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A rare variant in MLKL confers susceptibility to ApoE ɛ4-negative Alzheimer's disease in Hong Kong Chinese population Journal article
Neurobiology of Aging, 2018,Volume: 68,Page: 160.e1-160.e7
Authors:  Wang B.;  Bao S.;  Zhang Z.;  Zhou X.;  Wang J.;  Fan Y.;  Zhang Y.;  Li Y.;  Chen L.;  Jia Y.;  Li J.;  Li M.;  Zheng W.;  Mu N.;  Wang L.;  Yu Z.;  Wong D.S.M.;  Zhang Y.;  Kwan J.;  Ka-Fung Mak H.;  Ambalavanan A.;  Zhou S.;  Cai W.;  Zheng J.;  Huang S.;  Rouleau G.A.;  Yang W.;  Rogaeva E.;  Ma X.;  St George-Hyslop P.;  Chu L.W.;  Song Y.-Q.
Favorite  |  View/Download:9/0  |  Submit date:2018/12/21
Apoe Ɛ4-negative  Late-onset Alzheimer's Disease  Mlkl  Whole Exome Sequencing  
Signalling pathways regulating galactosaminoglycan synthesis and structure in vascular smooth muscle: Implications for lipoprotein binding and atherosclerosis Journal article
PHARMACOLOGY & THERAPEUTICS, 2018,Volume: 187,Page: 88-97
Authors:  Afroz, Rizwana;  Cao, Yingnan;  Rostam, Muhamad Ashraf;  Ta, Hang;  Xu, Suowen;  Zheng, Wenhua;  Osman, Narin;  Kamato, Danielle;  Little, Peter J.
Favorite  |  View/Download:19/0  |  Submit date:2018/10/30
Atherosclerosis  Proteoglycans  Galactosaminoglycans  Signalling Pathways  
IGF-1-Mediated Survival from Induced Death of Human Primary Cultured Retinal Pigment Epithelial Cells Is Mediated by an Akt-Dependent Signaling Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 3,Page: 1915-1927
Authors:  Zheng, Wenhua;  Meng, Qian;  Wang, Haitao;  Yan, Fengxia;  Little, Peter J.;  Deng, Xinguo;  Lin, Shaofen
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Retinopathy  Serum Deprivation  Cell Signaling  Apoptosis  Growth Factors  
Artemisinin Protects Retinal Neuronal Cells against Oxidative Stress and Restores Rat Retinal Physiological Function from Light Exposed Damage Journal article
ACS Chemical Neuroscience, 2017,Volume: 8,Issue: 8,Page: 1713-1723
Authors:  Yan F.;  Wang H.;  Gao Y.;  Xu J.;  Zheng W.
Favorite  |  View/Download:7/0  |  Submit date:2018/12/21
AMD  artemisin  ERK1/2  H2O2  p38  ROS  
Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway Journal article
Redox Biology, 2017,Volume: 12,Page: 625-633
Authors:  Zeng Z.;  Xu J.;  Zheng W.
Favorite  |  View/Download:5/0  |  Submit date:2018/12/21
Alzheimer's Disease  Artemisinin  Aβ25–35  Erk1/2  Pc12 Cells  
The Atypical Antipsychotic Agent, Clozapine, Protects Against Corticosterone-Induced Death of PC12 Cells by Regulating the Akt/FoxO3a Signaling Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 54,Issue: 5,Page: 3395-3406
Authors:  Zeng, Zhiwen;  Wang, Xue;  Bhardwaj, Sanjeev K.;  Zhou, Xuanhe;  Little, Peter J.;  Quirion, Remi;  Srivastava, Lalit K.;  Zheng, Wenhua
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Schizophrenia  Clozapine  Corticosterone  Pi3k/akt/foxo3a  Neuroprotection  
Ga-q proteins: molecular pharmacology and therapeutic potential Journal article
CELLULAR AND MOLECULAR LIFE SCIENCES, 2017,Volume: 74,Issue: 8,Page: 1379-1390
Authors:  Kamato, Danielle;  Mitra, Partha;  Davis, Felicity;  Osman, Narin;  Chaplin, Rebecca;  Cabot, Peter J.;  Afroz, Rizwana;  Thomas, Walter;  Zheng, Wenhua;  Kaur, Harveen;  Brimble, Margaret;  Little, Peter J.
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
g Proteins  Isoforms  g Protein-coupled Receptors  Gpcrs  Par-1  Hyperelongation  Atherosclerosis  g Alpha q  
Artemisinin conferred ERK mediated neuroprotection to PC12 cells and cortical neurons exposed to sodium nitroprusside-induced oxidative insult Journal article
Free Radical Biology and Medicine, 2016,Volume: 97,Page: 158-167
Authors:  Zheng W.;  Chong C.-M.;  Wang H.;  Zhou X.;  Zhang L.;  Wang R.;  Meng Q.;  Lazarovici P.;  Fang J.
Favorite  |  View/Download:9/0  |  Submit date:2018/12/21
Artemisinin  Erk1/2  Neuroprotection  Pc12 Cells  Sodium Nitroprusside  
The role of specific Smad linker region phosphorylation in TGF-beta mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle Journal article
CELLULAR SIGNALLING, 2016,Volume: 28,Issue: 8,Page: 956-966
Authors:  Muhamad A. Rostam;  Danielle Kamato;  Terence J. Piva;  Wenhua Zheng;  Peter J. Little;  Narin Osman
Favorite  |  View/Download:7/0  |  Submit date:2020/06/11
Transforming Growth Factor-beta  Glycosaminoglycan  Atherosclerosis  Vascular Smooth Muscle  Signalling  Smad  
Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling Journal article
British Journal of Pharmacology, 2016,Volume: 173,Issue: 20,Page: 2992-3000
Authors:  Little P.J.;  Hollenberg M.D.;  Kamato D.;  Thomas W.;  Chen J.;  Wang T.;  Zheng W.;  Osman N.
Favorite  |  View/Download:19/0  |  Submit date:2018/12/21