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Identification of a Wells-Dawson polyoxometalate-based AP-2 gamma inhibitor with pro-apoptotic activity Journal article
BIOCHEMICAL JOURNAL, 2018,Volume: 475,Issue: 11,Page: 1965-1977
Authors:  Hu, Jiamiao;  Tan, Si Kee;  Lim, Michelle Gek Liang;  Chang, Shie Hong;  Cui, Guimei;  Liu, Shanshan;  Narasimhan, Kamesh;  New, Siu Yee;  Wang, Xuecong;  Chen, Congling;  Chakravarty, Harapriya;  Kolatkar, Prasanna R.;  Tam, Kin Yip;  Lu, Qian;  Su, Xiaodi;  Jauch, Ralf;  Cheung, Edwin
Favorite  |  View/Download:16/0  |  Submit date:2018/10/30
Ap-2γ  Breast Cancer  Fluorescent Anisotropic  Polyoxometalate  
Identification of a Wells-Dawson polyoxometalatebased AP-2γ inhibitor with pro-apoptotic activity Journal article
Biochemical Journal, 2018,Volume: 475,Issue: 11,Page: 1965-1977
Authors:  Hu J.;  Tan S.K.;  Lim M.G.L.;  Chang S.H.;  Cui G.;  Liu S.;  Narasimhan K.;  New S.Y.;  Wang X.;  Chen C.;  Chakravarty H.;  Kolatkar P.R.;  Tam K.Y.;  Lu Q.;  Su X.;  Jauch R.;  Cheung E.
Favorite  |  View/Download:5/0  |  Submit date:2018/12/17
Evaluation in zebrafish model of the toxicity of rhodamine B-conjugated crotamine, a peptide potentially useful for diagnostics and therapeutics Journal article
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2017,Volume: 31,Issue: 11
Authors:  Chan, Judy Yuet-Wa;  Zhou, Hefeng;  Kwan, Yiu Wa;  Chan, Shun Wan;  Radis-Baptista, Gandhi;  Lee, Simon Ming-Yuen
Favorite  |  View/Download:20/0  |  Submit date:2018/10/30
acute toxicity  rhodamine B-crotamine  screening of pharmaceuticals  venom-derived peptides  zebrafish model  
RNA-Seq Reveals Acute Manganese Exposure Increases Endoplasmic Reticulum Related and Lipocalin mRNAs in Caenorhabditis elegans Journal article
Journal of Biochemical and Molecular Toxicology, 2016,Volume: 30,Issue: 2,Page: 97-105
Authors:  Rudgalvyte M.;  Peltonen J.;  Lakso M.;  Nass R.;  Wong G.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/18
Heavy Metal  Model Organism  Next-generation Sequencing  Rnai  Transcriptomics  
V101L of human formyl peptide receptor 1 (FPR1) increases receptor affinity and augments the antagonism mediated by cyclosporins Journal article
Biochemical Journal, 2013,Volume: 451,Issue: 2,Page: 245-255
Authors:  Zhou C.;  Zhou Y.;  Wang J.;  Feng Y.;  Wang H.;  Xue J.;  Chen Y.;  Ye R.D.;  Wang M.-W.
Favorite  |  View/Download:2/0  |  Submit date:2018/11/07
Cyclosporin  Formyl peptide receptor 1 (FPR1)  Haplotype  Pharmacogenomics  Receptor affinity  Single nucleotide polymorphism  
Chronic ethanol exposure increases cytochrome P-450 and decreases activated in blocked unfolded protein response gene family transcripts in caenorhabditis elegans Journal article
Journal of Biochemical and Molecular Toxicology, 2013,Volume: 27,Issue: 3,Page: 219-228
Authors:  Peltonen J.;  Aarnio V.;  Heikkinen L.;  Lakso M.;  Wong G.
Favorite  |  View/Download:0/0  |  Submit date:2018/12/18
Caenorhabditis elegans  Endoplasmic Reticulum Stress  Ethanol, RNA-seq  Gene Expression  Model Organism  Next-Generation Sequencing  Oxidative Stress  
Rfa2 is specifically dephosphorylated by Pph3 in Candida albicans Journal article
Biochemical Journal, 2013,Volume: 449,Issue: 3,Page: 673-681
Authors:  Wang H.;  Gao J.;  Wong A.H.-H.;  Hu K.;  Li W.;  Wang Y.;  Sang J.
Favorite  |  View/Download:2/0  |  Submit date:2019/01/16
Dephosphorylation  DNA replication  Phosphatase  Protein-DNA interaction  Replication protein A (RPA)  
Recombinant expression, reconstitution and structure of human anaphase-promoting complex (APC/C) Journal article
Biochemical Journal, 2012,Volume: 449,Issue: 2,Page: 365-371
Authors:  Ziguo Zhang;  Jing Yang;  Eric H. Kong;  William C. H. Chao;  Edward P. Morris;  Paula C. A. da Fonseca
Favorite  |  View/Download:8/0  |  Submit date:2018/12/18
Anaphase-promoting Complex/cyclosome (Apc/c)  Cell Cycle  Recombinant Expression  Single-particle Electron Microscopy  Three-dimensional Structure  Ubiquitination  
Trans fat diet causes decreased brood size and shortened lifespan in Caenorhabditis elegans delta-6-desaturase mutant fat-3 Journal article
Journal of Biochemical and Molecular Toxicology, 2011,Volume: 25,Issue: 5,Page: 269-279
Authors:  Reisner K.;  Lehtonen M.;  Storvik M.;  Jantson T.;  Lakso M.;  Callaway J.C.;  Wong G.
Favorite  |  View/Download:1/0  |  Submit date:2018/12/18
Diet  Free Fatty Acids  Microarray  Model Organism  Transcriptomics  
DNA-binding activity of the transcription factor upstream stimulatory factor 1 (USF-1) is regulated by cyclin-dependent phosphorylation Journal article
Biochemical Journal, 1999,Volume: 344,Issue: 1,Page: 145-152
Authors:  Cheung E.;  Mayr P.;  Coda-Zabetta F.;  Woodman P.G.;  Boam D.S.W.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/17
cdk1  Cyclin  DNA-binding domain  USF  USR