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Pluronic P85/F68 Micelles of Baicalein Could Interfere with Mitochondria to Overcome MRP2-Mediated Efflux and Offer Improved Anti-Parkinsonian Activity Journal article
Molecular Pharmaceutics, 2017,Volume: 14,Issue: 10,Page: 3331-3342
Authors:  Chen T.;  Li Y.;  Li C.;  Yi X.;  Wang R.;  Lee S.M.-Y.;  Zheng Y.
Favorite  |  View/Download:8/0  |  Submit date:2018/11/06
Baicalein  Fluorescence Resonance Energy Transfer (Fret)  Micelles  Mitochondria  Multidrug Resistance-associated Protein 2 (Mrp2)  Neuroprotective Effect  
Multiple cellular targets of the neuroprotectant BHDPC in autoimmune mediated CNS demyelination Conference paper
Proceedings of 13th European Meeting on Glial Cells in Health and Disease, Edinburgh, SCOTLAND, JUL 08-11, 2017
Authors:  Zhao, C.;  Ma, D.;  Yonetani, M.;  Chong, C. -M.;  Li, C. -W.;  Peruzzotti-Jametti, L.;  Balzarotti, B.;  Wang, L.;  Wu, Z.;  Zheng, Y.;  Pluchino, S.;  Franklin, R. J. M.;  Lee, S. M.
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Oral delivery of a nanocrystal formulation of schisantherin a with improved bioavailability and brain delivery for the treatment of Parkinson's disease Journal article
Molecular Pharmaceutics, 2016,Volume: 13,Issue: 11,Page: 3864-3875
Authors:  Chen T.;  Li C.;  Li Y.;  Yi X.;  Lee S.M.-Y.;  Zheng Y.
Favorite  |  View/Download:5/0  |  Submit date:2018/11/06
Brain Delivery  Dissolution  Nanocrystals  Oral Bioavailability  Parkinson's Disease (Pd)  
Formulation of 20(S)-protopanaxadiol nanocrystals to improve oral bioavailability and brain delivery Journal article
International Journal of Pharmaceutics, 2016,Volume: 497,Issue: 1-2,Page: 239-247
Authors:  Chen C.;  Wang L.;  Cao F.;  Miao X.;  Chen T.;  Chang Q.;  Zheng Y.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/28
20(s)-protopanaxadiol  Bioavailability  Brain Delivery  D-α-tocopheryl Polyethylene Glycol 1000 Succinate  Nanocrystals  
Development and characterisation of ursolic acid nanocrystals without stabiliser having improved dissolution rate and in vitro anticancer activity Journal article
AAPS PharmSciTech, 2014,Volume: 15,Issue: 1,Page: 11
Authors:  Song Ju.;  Wang Y.;  Song Y.;  Chan H.;  Bi C.;  Yang X.;  Yan R.;  Wang Y.;  Zheng Y.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/30
Anticancer  Dissolution  Mcf-7  Nanocrystals  Ursolic Acid  
Blends of hydrophobic and swelling agents in the swelling layer in the preparation of delayed-release pellets of a hydrophilic drug with low MW: Physicochemical characterizations and in-vivo evaluations Journal article
Asian Journal of Pharmaceutical Sciences, 2014,Volume: 9,Issue: 4,Page: 199
Authors:  You C.;  Liang X.;  Sun J.;  Sun L.;  Wang Y.;  Fan T.;  Zheng Y.
Favorite  |  View/Download:1/0  |  Submit date:2018/10/31
Cross-linked Sodium Carboxymethyl Cellulose (Cc-na)  Danshensu  Delayed-release Pellets  Fluidised Bed  Surelease®  Swelling Agent  
Curcumin-loaded solid lipid nanoparticles have prolonged in vitro antitumour activity, cellular uptake and improved in vivo bioavailability Journal article
Colloids and Surfaces B: Biointerfaces, 2013,Volume: 111,Page: 367
Authors:  Sun J.;  Bi C.;  Chan H.M.;  Sun S.;  Zhang Q.;  Zheng Y.
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Bioavailability  Cellular Uptake  Curcumin  Sefsol-218®  Solid Lipid Nanoparticles (Slns)  Stability  
In vitro and in vivo anticancer activity of a novel puerarin nanosuspension against colon cancer, with high efficacy and low toxicity Journal article
International Journal of Pharmaceutics, 2013,Volume: 441,Issue: 2018-01-02,Page: 728
Authors:  Wang Y.;  Ma Y.;  Zheng Y.;  Song J.;  Yang X.;  Bi C.;  Zhang D.;  Zhang Q.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/30
Apoptosis  Ht-29 Cells  In Vivo  Nanosuspensions  Puerarin  
Self-nanoemulsifying drug delivery system (SNEDDS) for oral delivery of Zedoary essential oil: Formulation and bioavailability studies Journal article
International Journal of Pharmaceutics, 2010,Volume: 383,Issue: 1-2,Page: 170
Authors:  Zhao Y.;  Wang C.;  Chow A.H.L.;  Ren K.;  Gong T.;  Zhang Z.;  Zheng Y.
Favorite  |  View/Download:5/0  |  Submit date:2018/10/30
Bioavailability  Essential Oil  Formulation  Pseudo-ternary Phase Diagram  Self-nanoemulsifying  Zedoary Turmeric Oil