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MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation Journal article
Apoptosis, 2018,Volume: 23,Issue: 9-10,Page: 521-531
Authors:  Cao W.-X.;  Li T.;  Tang Z.-H.;  Zhang L.-L.;  Wang Z.-Y.;  Guo X.;  Su M.-X.;  Chen X.;  Lu J.-J.
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Apoptosis  Chelerythrine  eIF2α  MLKL  ROS  
Diethyl blechnic, a novel natural product isolated from salvia miltiorrhiza bunge, inhibits doxorubicin-induced apoptosis by inhibiting ROS and activating JNK1/2 Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
Authors:  Yu J.;  Gao H.;  Wu C.;  Xu Q.-M.;  Lu J.-J.;  Chen X.
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Cardiotoxicity  Diethyl blechnic  DOX  JNK1/2  ROS  
Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells Journal article
REDOX BIOLOGY, 2017,Volume: 12,Page: 367-376
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Wang, Zhao-Yu;  Lu, Jia-Hong;  Liu, Bo;  Chen, Xiuping;  Lu, Jin-Jian
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Chelerythrine  Autophagy  Apoptosis  ROS  NSCLC  
Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells Journal article
FREE RADICAL BIOLOGY AND MEDICINE, 2017,Volume: 108,Page: 433-444
Authors:  Sun, Wen;  Wu, Xiaxia;  Gao, Hongwei;  Yu, Jie;  Zhao, Wenwen;  Lu, Jin-Jian;  Wang, Jinhua;  Du, Guanhua;  Chen, Xiuping
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Necroptosis  c-Jun N-terminal kinase  Calcium  ROS  
Osimertinib induces autophagy and apoptosis via reactive oxygen species generation in non-small cell lung cancer cells Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 321,Page: 18-26
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
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Osimertinib  AZD9291  Autophagy  Apoptosis  ROS  
Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells Journal article
Journal of Natural Medicines, 2015,Volume: 69,Issue: 4,Page: 522-530
Authors:  Ren G.;  Sha T.;  Guo J.;  Li W.;  Lu J.;  Chen X.
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Autophagy  Breast cancer  Cucurbitacin B  DNA damage  ROS  
Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in leukemia K562 cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2014,Volume: 14,Issue: 8,Page: 1146-1153
Authors:  Guo J.;  Zhao W.;  Hao W.;  Ren G.;  Lu J.;  Chen X.
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Apoptosis  Cancer  Cucurbitacin B  DNA damage  G2/M arrest  ROS