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TNF receptor type II as an emerging drug target for the treatment of cancer, autoimmune diseases, and graft-versus-host disease: Current perspectives and in silico search for small molecule binders Journal article
Frontiers in Immunology, 2018,Volume: 9,Issue: JUN
Authors:  Shaikh F.;  He J.;  Bhadra P.;  Chen X.;  Siu S.W.
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Drug discovery  MM-PBSA  Regulatory T cells  TNF  TNF receptor type II  Virtual screening  
Identification of novel natural compound inhibitors for human complement component 5a receptor by homology modeling and virtual screening Journal article
Medicinal Chemistry Research, 2016,Volume: 25,Issue: 8,Page: 1564-1573
Authors:  Shaikh F.;  Siu S.W.I.
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C5aR  Homology modeling  MM-GBSA  Molecular docking  Natural compound inhibitor  Virtual screening  
Recent Advances in the Discovery and Development of Protein-Protein Interaction Modulators by Virtual Screening Book
2015
Authors:  Ma D.-L.;  Liu L.-J.;  Lin S.;  Wang M.;  Chan D.S.-H.;  Leung C.-H.
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Computer-aided drug discovery  Drug development  Molecular docking  Protein-protein interactions  Virtual screening  
Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening Journal article
Methods, 2015,Volume: 71,Issue: C,Page: 38-43
Authors:  Leung K.-H.;  Liu L.-J.;  Lin S.;  Lu L.;  Zhong H.-J.;  Susanti D.;  Rao W.;  Wang M.;  Che W.I.;  Chan D.S.H.;  Leung C.-H.;  Chan P.W.H.;  Ma D.-L.
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Pharmacophore  Protein-protein interaction  STAT3  Virtual screening  
In silico identification of natural product inhibitors of JAK2 Journal article
Methods, 2015,Volume: 71,Issue: C,Page: 21-25
Authors:  Zhong H.-J.;  Lin S.;  Tam I.L.;  Lu L.;  Chan D.S.-H.;  Ma D.-L.;  Leung C.-H.
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6-Chloroemodic acid  Emodic acid  JAK2  Natural product  Virtual screening  
Pharmacophore modeling for the identification of small-molecule inhibitors of TACE Journal article
Methods, 2015,Volume: 71,Issue: C,Page: 92-97
Authors:  Liu L.-J.;  Leung K.-H.;  Lin S.;  Chan D.S.-H.;  Susanti D.;  Rao W.;  Chan P.W.H.;  Ma D.-L.;  Leung C.-H.
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Inhibitor  Pharmacophore  TACE  Tumor necrosis factor  Virtual screening  
Structure-based repurposing of FDA-approved drugs as inhibitors of NEDD8-activating enzyme Journal article
Biochimie, 2014,Volume: 102,Issue: 1,Page: 211-215
Authors:  Zhong H.-J.;  Liu L.-J.;  Chan D.S.-H.;  Wang H.-M.;  Chan P.W.H.;  Ma D.-L.;  Leung C.-H.
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Inhibitor  NEDD8-activating enzyme  Repurposing  Structure-based  Virtual screening  
Structure-based repurposing of FDA-approved drugs as TNF-α inhibitors Journal article
ChemMedChem, 2011,Volume: 6,Issue: 5,Page: 765-768
Authors:  Leung C.-H.;  Chan D.S.-H.;  Kwan M.H.-T.;  Cheng Z.;  Wong C.-Y.;  Zhu G.-Y.;  Fong W.-F.;  Ma D.-L.
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Approved drugs  Drug discovery  Inhibitors  Tumor necrosis factor  Virtual screening