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Inhibition of Estrogen Signaling Reduces the Incidence of BRCA1-associated Mammary Tumor Formation Journal article
International journal of biological sciences, 2018,Volume: 14,Issue: 12,Page: 1755-1768
Authors:  Baek H.J.;  Kim S.E.;  Choi E.K.;  Kim J.K.;  Shin D.H.;  Park E.J.;  Kim T.H.;  Kim J.-Y.;  Kim K.G.;  Deng C.-X.;  Kim S.S.
Favorite | View/Download:12/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2018/12/13
Brca1  Cancer Prevention  Estrogen  Fulvestrant  
Inhibition of AKT suppresses the initiation and progression of BRCA1-associated mammary tumors Journal article
International journal of biological sciences, 2018,Volume: 14,Issue: 13,Page: 1769-1781
Authors:  Baek H.J.;  Kim S.E.;  Kim J.K.;  Shin D.H.;  Kim T.H.;  Kim K.G.;  Deng C.-X.;  Kim S.S.
Favorite | View/Download:11/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/12/13
Akt  Brca1  Mk-2206  Precision Medicine  
“DNA binding region“ of BRCA1 affects genetic stability through modulating the intra-S-phase checkpoint Journal article
International Journal of Biological Sciences, 2016,Volume: 12,Issue: 2,Page: 133-143
Authors:  Masuda T.;  Xu X.;  Dimitriadis E.K.;  Lahusen T.;  Deng C.-X.
Favorite | View/Download:13/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/12/13
Brca1  Dna Binding  Genomic Instability  Intra-s-phase Checkpoint  
Damage-induced BRCA1 phosphorylation by Chk2 contributes to the timing of end resection Journal article
Cell Cycle, 2015,Volume: 14,Issue: 3,Page: 437-448
Authors:  Parameswaran B.;  Chiang H.-C.;  Lu Y.;  Coates J.;  Deng C.-X.;  Baer R.;  Lin H.-K.;  Li R.;  Paull T.T.;  Hu Y.
Favorite | View/Download:5/0 | TC[WOS]:15 TC[Scopus]:0 | Submit date:2018/12/13
Brca1  Cell Cycle  Dna Double-strand Break Repair  End-resection  Scf  
Mouse models of BRCA1 and their application to breast cancer research Journal article
Cancer and Metastasis Reviews, 2013,Volume: 32,Issue: 1-2,Page: 25-37
Authors:  Dine J.;  Deng C.-X.
Favorite | View/Download:6/0 | TC[WOS]:25 TC[Scopus]:0 | Submit date:2018/12/13
Brca1  Breast Cancer  Disease Mechanism  Modeling  Therapy  
Yin Yang 1 positively regulates BRCA1 and inhibits mammary cancer formation Journal article
Oncogene, 2012,Volume: 31,Issue: 1,Page: 116-127
Authors:  Lee M.-H.;  Lahusen T.;  Wang R.-H.;  Xiao C.;  Xu X.;  Hwang Y.-S.;  He W.-W.;  Shi Y.;  Deng C.-X.
Favorite | View/Download:6/0 | TC[WOS]:30 TC[Scopus]:0 | Submit date:2018/12/13
Brca1  Breast Cancer  Nude Mice  Promoter  Yy1  
Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1 Journal article
Oncogene, 2010,Volume: 29,Issue: 50,Page: 6603-6608
Authors:  Deng Y.;  Liu J.;  Han G.;  Lu S.-L.;  Wang S.-Y.;  Malkoski S.;  Tan A.C.;  Deng C.;  Wang X.-J.;  Zhang Q.
Favorite | View/Download:6/0 | TC[WOS]:25 TC[Scopus]:0 | Submit date:2018/12/13
Brca1  Ctbp1  Hnscc  Nadh  Transcription  Tumor Suppressor  
BRCA1 affects global DNA methylation through regulation of DNMT1 Journal article
Cell Research, 2010,Volume: 20,Issue: 11,Page: 1201-1215
Authors:  Shukla V.;  Coumoul X.;  Lahusen T.;  Wang R.-H.;  Xu X.;  Vassilopoulos A.;  Xiao C.;  Lee M.-H.;  Man Y.-G.;  Ouchi M.;  Ouchi T.;  Deng C.-X.
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Brca1  Histone Modification  Dna Methylation  Dnmt1  Genomic Imprinting  Tumor Formation  
Crosstalk between the DNA damage response, histone modifications and neovascularisation Journal article
The International Journal of Biochemistry & Cell Biology, 2010,Volume: 42,Issue: 2,Page: 193-197
Authors:  Athanassios Vassilopoulos;  Chu-Xia Deng;  Triantafyllos Chavakis
Favorite | View/Download:9/0 | TC[WOS]:9 TC[Scopus]:0 | Submit date:2018/12/17
Γ-h2ax  Angiogenesis  Brca1  Sirtuins  
BP1, an isoform of DLX4 homeoprotein, negatively regulates BRCA1 in sporadic breast cancer Journal article
International Journal of Biological Sciences, 2010,Volume: 6,Issue: 5,Page: 513-524
Authors:  Kluk B.J.;  Fu Y.;  Formolo T.A.;  Zhang L.;  Hindle A.K.;  Man Y.-G.;  Siegel R.S.;  Berg P.E.;  Deng C.;  McCaffrey T.A.;  Fu S.W.
Favorite | View/Download:5/0 | TC[WOS]:12 TC[Scopus]:0 | Submit date:2018/12/13
Bp1  Brca1  Breast Cancer  Dlx4  Homeoprotein