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| Predicting the human jejunal permeability and fraction absorbed of fluoroquinolones based on a biophysical model Conference paper
Frontiers in Biomedical Engineering and Biotechnology, Beijing, China, 2014-9-25-28
Authors: Chenyin W.; Avdeef A.; Wen Z.; Tam K.Y.
  Favorite | View/Download：18/0 | TC[WOS]:2 TC[Scopus]:2 | Submit date：2018/12/18
Caco-2 Fluoroquinolones Fraction Absorbed Human Intestine Permeability |
| Predicting the exposure and antibacterial activity of fluoroquinolones based on physicochemical properties Journal article
European Journal of Pharmaceutical Sciences, 2012,Volume: 47,Issue: 1,Page: 21-27
Authors: Volgyi G.; Vizseralek G.; Takacs-Novak K.; Avdeef A.; Tam K.Y.
Favorite | View/Download：7/0 | TC[WOS]:24 TC[Scopus]:24 | Submit date：2018/12/18
Antimicrobial Activity Fluoroquinolones Mic Pampa Protonation Microconstants True Partition Coefficients |
| How well can the caco-2/madin-darby canine kidney models predict effective human jejunal permeability? Journal article
Journal of Medicinal Chemistry, 2010,Volume: 53,Issue: 9,Page: 3566-3584
Authors: Avdeef A.; Tam K.Y.
Favorite | View/Download：13/0 | TC[WOS]:65 TC[Scopus]:72 | Submit date：2018/12/18 |
| The permeation of amphoteric drugs through artificial membranes - An in combo absorption model based on paracellular and transmembrane permeability Journal article
Journal of Medicinal Chemistry, 2010,Volume: 53,Issue: 1,Page: 392-401
Authors: Tam K.Y.; Avdeef A.; Tsinman O.; Sun N.
Favorite | View/Download：3/0 | TC[WOS]:34 TC[Scopus]:35 | Submit date：2018/12/18 |
| PH-metric logP 11. pK(a) determination of water-insoluble drugs in organic solvent-water mixtures Journal article
Journal of Pharmaceutical and Biomedical Analysis, 1999,Volume: 20,Issue: 4,Page: 631-641
Authors: Avdeef A.; Box K.J.; Comer J.E.A.; Gilges M.; Hadley M.; Hibbert C.; Patterson W.; Tam K.Y.
Favorite | View/Download：10/0 | TC[WOS]:186 TC[Scopus]:191 | Submit date：2018/12/18
1,4-dioxane Acetonitrile Acid Dissociation Constants Dimethylformamide Dimethylsulfoxide Ethanol Ethylene Glycol Methanol Ph-metric Titration Pk(a) Tetrahydrofuran |
| pH-Metric logP 10. Determination of liposomal membrane-water partition coefficients of ionizable drugs Journal article
Pharmaceutical Research, 1998,Volume: 15,Issue: 2,Page: 209-215
Authors: Avdeef A.; Box K.J.; Comer J.E.A.; Hibbert C.; Tam K.Y.
Favorite | View/Download：7/0 | TC[WOS]:302 TC[Scopus]:320 | Submit date：2018/12/18
Drug-lipid Membrane Interaction Ionizable Drug Liposome Partition Coefficient |
