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PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A Journal article
CANCER LETTERS, 2018,Volume: 436,Page: 28-37
作者:  Liu, Yifan;  Yang, Eun Ju;  Zhang, Baoyuan;  Miao, Zhengqiang;  Wu, Changjie;  Lyu, Junfang;  Tan, Kaeling;  Poon, Terence Chuen Wai;  Shim, Joong Sup
收藏  |  浏览/下载:14/0  |  提交时间:2018/10/30
Akt  Kw2449  Synthetic Lethality  Aurka  Drug Combination  
Osimertinib resistance in non-small cell lung cancer: Mechanisms and therapeutic strategies Journal article
CANCER LETTERS, 2018,Volume: 420,Page: 242-246
作者:  Tang, Zheng-Hai;  Lu, Jin-Jian
收藏  |  浏览/下载:12/0  |  提交时间:2018/10/30
Osimertinib  Azd9291  Egfr Tki  Resistant Mechanisms  Therapeutic Strategies  
Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer Journal article
CANCER LETTERS, 2018,Volume: 412,Page: 1-9
作者:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Guo, Xia;  Dai, Xiao-Yang;  Lu, Jia-Hong;  Chen, Xiuping;  Zhu, Hong;  Lu, Jin-Jian
收藏  |  浏览/下载:13/0  |  提交时间:2018/10/30
Cepharanthine  Autophagy  Lysosome  Dacomitinib  Nsclc  
Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth Journal article
CANCER LETTERS, 2017,Volume: 409,Page: 91-103
作者:  Lyu, Junfang;  Yang, Eun Ju;  Head, Sarah A.;  Ai, Nana;  Zhang, Baoyuan;  Wu, Changjie;  Li, Ruo-Jing;  Liu, Yifan;  Yang, Chen;  Dang, Yongjun;  Kwon, Ho Jeong;  Ge, Wei;  Liu, Jun O.;  Shim, Joong Sup
收藏  |  浏览/下载:15/0  |  提交时间:2018/10/30
Cholesterol Trafficking  Angiogenesis  Tumor  Lysosome  Cepharanthine  
An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-kappa B Journal article
CANCER LETTERS, 2017,Volume: 396,Page: 76-84
作者:  Kang, Tian-Shu;  Wang, Wanhe;  Zhong, Hai-Jing;  Dong, Zhen-Zhen;  Huang, Qi;  Mok, Simon Wing Fai;  Leung, Chung-Hang;  Wong, Vincent Kam Wai;  Ma, Dik-Lung
收藏  |  浏览/下载:10/0  |  提交时间:2018/10/30
Benzofuran-conjugated iridium(III) complex  STAT3  NF-kappa B  Prostate cells  Dual inhibitors  
Hemodynamic shear stress stimulates migration and extravasation of tumor cells by elevating cellular oxidative level Journal article
CANCER LETTERS, 2017,Volume: 388,Page: 239-248
作者:  Ma, Shijun;  Fu, Afu;  Chiew, Geraldine Giap Ying;  Luo, Kathy Qian
收藏  |  浏览/下载:17/0  |  提交时间:2018/10/30
Circulating Tumor Cells  Shear Stress  Reactive Oxygen Species  Erk1/2  Cell Migration  Extravasation  
An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-κB Journal article
Cancer Letters, 2017,Volume: 396,Page: 76
作者:  Kang T.-S.;  Wang W.;  Zhong H.-J.;  Dong Z.-Z.;  Huang Q.;  Mok S.W.F.;  Leung C.-H.;  Wong V.K.W.;  Ma D.-L.
收藏  |  浏览/下载:8/0  |  提交时间:2018/10/30
Benzofuran-conjugated Iridium(Iii) Complex  Dual Inhibitors  Nf-κb  Prostate Cells  Stat3  
NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth Journal article
Cancer Letters, 2015,Volume: 359,Issue: 1,Page: 97-106
作者:  Zha X.;  Hu Z.;  Ji S.;  Jin F.;  Jiang K.;  Li C.;  Zhao P.;  Tu Z.;  Chen X.;  Di L.;  Zhou H.;  Zhang H.
收藏  |  浏览/下载:1/0  |  提交时间:2018/12/21
Aerobic glycolysis  Glut3  MTOR  NFκB  Tumorigenesis  
Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonism Journal article
Cancer Letters, 2015,Volume: 362,Issue: 1,Page: 106-115
作者:  Shim J.S.;  Li R.-J.;  Lv J.;  Head S.A.;  Yang E.J.;  Liu J.O.
收藏  |  浏览/下载:2/0  |  提交时间:2019/01/15
Angiogenesis  Cholesterol Trafficking  Selective Estrogen Receptor Modulator  Tamoxifen  
Dual functions of gold nanorods as photothermal agent and autofluorescence enhancer to track cell death during plasmonic photothermal therapy Journal article
Cancer Letters, 2015,Volume: 357,Issue: 1,Page: 152-159
作者:  Kannadorai R.K.;  Chiew G.G.Y.;  Luo K.Q.;  Liu Q.
收藏  |  浏览/下载:1/0  |  提交时间:2018/12/18
Autofluorescence  Gold Nanorods  Hyperthermia  Necrosis  Photothermal Therapy  Renal Cell Carcinoma