, JL (Bao, Jiao-Lin);  Chen, XP (Chen, Xiu-Ping);  HHuang, M (Huang, Min);  Wang, YT (Wang, Yi-Tao)
View  |  Adobe PDF(2331Kb)  |  Favorite  |  View/Download:330/64  |  Submit date:2018/11/01
Cell-cycle Arrest  Sanguinarine-induced Apoptosis  Suppresses Tumor-growth  Swiss Albino Mice  Matrine Inhibits Proliferation  Hepatocellular-carcinoma Cells  Mediated Multidrug-resistance  Buccal Pouch Carcinogenesis  Berberine-induced Apoptosis  Induced Lung Carcinogenesis  
Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae - A review Journal article
JOURNAL OF ETHNOPHARMACOLOGY, 2012,Volume: 143,Issue: 2,Page: 406-411
Authors:  Lu, JJ (Lu, Jin-Jian);  Dang, YY (Dang, Yuan-Ye);  Huang, M (Huang, Min);  Xu, WS (Xu, Wen-Shan);  Chen, XP (Chen, Xiu-Ping);  Wang, YT (Wang, Yi-Tao)
View  |  Adobe PDF(345Kb)  |  Favorite  |  View/Download:372/54  |  Submit date:2018/11/01
Cell-cycle Arrest  Chromatography-mass-spectrometry  Human Lung-carcinoma  Breast-cancer Cells  Beta-elemene  Delta-elemene  In-vitro  D-galactosamine/lipopolysaccharide  Inhibitory-activity  Glioblastoma Cells  
Biological activities and potential molecular targets of cucurbitacins: a focus on cancer Journal article
ANTI-CANCER DRUGS, 2012,Volume: 23,Issue: 8,Page: 777-787
Authors:  Chen, XP (Chen, Xiuping);  Bao, JL (Bao, Jiaolin);  Guo, JJ (Guo, Jiajie);  Ding, Q (Ding, Qian);  Lu, JJ (Lu, Jinjian);  Huang, MQ (Huang, Mingqing);  Wang, YT (Wang, Yitao)
Favorite  |  View/Download:6/0  |  Submit date:2018/11/01
Cell-cycle Arrest  Cell-cycle Arrest  Bryonia-alba l  Pancreatic-cancer  Inhibitory-activity  Antitumor-activity  Signaling Pathway  Leukemia-cells  Melanoma-cells  In-vitro