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Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology Journal article
FRONTIERS IN PHARMACOLOGY, 2019
Authors:  Ning-Ning Yuan;  Cui-Zan Cai;  Ming-Yue Wu;  Qi Zhu;  HuanXing Su;  Min Li;  JiaoYan Ren;  Jie-Qiong Tan;  Jia-Hong Lu
Favorite  |  View/Download:24/0  |  Submit date:2020/04/14
Canthin-6-one  Parkinson’s Disease  Alpha-synuclein  Ubiquitin-proteasome-system  Crispr/cas9  Rpn2/psmd1  Pka  
Selective autophagy: The new player in the fight against neurodegenerative diseases? Journal article
BRAIN RESEARCH BULLETIN, 2018,Volume: 137,Page: 79-90
Authors:  Wu, Ming-Yue;  Song, Ju-Xian;  Wang, Sheng-Fang;  Cai, Cui-Zan;  Li, Min;  Lu, Jia-Hong
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Selective Autophagy  Neurodegenerative Diesease  Aggrephagy  Chaperone-mediated Autophagy  Mitophagy  
Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 44,Page: 77673-77684
Authors:  Wu, Ming-Yue;  Wang, Sheng-Fang;  Cai, Cui-Zan;  Tan, Jie-Qiong;  Li, Min;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Wang, Yi-Tao;  Zheng, Wei;  Lu, Jia-Hong
Favorite  |  View/Download:27/0  |  Submit date:2018/10/30
Dauricine  Daurisoline  Autophagy Blocker  Cancer Cells  Cell Toxicity  
Baicalein prevents 6-OHDA/ascorbic acid-induced calcium-dependent dopaminergic neuronal cell death Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Wang, Sheng-Fang;  Liu, Liang-Feng;  Wu, Ming-Yue;  Cai, Cui-Zan;  Su, Huanxing;  Tan, Jieqiong;  Lu, Jia-Hong;  Li, Min
Favorite  |  View/Download:33/0  |  Submit date:2018/10/30
NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models Journal article
AUTOPHAGY, 2017,Volume: 13,Issue: 12,Page: 2028-2040
Authors:  Yang, Chuanbin;  Cai, Cui-Zan;  Song, Ju-Xian;  Tan, Jie-Qiong;  Durairajan, Siva Sundara Kumar;  Iyaswamy, Ashok;  Wu, Ming-Yue;  Chen, Lei-Lei;  Yue, Zhenyu;  Li, Min;  Lu, Jia-Hong
Favorite  |  View/Download:28/0  |  Submit date:2018/10/30
a Beta  Alzheimer's Disease  App  Autophagy  Class Iii Phosphatidylinositol 3-kinase (Ptdins3k)  Nrbf2