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Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells Journal article
FOOD AND CHEMICAL TOXICOLOGY, 2019,Volume: 131
Authors:  Mu-Yang Huang;  Xiao-Ming Jiang;  Yu-Lian Xu;  Luo-Wei Yuan;  Yu-Chi Chen;  Guozhen Cui;  Run-Yue Huang;  Bo Liu;  Yitao Wang;  Xiuping Chen;  Jin-Jian Lu
Favorite  |  View/Download：2/0  |  Submit date：2019/11/22
Programmed Death Ligand-1  Platycodin d  Extracellular Release  Natural Products  Cancer  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download：245/23  |  Submit date：2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Recent progress in doxorubicin-induced cardiotoxicity and protective potential of natural products Journal article
PHYTOMEDICINE, 2018,Volume: 40,Page: 125-139
Authors:  Yu, Jie;  Wang, Changxi;  Kong, Qi;  Wu, Xiaxia;  Lu, Jin-Jian;  Chen, Xiuping
Favorite  |  View/Download：13/0  |  Submit date：2018/10/30
Doxorubicin  Cardiotoxicity  Natural Products  
Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer Journal article
CANCER LETTERS, 2018,Volume: 412,Page: 1-9
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Guo, Xia;  Dai, Xiao-Yang;  Lu, Jia-Hong;  Chen, Xiuping;  Zhu, Hong;  Lu, Jin-Jian
Favorite  |  View/Download：12/0  |  Submit date：2018/10/30
Cepharanthine  Autophagy  Lysosome  Dacomitinib  Nsclc  
Cucurbitacin B suppresses metastasis mediated by reactive oxygen species (ROS) via focal adhesion kinase (FAK) in breast cancer MDA-MB-231 cells Journal article
CHINESE JOURNAL OF NATURAL MEDICINES, 2018,Volume: 16,Issue: 1,Page: 10-19
Authors:  Luo Wei-Wei;  Zhao Wen-Wen;  Lu Jin-Jian;  Wang Yi-Tao;  Chen Xiu-Ping
Favorite  |  View/Download：19/0  |  Submit date：2018/10/30
Cucurbitacin b  Metastasis  Ros  Fak  Breast Cancer  
Baicalein protects tert-butyl hydroperoxide-induced hepatotoxicity dependent of reactive oxygen species removal Journal article
MOLECULAR MEDICINE REPORTS, 2017,Volume: 16,Issue: 6,Page: 8392-8398
Authors:  Wang, Ya-Fang;  Tang, Zheng-Hai;  Li, Ting;  Xu, Xiao-Huang;  Chen, Xiuping;  Wang, Ying;  Wang, Yi-Tao;  Lu, Jin-Jian
Favorite  |  View/Download：16/0  |  Submit date：2018/10/30
Baicalein  Liver Protection  Reactive Oxygen Species  Apoptosis  
Osimertinib (AZD9291) decreases programmed death ligand-1 in EGFR-mutated non-small cell lung cancer cells Journal article
ACTA PHARMACOLOGICA SINICA, 2017,Volume: 38,Issue: 11,Page: 1512-1520
Authors:  Jiang, Xiao-Ming;  Xu, Yu-Lian;  Huang, Mu-Yang;  Zhang, Le-Le;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite  |  View/Download：15/0  |  Submit date：2018/10/30
Non-small Cell Lung Cancer  Egfr  Osimertinib  Pd-l1  Ubiquitin-proteasome System  Mg-132  Bortezomib  Gsk3 Beta  Licl  
Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 44,Page: 77673-77684
Authors:  Wu, Ming-Yue;  Wang, Sheng-Fang;  Cai, Cui-Zan;  Tan, Jie-Qiong;  Li, Min;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Wang, Yi-Tao;  Zheng, Wei;  Lu, Jia-Hong
Favorite  |  View/Download：14/0  |  Submit date：2018/10/30
Dauricine  Daurisoline  Autophagy Blocker  Cancer Cells  Cell Toxicity  
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Xu, Xiao-Huang;  Liu, Qian-Yu;  Li, Ting;  Liu, Jian-Lin;  Chen, Xin;  Huang, Li;  Qiang, Wen-An;  Chen, Xiuping;  Wang, Yitao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(5330Kb)  |  Favorite  |  View/Download：128/10  |  Submit date：2018/10/30
Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 330,Page: 65-73
Authors:  Li, Ting;  Chen, Xin;  Dai, Xiao-Yang;  Wei, Bin;  Weng, Qin-Jie;  Chen, Xiuping;  Ouyang, De-Fang;  Yan, Ru;  Huang, Zhang-Jian;  Jiang, Hu-Lin;  Zhu, Hong;  Lu, Jin-Jian
Favorite  |  View/Download：7/0  |  Submit date：2018/10/30
Everolimus  Platycodin d  Hsp90  Cdc37  Egfr  Igf1r