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9R, the cholinesterase and amyloid beta aggregation dual inhibitor, as a multifunctional agent to improve cognitive deficit and neuropathology in the triple-transgenic Alzheimer's disease mouse model Journal article
Neuropharmacology, 2020,Volume: 181
Authors:  Ju,Yaojun;  Tam,Kin Yip
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Alzheimer's disease  Amyloid beta  Cholinesterase  Dual inhibition  Multifunction  
An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease Journal article
ACS Chemical Neuroscience, 2020,Volume: 11,Issue: 20,Page: 3346-3357
Authors:  Ju,Yaojun;  Chakravarty,Harapriya;  Tam,Kin Yip
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Alzheimer's disease  amyloid beta  cholinesterase  dual inhibition  
Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives Journal article
Drug Development Research, 2020,Volume: 81,Issue: 2,Page: 242-255
Authors:  Chakravarty,Harapriya;  Ju,Yaojun;  Chen,Wen Hua;  Tam,Kin Y.
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acetylcholinesterase  Alzheimer's disease  amyloid beta  butyrylcholinesterase  dual target inhibitor  isoquinolinium  pyridinium  
Fish oil protects the blood-brain barrier integrity in a mouse model of Alzheimer's disease Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Xie,Youna;  Yan,Lingli;  Zeng,Haitao;  Chen,Weineng;  Lu,Jia Hong;  Wan,Jian Bo;  Su,Huanxing;  Yao,Xiaoli
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Amyloid beta  Aβ-degrading enzymes  Neuroinflammation  NF-κB  Omega-3 polyunsaturated fatty acids  
Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts Journal article
BMC complementary medicine and therapies, 2020,Volume: 20,Issue: 1
Authors:  Ardah,Mustafa T.;  Ghanem,Simona S.;  Abdulla,Sara A.;  Lv,Guohua;  Emara,Mohamed M.;  Paleologou,Katerina E.;  Vaikath,Nishant N.;  Lu,Jia Hong;  Li,Min;  Vekrellis,Konstantinos;  Eliezer,David;  El-Agnaf,Omar M.A.
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Amyloid fibrils  Dihydromyricetin  Parkinson’s disease  Salvianolic acid B  Seeded fibril formation  α-Synuclein  
Omega-3 polyunsaturated fatty acids promote brain-to-blood clearance of β-Amyloid in a mouse model with Alzheimer's disease Journal article
Brain, Behavior, and Immunity, 2020,Volume: 85,Page: 35-45
Authors:  Yan,Lingli;  Xie,Youna;  Satyanarayanan,Senthil Kumaran;  Zeng,Haitao;  Liu,Qiang;  Huang,Miaodan;  Ma,Yuemeng;  Wan,Jian Bo;  Yao,Xiaoli;  Su,Kuan Pin;  Su,Huanxing
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Alzheimer's disease  beta-Amyloid  Low-density lipoprotein receptor-related protein 1  Neuroinflammation  Omega-3 polyunsaturated fatty acids  
A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models Journal article
Aging Cell, 2020,Volume: 19,Issue: 2
Authors:  Song,Ju Xian;  Malampati,Sandeep;  Zeng,Yu;  Durairajan,Siva Sundara Kumar;  Yang,Chuan Bin;  Tong,Benjamin Chun Kit;  Iyaswamy,Ashok;  Shang,Wen Bin;  Sreenivasmurthy,Sravan Gopalkrishnashetty;  Zhu,Zhou;  Cheung,King Ho;  Lu,Jia Hong;  Tang,Chunzhi;  Xu,Nenggui;  Li,Min
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Alzheimer's disease  beta-amyloid  curcumin analog C1  MAPT/Tau  TFEB  
Artemisinin improved neuronal functions in Alzheimer's disease animal model 3xtg mice and neuronal cells via stimulating the ERK/CREB signaling pathway Journal article
Aging and Disease, 2020,Volume: 11,Issue: 4,Page: 801-819
Authors:  Zhao,Xia;  Li,Shuai;  Gaur,Uma;  Zheng,Wenhua
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3×Tg mice  Alzheimer's disease  Amyloid beta  Artemisinin  Cognitive behavior  SH-SY5Ycells  
The effects of bioactive components from the rhizome of Salvia miltiorrhiza (Danshen) on the characteristics of Alzheimer's disease Journal article
Chinese Medicine, 2019,Volume: 14
Authors:  Cheong‑Meng Chong;  Huanxing Su;  Jin‑Jian Lu;  Yitao Wang
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Alzheimer’s Disease  Danshen  Amyloid β Plaques  Neurofbrillary Tangles  Mitochondrial Dysfunction  Autophagy  
The effects of bioactive components from the rhizome of Salvia miltiorrhiza(Danshen) on the characteristics of Alzheimer’s disease Journal article
CHINESE MEDICINE, 2019
Authors:  Cheong‑Meng Chong;  Huanxing Su;  Jin‑Jian Lu;  Yitao Wang
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Alzheimer’s Disease  Amyloid β Plaques  Neurofibrillary Tangles  Mitochondrial Dysfunction  Autophagy  Danshen