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Brain-targeted delivery shuttled by black phosphorus nanostructure to treat Parkinson's disease Journal article
Biomaterials, 2020,Volume: 260
Authors:  Xiong,Sha;  Li,Zhongjun;  Liu,Yao;  Wang,Qun;  Luo,Jingshan;  Chen,Xiaojia;  Xie,Zhongjian;  Zhang,Yuan;  Zhang,Han;  Chen,Tongkai
Favorite | View/Download:0/0 | TC[WOS]:0 TC[Scopus]:2 | Submit date:2021/03/02
Black phosphorus nanosheets  Blood-brain barrier  Brain targeting  Drug delivery  Lactoferrin  
NIR-II-Activated Yolk-Shell Nanostructures as an Intelligent Platform for Parkinsonian Therapy Journal article
ACS Applied Bio Materials, 2020,Volume: 3,Issue: 10,Page: 6876-6887
Authors:  Liu,Yao;  Zhu,Daoming;  Luo,Jingshan;  Chen,Xiaojia;  Gao,Liqian;  Liu,Wei;  Chen,Tongkai
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blood-brain barrier  brain drug delivery  gold nanorods  mesoporous silica  neurodegenerative disorders  NIR-II biowindow  
Highly stabilized nanocrystals delivering Ginkgolide B in protecting against the Parkinson's disease Journal article
International Journal of Pharmaceutics, 2020,Volume: 577
Authors:  Liu,Yao;  Liu,Wei;  Xiong,Sha;  Luo,Jingshan;  Li,Ye;  Zhao,Yuying;  Wang,Qun;  Zhang,Zexin;  Chen,Xiaojia;  Chen,Tongkai
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Blood-brain barrier  Drug delivery  Gastrointestinal tract  Nanocrystals  Parkinson's disease  
Polymeric nanoparticles-based brain delivery with improved therapeutic efficacy of ginkgolide b in parkinson’s disease Journal article
International Journal of Nanomedicine, 2020,Volume: 15,Page: 10453-10467
Authors:  Zhao,Yuying;  Xiong,Sha;  Liu,Piaoxue;  Liu,Wei;  Wang,Qun;  Liu,Yao;  Tan,Hanxu;  Chen,Xiaojia;  Shi,Xuguang;  Wang,Qi;  Chen,Tongkai
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Blood–brain barrier  Drug delivery system  Endocytosis  PD treatment  Zebrafish  
Nanoparticles mediating the sustained puerarin release facilitate improved brain delivery to treat parkinson's disease Journal article
ACS Applied Materials and Interfaces, 2019,Volume: 11,Issue: 48,Page: 45276-45289
Authors:  Chen,Tongkai;  Liu,Wei;  Xiong,Sha;  Li,Dongli;  Fang,Shuhuan;  Wu,Zhenfeng;  Wang,Qi;  Chen,Xiaojia
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brain delivery  nanoparticles  neuroprotective effects  puerarin  sustained release  
Oral Delivery of Puerarin Nanocrystals To Improve Brain Accumulation and Anti-Parkinsonian Efficacy Journal article
MOLECULAR PHARMACEUTICS, 2019,Volume: 16,Issue: 4,Page: 1444-1455
Authors:  Sha Xiong;  Wei Liu;  Dongli Li;  Xiaojia Chen;  Fang Liu;  Dongsheng Yuan;  Huafeng Pan;  Qi Wang;  Shuhuan Fang;  Tongkai Chen
Favorite | View/Download:16/0 | TC[WOS]:11 TC[Scopus]:13 | Submit date:2020/01/06
Parkinson’s Disease  Brain Accumulation  Nanocrystals  Oral Delivery  Puerarin  
Zebrafish: A promising in vivo model for assessing the delivery of natural products, fluorescence dyes and drugs across the blood-brain barrier Journal article
PHARMACOLOGICAL RESEARCH, 2017,Volume: 125,Page: 246-257
Authors:  Li, Ye;  Chen, Tongkai;  Miao, Xiaoqing;  Yi, Xiang;  Wang, Xueqing;  Zhao, Haitao;  Lee, Simon Ming-Yuen;  Zheng, Ying
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Blood Brain Barrier (Bbb)  Zebrafish  Fluorescence Dyes  Natural Products  Drug Delivery Systems  Permeability  
Small-Sized mPEG PLGA Nanoparticles of Schisantherin A with Sustained Release for Enhanced Brain Uptake and Anti-Parkinsonian Activity Journal article
ACS APPLIED MATERIALS & INTERFACES, 2017,Volume: 9,Issue: 11,Page: 9516-9527
Authors:  Chen, Tongkai;  Li, Chuwen;  Li, Ye;  Yi, Xiang;  Wang, Ruibing;  Lee, Simon Ming-Yuen;  Zheng, Ying
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Brain Delivery  Cellular Uptake  Fluorescence Resonance Energy Transfer (Fret)  Mpeg-plga Nanoparticles  Oral Bioavailability  Schisantherin a  
Small-Sized mPEG-PLGA Nanoparticles of Schisantherin A with Sustained Release for Enhanced Brain Uptake and Anti-Parkinsonian Activity Journal article
ACS Applied Materials and Interfaces, 2017,Volume: 9,Issue: 11,Page: 9516-9527
Authors:  Chen T.;  Li C.;  Li Y.;  Yi X.;  Wang R.;  Lee S.M.-Y.;  Zheng Y.
Favorite | View/Download:6/0 | TC[WOS]:30 TC[Scopus]:34 | Submit date:2018/12/28
brain delivery  cellular uptake  fluorescence resonance energy transfer (FRET)  mPEG−PLGA nanoparticles  oral bioavailability  Schisantherin A  
Oral delivery of a nanocrystal formulation of schisantherin a with improved bioavailability and brain delivery for the treatment of Parkinson's disease Journal article
Molecular Pharmaceutics, 2016,Volume: 13,Issue: 11,Page: 3864-3875
Authors:  Tongkai Chen;  Chuwen Li;  Ye Li;  Xiang Yi;  Simon Ming-Yuen Lee;  Ying Zheng
Favorite | View/Download:13/0 | TC[WOS]:23 TC[Scopus]:25 | Submit date:2018/11/06
Brain Delivery  Dissolution  Nanocrystals  Oral Bioavailability  Parkinson's Disease (Pd)