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Structure-based repurposing of FDA-approved drugs as inhibitors of NEDD8-activating enzyme Journal article
Biochimie, 2014,Volume: 102,Issue: 1,Page: 211-215
Authors:  Zhong H.-J.;  Liu L.-J.;  Chan D.S.-H.;  Wang H.-M.;  Chan P.W.H.;  Ma D.-L.;  Leung C.-H.
Favorite  |  View/Download:0/0  |  Submit date:2018/11/06
Inhibitor  NEDD8-activating enzyme  Repurposing  Structure-based  Virtual screening  
Mycoepoxydiene induces apoptosis and inhibits TPA-induced invasion in human cholangiocarcinoma cells via blocking NF-κB pathway Journal article
Biochimie, 2014,Volume: 101,Issue: 1,Page: 183-191
Authors:  Li W.;  Li M.;  Su X.;  Qin L.;  Miao M.;  Yu C.;  Shen Y.;  Luo Q.;  Chen Q.
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Apoptosis  Cholangiocarcinoma  Invasion  Mycoepoxydiene  Nf-κb  
Inhibition of Cathepsin S by Fsn0503 enhances the efficacy of chemotherapy in colorectal carcinomas Journal article
Biochimie, 2012,Volume: 94,Issue: 2,Page: 487-493
Authors:  Burden R.E.;  Gormley J.A.;  Kuehn D.;  Ward C.;  Kwok H.F.;  Gazdoiu M.;  McClurg A.;  Jaquin T.J.;  Johnston J.A.;  Scott C.J.;  Olwill S.A.
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Angiogenesis  Cathepsin  Chemotherapy  Invasion  
Discovery of a natural product inhibitor targeting protein neddylation by structure-based virtual screening Journal article
Biochimie, 2012,Volume: 94,Issue: 11,Page: 2457
Authors:  Zhong H.-J.;  Pui-Yan Ma V.;  Cheng Z.;  Shiu-Hin Chan D.;  He H.-Z.;  Leung K.-H.;  Ma D.-L.;  Leung C.-H.
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Drug discovery  Natural product  NEDD8-activating enzyme  Ubiquitin-like protein  Virtual screening  
Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer Journal article
Biochimie, 2011,Volume: 93,Issue: 6,Page: 1055-1064
Authors:  Chan D.S.-H.;  Yang H.;  Kwan M.H.-T.;  Cheng Z.;  Lee P.;  Bai L.-P.;  Jiang Z.-H.;  Wong C.-Y.;  Fong W.-F.;  Leung C.-H.;  Ma D.-L.
Favorite  |  View/Download:3/0  |  Submit date:2018/11/06
c-myc G-quadruplex  FDA-approved drug  Methylene blue  Repurposing  Structure-based optimization  
Molecular property-binding affinity relationship of flavonoids for common rat plasma proteins in vitro Journal article
Biochimie, 2011,Volume: 93,Issue: 2,Page: 134-140
Authors:  Xiao J.;  Cao H.;  Chen T.;  Yang F.;  Liu C.;  Xu X.
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Affinity  Common rat plasma proteins  Flavonoids  Molecular property  
A Dictyostelium discoideum gene, which is highly related to mo15 from Xenopus, is expressed during growth but not during development. Journal article
Biochemistry and cell biology = Biochimie et biologie cellulaire, 1995,Volume: 73,Issue: 1-2,Page: 51-58
Authors:  Michaelis C.;  Luo Q.;  Weeks G.
Favorite  |  View/Download:1/0  |  Submit date:2018/12/18