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Development of a Highly Water-Soluble Lycopene Cyclodextrin Ternary Formulation by the Integrated Experimental and Modeling Techniques Journal article
AAPS PharmSciTech, 2021,Volume: 22,Issue: 1
Authors:  Ma,Yan;  Zhong,Liuting;  Peng,Zhuo;  Liu,Xinyang;  Ouyang,Defang;  Guan,Shixia
Favorite | View/Download:0/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
bioavailability  hot-melt extrusion  lycopene  molecular dynamics simulation  ternary formulation  
Insight into the Dissolution Molecular Mechanism of Ternary Solid Dispersions by Combined Experiments and Molecular Simulations Journal article
AAPS PHARMSCITECH, 2019,Volume: 20,Issue: 7
Authors:  Run Han;  Tianhe Huang;  Xinyang Liu;  Xinyang Liu;  Haifeng Li;  Jiahong Lu;  Yuanhui Ji;  Huimin Sun;  Defang Ouyang
Favorite | View/Download:18/0 | TC[WOS]:4 TC[Scopus]:3 | Submit date:2020/03/25
Solid Dispersion  Dissolution Effect  Molecular Modeling  Ternary System  
Release Mechanism Between Ion Osmotic Pressure and Drug Release in Ionic-Driven Osmotic Pump Tablets (I) Journal article
AAPS PHARMSCITECH, 2018,Volume: 19,Issue: 2,Page: 803-811
Authors:  Cheng, Lizhen;  Gao, Siqi;  Ouyang, Defang;  Wang, Haiying;  Wang, Yongfei;  Pan, Weisan;  Yang, Xinggang
Favorite | View/Download:28/0 | TC[WOS]:2 TC[Scopus]:2 | Submit date:2018/10/30
Release Mechanism  Ionic-driven Osmotic Pump  Ionic Osmotic Pressure  Zero-order Kinetic Model  Formula Verification  Ivivc  
Pluronic F68-Linoleic Acid Nano-spheres Mediated Delivery of Gambogic Acid for Cancer Therapy Journal article
AAPS PHARMSCITECH, 2017,Volume: 18,Issue: 1,Page: 147-155
Authors:  Fang, Xiaobin;  Xu, Yingqi;  Wang, Shengpeng;  Wan, Jianbo;  He, Chengwei;  Chen, Meiwan
Favorite | View/Download:35/0 | TC[WOS]:8 TC[Scopus]:8 | Submit date:2018/10/30
Anticancer  Gambogic Acid  Linoleic Acid  Nano-spheres  Pluronic F68  
Design and Evaluation of Hydrophilic Matrix System Containing Polyethylene Oxides for the Zero-Order Controlled Delivery of Water-Insoluble Drugs Journal article
AAPS PHARMSCITECH, 2017,Volume: 18,Issue: 1,Page: 82-92
Authors:  Wang, Lijie;  Chen, Kai;  Wen, Haoyang;  Ouyang, Defang;  Li, Xue;  Gao, Yunyun;  Pan, Weisan;  Yang, Xinggang
Favorite | View/Download:23/0 | TC[WOS]:12 TC[Scopus]:13 | Submit date:2018/10/30
Hydrophilic Matrix System  Polyethylene Oxides  Water Insoluble Drug  In Vitro Release  Viscosity  
Development and characterisation of ursolic acid nanocrystals without stabiliser having improved dissolution rate and in vitro anticancer activity Journal article
AAPS PharmSciTech, 2014,Volume: 15,Issue: 1,Page: 11
Authors:  Song Ju.;  Wang Y.;  Song Y.;  Chan H.;  Bi C.;  Yang X.;  Yan R.;  Wang Y.;  Zheng Y.
Favorite | View/Download:7/0 | TC[WOS]:26 TC[Scopus]:28 | Submit date:2018/10/30
Anticancer  Dissolution  Mcf-7  Nanocrystals  Ursolic Acid  
Influence of processing parameters and formulation factors on the bioadhesive, temperature stability and drug release properties of hot-melt extruded films containing miconazole Journal article
AAPS PharmSciTech, 2014,Volume: 15,Issue: 3,Page: 522-529
Authors:  Chen M.;  Lu J.;  Deng W.;  Singh A.;  Mohammed N.N.;  Repka M.A.;  Wu C.
Favorite | View/Download:7/0 | TC[WOS]:11 TC[Scopus]:11 | Submit date:2018/12/27
bioadhesive properties  formulation factors  processing parameters  release studies  stability properties  
Enhancing the antitumor activity of berberine hydrochloride by solid lipid nanoparticle encapsulation Journal article
AAPS PharmSciTech, 2014,Volume: 15,Issue: 4,Page: 834
Authors:  Wang L.;  Li H.;  Wang S.;  Liu R.;  Wu Z.;  Wang C.;  Wang Y.;  Chen M.
Favorite | View/Download:17/0 | TC[WOS]:42 TC[Scopus]:44 | Submit date:2018/10/30
Antitumor Evaluation  Apoptosis  Berberine Hydrochloride  Solid Lipid Nanoparticles  
Molecular modeling-based inclusion mechanism and stability studies of doxycycline and hydroxypropyl-β-cyclodextrin complex for ophthalmic delivery Journal article
AAPS PharmSciTech, 2013,Volume: 14,Issue: 1,Page: 10
Authors:  Zhang H.;  Chen M.;  He Z.;  Wang Z.;  Zhang M.;  He Z.;  Wan Q.;  Liang D.;  Repka M.A.;  Wu C.
Favorite | View/Download:21/0 | TC[WOS]:12 TC[Scopus]:14 | Submit date:2018/10/30
doxycycline  hydroxypropyl-β-cyclodextrin  inclusion mechanism  molecular modeling  stability  
Development of amphotericin B-loaded cubosomes through the SolEmuls technology for enhancing the oral bioavailability Journal article
AAPS PharmSciTech, 2012,Volume: 13,Issue: 4,Page: 1483-1491
Authors:  Yang Z.;  Tan Y.;  Chen M.;  Dian L.;  Shan Z.;  Peng X.;  Wu C.
Favorite | View/Download:12/0 | TC[WOS]:46 TC[Scopus]:48 | Submit date:2018/12/27
amphotericin B  cubosomes  oral bioavailability  SolEmuls technology