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Development of a Liposomal Formulation of Acetyltanshinone IIA for Breast Cancer Therapy Journal article
MOLECULAR PHARMACEUTICS, 2019,Volume: 16,Issue: 9,Page: 3873-3886
Authors:  Qi Wang;  Man Luo;  Na We;  Alex Chang;  Kathy Qian Luo
Favorite  |  View/Download:36/0  |  Submit date:2020/05/12
Anti-breast Cancer Drugs  Acetyltanshinone Iia (Ata)  Mpeg-liposomes  Bioavailabilit  Pharmacokinetics  Toxicity Study  
A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Xinhua Zhou;  Anqi Wang;  Liang Wang;  Jianhua Yin;  Li Wang;  Lijun Di;  Maggie Pui-Man Hoi;  Luchen Shan;  Xu Wu;  Yuqiang Wang
Favorite  |  View/Download:9/0  |  Submit date:2020/05/21
Danshensu  Tetramethylpyrazine  Breast Cancer  Resistance  Glycolysis  P-glycoprotein  
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019,Volume: 71,Issue: 3,Page: 306-315
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen;  Edwin Cheung;  Kin Yip Tam
Favorite  |  View/Download:10/0  |  Submit date:2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite  |  View/Download:6/0  |  Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
The epigenetically downregulated factor CYGB suppresses breast cancer through inhibition of glucose metabolism Journal article
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2018,Volume: 37
Authors:  Feng, Yixiao;  Wu, Mingjun;  Li, Shuman;  He, Xiaoqian;  Tang, Jun;  Peng, Weiyan;  Zeng, Beilei;  Deng, Chuxia;  Ren, Guosheng;  Xiang, Tingxiu
Favorite  |  View/Download:8/0  |  Submit date:2019/01/17
CYGB  GLUT1  HXK2  p53  Breast cancer  Metabolism  Glycolysis  
The expression of ubiquitin-specific peptidase 8 and its prognostic role in patients with breast cancer Journal article
Journal of Cellular Biochemistry, 2018,Volume: 119,Issue: 12,Page: 10051-10058
Authors:  Qiu H.;  Kong J.;  Cheng Y.;  Li G.
Favorite  |  View/Download:11/0  |  Submit date:2019/01/15
breast cancer  clinical prognosis  ubiquitin-specific peptidase 8  
Pharmacological Inhibition of LSD1 for Cancer Treatment Journal article
MOLECULES, 2018,Volume: 23,Issue: 12
Authors:  Yang, Guan-Jun;  Lei, Pui-Man;  Wong, Suk-Yu;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite  |  View/Download:15/0  |  Submit date:2019/01/17
Lsd1  Demethylase  Histone  Breast Cancer  Prostate Cancer  Acute Myeloid Leukemia  Cancer Therapy  
Single-Cell Transcriptome Analysis Reveals Estrogen Signaling Coordinately Augments One-Carbon, Polyamine, and Purine Synthesis in Breast Cancer Journal article
Cell Reports, 2018,Volume: 25,Issue: 8,Page: 2285-2298.e4
Authors:  Zhu D.;  Zhao Z.;  Cui G.;  Chang S.;  Hu L.;  See Y.X.;  Lim M.G.L.;  Guo D.;  Chen X.;  Robson P.;  Luo Y.;  Cheung E.
Favorite  |  View/Download:13/0  |  Submit date:2018/12/17
Breast Cancer  Estrogen Receptor α  Metabolic Switch  Single-cell Rna Sequencing  
Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
Authors:  Yang, Guan-Jun;  Wang, Wanhe;  Mok, Simon Wing Fai;  Wu, Chun;  Law, Betty Yuen Kwan;  Miao, Xiang-Min;  Wu, Ke-Jia;  Zhong, Hai-Jing;  Wong, Chun-Yuen;  Wong, Vincent Kam Wai;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite  |  View/Download:36/0  |  Submit date:2018/10/30
Drug Discovery  Epigenetics  Medicinal Chemistry  Triple-negative Breast Cancer  
DNA replication licensing protein MCM10 promotes tumor progression and is a novel prognostic biomarker and potential therapeutic target in breast cancer Journal article
Cancers, 2018,Volume: 10,Issue: 9
Authors:  Mahadevappa R.;  Neves H.;  Yuen S.M.;  Jameel M.;  Bai Y.;  Yuen H.-F.;  Zhang S.-D.;  Zhu Y.;  Lin Y.;  Kwok H.F.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/19
Breast Cancer  Knockdown  Mcm10  Overexpression  Proliferation  Survival