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9R, the cholinesterase and amyloid beta aggregation dual inhibitor, as a multifunctional agent to improve cognitive deficit and neuropathology in the triple-transgenic Alzheimer's disease mouse model Journal article
Neuropharmacology, 2020,Volume: 181
Authors:  Ju,Yaojun;  Tam,Kin Yip
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Alzheimer's disease  Amyloid beta  Cholinesterase  Dual inhibition  Multifunction  
The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review Journal article
Phytomedicine, 2020,Volume: 79
Authors:  Zhang,Shuang;  Zhu,Qi;  Chen,Jia Yue;  OuYang,Defang;  Lu,Jia Hong
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AD animal models  Alzheimer's disease  Clinical trials  EGCG  Neuroprotective effects  Systematic review  
Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer’s Disease Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Iyaswamy,A.;  Krishnamoorthi,S. K.;  Liu,Y. W.;  Song,J. X.;  Kammala,A. K.;  Sreenivasmurthy,S. G.;  Malampati,S.;  Tong,B. C.K.;  Selvarasu,K.;  Cheung,K. H.;  Lu,J. H.;  Tan,J. Q.;  Huang,C. Y.;  Durairajan,S. S.K.;  Li,M.
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Alzheimer’s disease  Chinese medicine  connectivity map  microarray  neurofibrillary tangles  P301S tau mice  yuan-hu zhi tong  
An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease Journal article
ACS Chemical Neuroscience, 2020,Volume: 11,Issue: 20,Page: 3346-3357
Authors:  Ju,Yaojun;  Chakravarty,Harapriya;  Tam,Kin Yip
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Alzheimer's disease  amyloid beta  cholinesterase  dual inhibition  
Shexiang Baoxin Pill, a Traditional Chinese Herbal Formula, Rescues the Cognitive Impairments in APP/PS1 Transgenic Mice Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Hu,Wei Hui;  Mak,Shing Hung;  Zheng,Zhong Yu;  Xia,Ying Jie;  Xu,Miranda Li;  Duan,Ran;  Dong,Tina Ting Xia;  Li,Shao Ping;  Zhan,Chang Sen;  Shang,Xiao Hui;  Tsim,Karl Wah Keung
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acetylcholinesterase  Alzheimer’s disease  Chinese medicine  cognitive enhancing effect  neuroprotective  Shexiang Baoxin Pill  
Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives Journal article
Drug Development Research, 2020,Volume: 81,Issue: 2,Page: 242-255
Authors:  Chakravarty,Harapriya;  Ju,Yaojun;  Chen,Wen Hua;  Tam,Kin Y.
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acetylcholinesterase  Alzheimer's disease  amyloid beta  butyrylcholinesterase  dual target inhibitor  isoquinolinium  pyridinium  
A Systematic Bioinformatics Workflow With Meta-Analytics Identified Potential Pathogenic Factors of Alzheimer’s Disease Journal article
Frontiers in Neuroscience, 2020,Volume: 14
Authors:  Yuen,Sze Chung;  Zhu,Hongmei;  Leung,Siu Wai
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Alzheimer’s disease  bioinformatics  meta-analysis  microarray analysis  RNA sequence analysis  
Omega-3 polyunsaturated fatty acids promote brain-to-blood clearance of β-Amyloid in a mouse model with Alzheimer's disease Journal article
Brain, Behavior, and Immunity, 2020,Volume: 85,Page: 35-45
Authors:  Yan,Lingli;  Xie,Youna;  Satyanarayanan,Senthil Kumaran;  Zeng,Haitao;  Liu,Qiang;  Huang,Miaodan;  Ma,Yuemeng;  Wan,Jian Bo;  Yao,Xiaoli;  Su,Kuan Pin;  Su,Huanxing
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Alzheimer's disease  beta-Amyloid  Low-density lipoprotein receptor-related protein 1  Neuroinflammation  Omega-3 polyunsaturated fatty acids  
A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models Journal article
Aging Cell, 2020,Volume: 19,Issue: 2
Authors:  Song,Ju Xian;  Malampati,Sandeep;  Zeng,Yu;  Durairajan,Siva Sundara Kumar;  Yang,Chuan Bin;  Tong,Benjamin Chun Kit;  Iyaswamy,Ashok;  Shang,Wen Bin;  Sreenivasmurthy,Sravan Gopalkrishnashetty;  Zhu,Zhou;  Cheung,King Ho;  Lu,Jia Hong;  Tang,Chunzhi;  Xu,Nenggui;  Li,Min
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Alzheimer's disease  beta-amyloid  curcumin analog C1  MAPT/Tau  TFEB  
Quercetin in animal models of Alzheimer’s disease: A systematic review of preclinical studies Journal article
International Journal of Molecular Sciences, 2020,Volume: 21,Issue: 2
Authors:  Zhang,Xiao Wen;  Chen,Jia Yue;  Ouyang,Defang;  Lu,Jia Hong
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Alzheimer’s disease  Animal AD models  Neuroprotective effects  Quercetin