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Diethyl blechnic, a novel natural product isolated from salvia miltiorrhiza bunge, inhibits doxorubicin-induced apoptosis by inhibiting ROS and activating JNK1/2 Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
Authors:  Yu J.;  Gao H.;  Wu C.;  Xu Q.-M.;  Lu J.-J.;  Chen X.
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Cardiotoxicity  Diethyl blechnic  DOX  JNK1/2  ROS  
Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells Journal article
FREE RADICAL BIOLOGY AND MEDICINE, 2017,Volume: 108,Page: 433-444
Authors:  Sun, Wen;  Wu, Xiaxia;  Gao, Hongwei;  Yu, Jie;  Zhao, Wenwen;  Lu, Jin-Jian;  Wang, Jinhua;  Du, Guanhua;  Chen, Xiuping
Favorite  |  View/Download:3/0  |  Submit date:2018/10/30
Necroptosis  c-Jun N-terminal kinase  Calcium  ROS  
Dihydrotanshinone I attenuates atherosclerosis in ApoE-deficient mice: Role of NOX4/NF-κB mediated lectin-like oxidized LDL receptor-1 (LOX-1) of the Endothelium Journal article
Frontiers in Pharmacology, 2016,Volume: 7,Issue: NOV
Authors:  Zhao W.;  Li C.;  Gao H.;  Wu Q.;  Shi J.;  Chen X.
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Atherosclerosis  Dihydrotanshinone I  Lipopolysaccharide  LOX-1  ROS  
Cryptotanshinone inhibits TNF-α-induced LOX-1 expression by suppressing reactive oxygen species (ROS) formation in endothelial cells Journal article
Korean Journal of Physiology and Pharmacology, 2016,Volume: 20,Issue: 4,Page: 347-355
Authors:  Ran X.;  Zhao W.;  Li W.;  Shi J.;  Chen X.
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Cryptotanshinone  Endothelial cells  LOX-1  ROS  TNF-α  
Cryptotanshinone inhibits oxidized LDL-induced adhesion molecule expression via ROS dependent NF-κB pathways Journal article
Cell Adhesion and Migration, 2016,Volume: 10,Issue: 3,Page: 248-258
Authors:  Zhao W.;  Wu C.;  Chen X.
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Cryptotanshinone  Endothelial cells  Endothelial dysfunction  Ox-LDL  ROS  
2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells Journal article
Free Radical Biology and Medicine, 2016,Volume: 92,Page: 61-77
Authors:  Sun W.;  Bao J.;  Lin W.;  Gao H.;  Zhao W.;  Zhang Q.;  Leung C.-H.;  Ma D.-L.;  Lu J.;  Chen X.
Favorite  |  View/Download:0/0  |  Submit date:2018/11/06
Apoptosis  Cancer  MAM  Necroptosis  NO  ROS  
Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells Journal article
Journal of Natural Medicines, 2015,Volume: 69,Issue: 4,Page: 522-530
Authors:  Ren G.;  Sha T.;  Guo J.;  Li W.;  Lu J.;  Chen X.
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Autophagy  Breast cancer  Cucurbitacin B  DNA damage  ROS  
Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in leukemia K562 cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2014,Volume: 14,Issue: 8,Page: 1146-1153
Authors:  Guo J.;  Zhao W.;  Hao W.;  Ren G.;  Lu J.;  Chen X.
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Apoptosis  Cancer  Cucurbitacin B  DNA damage  G2/M arrest  ROS  
Psoralidin induces autophagy through ROS generation which inhibits the proliferation of human lung cancer A549 cells Journal article
PeerJ, 2014,Volume: 2014,Issue: 1
Authors:  Hao W.;  Zhang X.;  Zhao W.;  Chen X.
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Autophagy  Cancer  Psoralidin  ROS  
Lipopolysaccharide induced LOX-1 expression via TLR4/MyD88/ROS activated p38MAPK-NF-κB pathway Journal article
Vascular Pharmacology, 2014,Volume: 63,Issue: 3,Page: 162
Authors:  Zhao W.;  Ma G.;  Chen X.
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Endothelial cells  Lipopolysaccharide  LOX-1  ROS