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Increased expression of IRE1α associates with the resistant mechanism of osimertinib (AZD9291)-resistant non-small cell lung cancer HCC827/OSIR cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 4,Page: 550-555
Authors:  Tang Z.-H.;  Su M.-X.;  Guo X.;  Jiang X.-M.;  Jia L.;  Chen X.;  Lu J.-J.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/28
Azd9291  Egfr  Ire1α  Lune Cancer  Nsclc  Osimertinib  
2-methoxy-6-acetyl-7-methyljuglone (MAM) induces iNOS/NO-mediated DNA damage response through activation of MAPKs pathways Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 6,Page: 903-913
Authors:  Niu Y.;  Yuan R.;  Gao H.;  Lu J.-J.;  Kong Q.;  Chen X.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/28
Atm/chk2  Dna Damage  Inos/no  L-arginine  Mam  Mapks  
Cryptotanshinone induces pro-death autophagy through JNK signaling mediated by reactive oxygen species generation in lung cancer cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2016,Volume: 16,Issue: 5,Page: 593
Authors:  Hao W.;  Zhang X.;  Zhao W.;  Zhu H.;  Liu Z.-Y.;  Lu J.;  Chen X.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/30
Autophagy  Cancer  Cryptotanshinone  Jnk  Reactive Oxygen Species  
Anti-proliferative activities of terpenoids isolated from alisma orientalis and their structure-activity relationships Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2015,Volume: 15,Issue: 2,Page: 228-235
Authors:  Xu W.;  Li T.;  Qiu J.-F.;  Wu S.-S.;  Huang M.-Q.;  Lin L.-G.;  Zhang Q.-W.;  Chen X.-P.;  Lu J.-J.
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Alisma Orientalis  Alisol b  Anti-proliferative  Protostane  Structure-activity Relationships  Triterpenoid  
Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in leukemia K562 cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2014,Volume: 14,Issue: 8,Page: 1146-1153
Authors:  Guo J.;  Zhao W.;  Hao W.;  Ren G.;  Lu J.;  Chen X.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/28
Apoptosis  Cancer  Cucurbitacin b  Dna Damage  G2/m Arrest  Ros