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Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2019,Volume: 27,Issue: 17,Page: 3879-3888
Authors:  Bin Xu;  Mo-Yu Ding;  Zhibing Weng;  Zheng-Qing Li;  Feng Li;  Xia Sun;  Qiu-Ling Chen;  Yi-Tao Wang;  Ying Wang;  Guo-Chun Zhou
Favorite | View/Download:34/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2019/11/22
1h-pyrrolo[1,2-c]Imidazol-1-one  Vitamin d Receptor (Vdr)  Autophagy  Apoptosis  
Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2019,Volume: 27,Issue: 17,Page: 3879-3888
Authors:  Bin Xu;  Mo-Yu Ding;  Zhibing Weng;  Zheng-Qing Li;  Feng Li;  Xia Sun;  Qiu-Ling Chen;  Yi-Tao Wang;  Ying Wang;  Guo-Chun Zhou
Favorite | View/Download:9/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/05/05
1h-pyrrolo[1,2-c]Imidazol-1-one  Vitamin d Receptor (Vdr)  Autophagy  Apoptosis  
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018,Volume: 28,Issue: 21,Page: 3441-3445
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
Favorite | View/Download:19/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2018/10/30
Pyruvate dehydrogenase kinase  Pyruvate dehydrogenase complex  Antiproliferative activity  Dichloroacetophenone  Kinase inhibition  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View | Adobe PDF | Favorite | View/Download:1096/77 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Structure-activity relationships of cryptopleurine analogs with E-ring modifications as anti-hepatitis C virus agents Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 3,Page: 630-636
Authors:  Wang, Ying;  Chen, Shao-Ru;  Yang, Xiaoming;  Lee, Kuo-Hsiung;  Cheng, Yung-Chi
Favorite | View/Download:17/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2018/10/30
C-21-steroidal pregnane sapogenins and their derivatives as anti-inflammatory agents Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2017,Volume: 25,Issue: 13,Page: 3512-3524
Authors:  Huang, Lie-Jun;  Chen, Shao-Ru;  Yuan, Chun-Mao;  Gu, Wei;  Guo, Bao-Jian;  Wang, Yi-Tao;  Wang, Ying;  Hao, Xiao-Jiang
Favorite | View/Download:25/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2018/10/30
C21-steroidal Pregnane Steroids  Anti-inflammation  Tlr  Nf-kappa b  Traf6  
C21-steroidal pregnane sapogenins and their derivatives as anti-inflammatory agents Journal article
Bioorganic and Medicinal Chemistry, 2017,Volume: 25,Issue: 13,Page: 3512
Authors:  Huang L.-J.;  Chen S.-R.;  Yuan C.-M.;  Gu W.;  Guo B.-J.;  Wang Y.-T.;  Wang Y.;  Hao X.-J.
Favorite | View/Download:12/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2018/10/31
Anti-inflammation  C21-steroidal Pregnane Steroids  Nf-κb  Tlr  Traf6  
2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists Journal article
Bioorganic and Medicinal Chemistry, 2016,Volume: 24,Issue: 11,Page: 2530-2543
Authors:  Vergelli C.;  Schepetkin I.A.;  Ciciani G.;  Cilibrizzi A.;  Crocetti L.;  Giovannoni M.P.;  Guerrini G.;  Iacovone A.;  Kirpotina L.N.;  Khlebnikov A.I.;  Ye R.D.;  Quinn M.T.
Favorite | View/Download:6/0 | TC[WOS]:9 TC[Scopus]:0 | Submit date:2018/11/07
Agonist  Ca2+ mobilization  Formyl peptide receptor (FPR)  Neutrophil  Pyridazin-3(2H)-one  
Study the interactions between human serum albumin and two antifungal drugs: Fluconazole and its analogue DTP Journal article
Bioorganic and Medicinal Chemistry Letters, 2014,Volume: 24,Issue: 21,Page: 4963-4968
Authors:  Zhang S.-L.;  Yao H.;  Wang C.;  Tam K.Y.
Favorite | View/Download:3/0 | TC[WOS]:13 TC[Scopus]:0 | Submit date:2018/12/18
Binding Affinity  Fluconazole  Fluorescence Spectrum  Human Serum Albumin  Molecular Docking  
Identification and evaluation of apoptotic compounds from Garcinia oligantha Journal article
Bioorganic and Medicinal Chemistry Letters, 2012,Volume: 22,Issue: 6,Page: 2350-2353
Authors:  Gao X.-M.;  Yu T.;  Cui M.-Z.;  Pu J.-X.;  Du X.;  Han Q.-B.;  Hu Q.-F.;  Liu T.-C.;  Luo K.Q.;  Xu H.-X.
Favorite | View/Download:8/0 | TC[WOS]:28 TC[Scopus]:0 | Submit date:2018/12/18
Anticancer Drug  Apoptosis  Caspase-3  Garcinia Oligantha  Xanthone