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In vitro and in vivo structure and activity relationship analysis of polymethoxylated flavonoids: Identifying sinensetin as a novel antiangiogenesis agent Journal article
Molecular Nutrition and Food Research, 2012,Volume: 56,Issue: 6,Page: 945
Authors:  Lam I.K.;  Alex D.;  Wang Y.-H.;  Liu P.;  Liu A.-L.;  Du G.-H.;  Yuen Lee S.M.
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Angiogenesis  Polymethoxylated Flavonoid  Sinensetin  Structure-activity Relationship  Zebrafish  
Inhibition of TNF-α-mediated endothelial cell-monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans-3,5,4′-trimethoxystilbene Journal article
Phytotherapy Research, 2011,Volume: 25,Issue: 3,Page: 451
Authors:  Deng Y.-H.;  Alex D.;  Huang H.-Q.;  Wang N.;  Yu N.;  Wang Y.-T.;  Leung G.P.H.;  Lee S.M.-Y.
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Cell Adhesion Molecules  Inflammation  Nf-′b  Resveratrol  Stilbene  
Nobiletin, a polymethoxylated flavonoid from citrus, shows anti-angiogenic activity in a zebrafish in vivo model and HUVEC in vitro model Journal article
Journal of Cellular Biochemistry, 2011,Volume: 112,Issue: 11,Page: 3313
Authors:  Lam K.H.;  Alex D.;  Lam I.K.;  Tsui S.K.W.;  Yang Z.F.;  Lee S.M.Y.
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Angiogenesis  Anti-inflammatory  Cell Cycle  Flavonoid  Nobiletin  Zebrafish  
Calycosin promotes angiogenesis involving estrogen receptor and mitogen-activated protein kinase (MAPK) signaling pathway in zebrafish and HUVEC Journal article
PLoS ONE, 2010,Volume: 5,Issue: 7
Authors:  Tang J.Y.;  Li S.;  Li Z.H.;  Zhang Z.J.;  Hu G.;  Cheang L.C.V.;  Alex D.;  Hoi M.P.M.;  Kwan Y.W.;  Chan S.W.;  Leung G.P.H.;  Lee S.M.Y.
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Resveratrol derivative, trans-3,5,4′-trimethoxystilbene, exerts antiangiogenic and vascular-disrupting effects in zebrafish through the downregulation of VEGFR2 and cell-cycle modulation Journal article
Journal of Cellular Biochemistry, 2010,Volume: 109,Issue: 2,Page: 339
Authors:  Alex D.;  Leong E.C.;  Zhang Z.-J.;  Yan G.T.H.;  Cheng S.-H.;  Leong C.-W.;  Li Z.-H.;  Lam K.-H.;  Chan S.-W.;  Lee S.M.-Y.
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3,5,4′-trimethoxystilbene  Angiogenesis  Cell Cycle  Huvec  Vegfr2  Zebrafish  
Indirubin shows anti-angiogenic activity in an in vivo zebrafish model and an in vitro HUVEC model Journal article
Journal of Ethnopharmacology, 2010,Volume: 131,Issue: 2,Page: 242
Authors:  Alex D.;  Lam I.K.;  Lin Z.;  Lee S.M.Y.
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Anti-angiogenesis  Apoptosis  Indirubin  Zebrafish