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Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model Journal article
Molecular Therapy - Nucleic Acids, 2018,Volume: 13,Page: 291-302
Authors:  Luo F.;  Xie Y.;  Wang Z.;  Huang J.;  Tan Q.;  Sun X.;  Li F.;  Li C.;  Liu M.;  Zhang D.;  Xu M.;  Su N.;  Ni Z.;  Jiang W.;  Chang J.;  Chen H.;  Chen S.;  Xu X.;  Deng C.;  Wang Z.;  Du X.;  Chen L.
Favorite  |  View/Download:13/0  |  Submit date:2018/12/13
Adeno-associated Virus  Apert Syndrome  Craniosynostosis  Fgfr2  Molecular Therapy  Rnai  
Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation Journal article
JOURNAL OF BONE AND MINERAL RESEARCH, 2017,Volume: 32,Issue: 11,Page: 2194-2206
Authors:  Xu, Wei;  Luo, Fengtao;  Wang, Quan;  Tan, Qiaoyan;  Huang, Junlan;  Zhou, Siru;  Wang, Zuqiang;  Sun, Xianding;  Kuang, Liang;  Jin, Min;  Su, Nan;  Jiang, Wanling;  Chen, Liang;  Qi, Huabing;  Zhu, Ying;  Chen, Bo;  Chen, Hangang;  Chen, Shuai;  Gao, Yu;  Xu, Xiaoling;  Deng, Chuxia;  Chen, Lin;  Xie, Yangli;  Du, Xiaolan
Favorite  |  View/Download:14/0  |  Submit date:2018/10/30
Bone Marrow Ablation  Fgfr2  Bone Formation  Wnt/beta-catenin  
Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2017,Volume: 13,Issue: 9,Page: 1163-1171
Authors:  Lei, Haipeng;  Deng, Chu-Xia
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Breast Cancer  Fgfr2  Mutation  Polymorphism  Inhibitor  
Early onset of craniosynostosis in an Apert mouse model reveals critical features of this pathology Journal article
Developmental Biology, 2009,Volume: 328,Issue: 2,Page: 273-284
Authors:  Holmes G.;  Rothschild G.;  Roy U.B.;  Deng C.-X.;  Mansukhani A.;  Basilico C.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/13
Apert Syndrome  Calvaria  Coronal Suture  Craniosynostosis  Fgfr2  Intramembranous Ossification  Mouse  Osteoblast  
RNAi in mice: a promising approach to decipher gene functions in vivo Journal article
Biochimie, 2006,Volume: 88,Issue: 6,Page: 637-643
Authors:  Xavier Coumoul;  Chu-Xia Deng
Favorite  |  View/Download:7/0  |  Submit date:2018/12/18
Rnai  Fgfr2  Cre-loxp  Knockdown  Mice  
A Ser250Trp substitution in mouse fibroblast growth factor receptor 2 (Fgfr2) results in craniosynostosis Journal article
Bone, 2003,Volume: 33,Issue: 2,Page: 169-178
Authors:  Chen L.;  Li D.;  Li C.;  Engel A.;  Deng C.-X.
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Apert Syndrome  Apoptosis  Coronal Suture  Fgfr2  Intramembraneous Ossification  Proliferation  
Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning Journal article
Developmental Dynamics, 2001,Volume: 222,Issue: 3,Page: 471-483
Authors:  Li C.;  Guo H.;  Xu X.;  Weinberg W.;  Deng C.-X.
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Cell Proliferation  Fgfr2  Morphogenetic Transition  Mouse  Organogenesis  
Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction Journal article
Development, 1998,Volume: 125,Issue: 4,Page: 753-765
Authors:  Xu X.;  Weinstein M.;  Li C.;  Naski M.;  Cohen R.I.;  Ornitz D.M.;  Leder P.;  Deng C.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/13
Chorioallantoic Fusion  Fgf10 Expression  Fgf8 Induction  Fgfr2  Limb Bud Initiation  Placentation