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Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease Journal article
ORPHANET JOURNAL OF RARE DISEASES, 2018,Volume: 13
Authors:  Vu, Mylinh;  Li, Rong;  Baskfield, Amanda;  Lu, Billy;  Farkhondeh, Atena;  Gorshkov, Kirill;  Motabar, Omid;  Beers, Jeanette;  Chen, Guokai;  Zou, Jizhong;  Espejo-Mojica, Angela J.;  Rodriguez-Lopez, Alexander;  Almeciga-Diaz, Carlos J.;  Barrera, Luis A.;  Jiang, Xuntian;  Ory, Daniel S.;  Marugan, Juan J.;  Zheng, Wei
Favorite  |  View/Download:15/0  |  Submit date:2018/10/30
Tay-Sachs disease  Induced pluripotent stem cells  Neural stem cells  Cyclodextrin  HP beta CD  delta-tocopherol  Enzyme replacement therapy  Hexosaminidase A  GM2 gangliosidosis  High throughput screening  Drug discovery  
Computer-Aided Formulation Design for a Highly Soluble Lutein-Cyclodextrin Multiple-Component Delivery System Journal article
MOLECULAR PHARMACEUTICS, 2018,Volume: 15,Issue: 4,Page: 1664-1673
Authors:  Zhao, Qianqian;  Miriyala, Nikhila;  Su, Yan;  Chen, Weijie;  Gao, Xuejiao;  Shao, Ling;  Yan, Ru;  Li, Haifeng;  Yao, Xiaojun;  Cao, Dongsheng;  Wang, Yitao;  Ouyang, Defang
View  |  Adobe PDF(4697Kb)  |  Favorite  |  View/Download:182/21  |  Submit date:2018/10/30
Lutein  Cyclodextrin  Multiple-component System  Molecular Dynamics Simulation  Bioavailability  Computer-aided Formulation Design  
Research Advances in Molecular Modeling in Cyclodextrins Journal article
CURRENT PHARMACEUTICAL DESIGN, 2017,Volume: 23,Issue: 3,Page: 522-531
Authors:  Zhao, Qianqian;  Zhang, Weixiang;  Wang, Runmiao;  Wang, Yitao;  Ouyang, Defang
Favorite  |  View/Download:14/0  |  Submit date:2018/10/30
Cyclodextrin  Molecular Modeling  Knowledge Map  Molecular Dynamics  Inclusion Complexes  
Induced pluripotent stem cells for disease modeling and evaluation of therapeutics for niemann-pick disease type A Journal article
Stem Cells Translational Medicine, 2016,Volume: 5,Issue: 12,Page: 1644-1655
Authors:  Long Y.;  Xu M.;  Li R.;  Dai S.;  Beers J.;  Chen G.;  Soheilian F.;  Baxa U.;  Wang M.;  Marugan J.J.;  Muro S.;  Li Z.;  Brady R.;  Zheng W.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/21
Acid Sphingomyelinase  Cyclodextrin  Differentiated Neural Stem Cells  Induced Pluripotent Stem Cells  Niemann-pick Disease Type a  Α-tocopherol  Δ-tocopherol  
Pluronic F127-modified liposome-containing tacrolimus-cyclodextrin inclusion complexes: Improved solubility, cellular uptake and intestinal penetration Journal article
Journal of Pharmacy and Pharmacology, 2013,Volume: 65,Issue: 8,Page: 1107-1117
Authors:  Zhu Q.;  Guo T.;  Xia D.;  Li X.;  Zhu C.;  Li H.;  Ouyang D.;  Zhang J.;  Gan Y.
Favorite  |  View/Download:1/0  |  Submit date:2019/01/15
Cellular Uptake  Cyclodextrin Inclusion Complex  Molecular Modelling  Pluronic F127-modified Liposomes  Solubility  Tacrolimus  
Molecular modeling-based inclusion mechanism and stability studies of doxycycline and hydroxypropyl-β-cyclodextrin complex for ophthalmic delivery Journal article
AAPS PharmSciTech, 2013,Volume: 14,Issue: 1,Page: 10
Authors:  Zhang H.;  Chen M.;  He Z.;  Wang Z.;  Zhang M.;  He Z.;  Wan Q.;  Liang D.;  Repka M.A.;  Wu C.
Favorite  |  View/Download:5/0  |  Submit date:2018/10/30
doxycycline  hydroxypropyl-β-cyclodextrin  inclusion mechanism  molecular modeling  stability