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2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells Journal article
Free Radical Biology and Medicine, 2016,Volume: 92,Page: 61-77
Authors:  Sun W.;  Bao J.;  Lin W.;  Gao H.;  Zhao W.;  Zhang Q.;  Leung C.-H.;  Ma D.-L.;  Lu J.;  Chen X.
Favorite  |  View/Download:0/0  |  Submit date:2018/11/06
Apoptosis  Cancer  MAM  Necroptosis  NO  ROS  
Cucurbitacin e induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells Journal article
Chemico-Biological Interactions, 2016,Volume: 253,Page: 1
Authors:  Ma G.;  Luo W.;  Lu J.;  Ma D.-L.;  Leung C.-H.;  Wang Y.;  Chen X.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/31
Apoptosis  Autophagy  Cancer  Cucurbitacin e  Reactive Oxygen Species  
Cryptotanshinone induces pro-death autophagy through JNK signaling mediated by reactive oxygen species generation in lung cancer cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2016,Volume: 16,Issue: 5,Page: 593
Authors:  Hao W.;  Zhang X.;  Zhao W.;  Zhu H.;  Liu Z.-Y.;  Lu J.;  Chen X.
Favorite  |  View/Download:0/0  |  Submit date:2018/10/30
Autophagy  Cancer  Cryptotanshinone  JNK  Reactive oxygen species  
Saponins from Chinese Medicines as Anticancer Agents Journal article
Molecules, 2016,Volume: 21,Issue: 10,Page: 1326
Authors:  Xu XH;  Li T;  Fong CMV;  Chen XP;  Chen XJ;  Wang YT;  Huang MQ;  Lu JJ
Favorite  |  View/Download:2/0  |  Submit date:2018/11/23
Triterpenoid Saponins  Steroid Saponins  Mechanism  Target  Cancer  
The human Nox4: gene, structure, physiological function and pathological significance Journal article
Journal of Drug Targeting, 2015,Volume: 23,Issue: 10,Page: 888-896
Authors:  Shuhui Guo;  Xiuping Chen
Favorite  |  View/Download:0/0  |  Submit date:2019/01/07
Cancer  Cardiovascular Diseases  Hydrogen Peroxides  Nox4  Ros  
Natural autophagy regulators in cancer therapy: a review Journal article
Phytochemistry Reviews, 2015,Volume: 14,Issue: 1,Page: 137-154
Authors:  Qian Ding;  Jiaolin Bao;  Wenwen Zhao;  Yangyang Hu;  Jinjian Lu;  Xiuping Chen
Favorite  |  View/Download:0/0  |  Submit date:2019/01/07
Autophagy  Cancer  Natural Products  Drug Discovery  
Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in leukemia K562 cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2014,Volume: 14,Issue: 8,Page: 1146-1153
Authors:  Guo J.;  Zhao W.;  Hao W.;  Ren G.;  Lu J.;  Chen X.
Favorite  |  View/Download:0/0  |  Submit date:2018/12/28
Apoptosis  Cancer  Cucurbitacin B  DNA damage  G2/M arrest  ROS  
Platycodin D induces apoptosis, and inhibits adhesion, migration and invasion in HepG2 hepatocellular carcinoma cells Journal article
Asian Pacific Journal of Cancer Prevention, 2014,Volume: 15,Issue: 4,Page: 1745
Authors:  Li T.;  Xu W.-S.;  Wu G.-S.;  Chen X.-P.;  Wang Y.-T.;  Lu J.-J.
Favorite  |  View/Download:5/0  |  Submit date:2018/10/30
Apoptosis  Cancer  Hepg2  Metastasis  Platycodin d  
The Anticancer Properties of Salvia Miltiorrhiza Bunge (Danshen): A Systematic Review Journal article
Medicinal Research Reviews, 2014,Volume: 34,Issue: 4,Page: 768
Authors:  Chen X.;  Guo J.;  Bao J.;  Lu J.;  Wang Y.
Favorite  |  View/Download:3/0  |  Submit date:2018/10/30
Cancer  Derivatives  Phenolic Acids  Salvia Miltiorrhiza Bunge  Tanshinones  
Psoralidin induces autophagy through ROS generation which inhibits the proliferation of human lung cancer A549 cells Journal article
PeerJ, 2014,Volume: 2014,Issue: 1
Authors:  Hao W.;  Zhang X.;  Zhao W.;  Chen X.
Favorite  |  View/Download:0/0  |  Submit date:2018/10/30
Autophagy  Cancer  Psoralidin  ROS