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A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 820,Page: 86-96
Authors:  Tang, Fan;  Zhou, Xinhua;  Wang, Liang;  Shan, Luchen;  Li, Chuwen;  Zhou, Hefeng;  Lee, Simon Ming-Yuen;  Hoi, Maggie Pui-Man
Favorite  |  View/Download:16/0  |  Submit date:2018/10/30
Cardioprotection  Anti-oxidative stress  Anti-apoptosis  Autophagy regulation  Zebrafish cardiotoxicity  H9c2 cardiomyocytes  
The high-quality genome of Brassica napus cultivar ‘ZS11’ reveals the introgression history in semi-winter morphotype Journal article
Plant Journal, 2017,Volume: 92,Issue: 3,Page: 452-468
Authors:  Sun F.;  Fan G.;  Hu Q.;  Zhou Y.;  Guan M.;  Tong C.;  Li J.;  Du D.;  Qi C.;  Jiang L.;  Liu W.;  Huang S.;  Chen W.;  Yu J.;  Mei D.;  Meng J.;  Zeng P.;  Shi J.;  Liu K.;  Wang X.;  Wang X.;  Long Y.;  Liang X.;  Hu Z.;  Huang G.;  Dong C.;  Zhang H.;  Li J.;  Zhang Y.;  Li L.;  Shi C.;  Wang J.;  Lee S.M.-Y.;  Guan C.;  Xu X.;  Liu S.;  Liu X.;  Chalhoub B.;  Hua W.;  Wang H.
Favorite  |  View/Download:11/0  |  Submit date:2018/11/06
allotetraploid  Brassica napus  genome  homoeolog  introgression  next-generation sequencing technologies  polyploid  subgenome  ZS11  
An andrographolide derivative AGP-26b exibitiing anti-angiogenic activity in HUVECs and zebrafish via blocking the VEGFA/VEGFR2 signaling pathway Journal article
MOLECULAR BIOSYSTEMS, 2017,Volume: 13,Issue: 3,Page: 525-536
Authors:  Huang, Bin;  Peng, Yuran;  Li, Jingjing;  Li, Shang;  Sun, Yicheng;  Wang, Decai;  Yang, Binrui;  Chan, Judy Yuet-Wa;  Yu, Huidong;  Leung, George Pak-Heng;  Hoi, Maggie Pui-Man;  Zhou, Guo-Chun;  Lee, Simon Ming-Yuen
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Draft genome of the living fossil Ginkgo biloba Journal article
GigaScience, 2016,Volume: 5,Issue: 1
Authors:  Guan R.;  Zhao Y.;  Zhang H.;  Fan G.;  Liu X.;  Zhou W.;  Shi C.;  Wang J.;  Liu W.;  Liang X.;  Fu Y.;  Ma K.;  Zhao L.;  Zhang F.;  Lu Z.;  Lee S.M.-Y.;  Xu X.;  Wang J.;  Yang H.;  Fu C.;  Ge S.;  Chen W.
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Evolution of LTR-RTs  Ginkgo genome  Gymnosperm evolution  Plant defense mechanism  Tandem gene duplication  Whole genome duplication  
Synergistic effect of fenretinide and curcumin for treatment of non-small cell lung cancer Journal article
Cancer Biology and Therapy, 2016,Volume: 17,Issue: 10,Page: 1022-1029
Authors:  Chen H.;  Chen L.;  Wang L.;  Zhou X.;  Chan J.Y.-W.;  Li J.;  Cui G.;  Lee S.M.-Y.
Favorite  |  View/Download:5/0  |  Submit date:2018/11/06
Curcumin  fenretinide  GRP78  non-small cell lung cancer  
A New Danshensu Derivative Protects Against 6-Hydroxydopamine-Induced Neurotoxicity in Vitro and in Vivo Journal article
American Journal of Chinese Medicine, 2016,Volume: 44,Issue: 7,Page: 1349-1361
Authors:  Cui G.;  Shan L.;  Chen Y.;  Zhou H.;  Wang Y.;  Lee S.M.-Y.
Favorite  |  View/Download:2/0  |  Submit date:2018/11/06
Anti-Inflammation  Anti-Oxidation  Danshensu Derivative  Neuroprotection  
A novel agent enhances the chemotherapeutic efficacy of doxorubicin in MCF-7 breast cancer cells Journal article
Frontiers in Pharmacology, 2016,Volume: 7,Issue: AUG
Authors:  Wang L.;  Chan J.Y.;  Zhou X.;  Cui G.;  Yan Z.;  Wang L.;  Yan R.;  Di L.;  Wang Y.;  Hoi M.P.;  Shan L.;  Lee S.M.
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Breast Cancer  Danshensu  Doxorubicin  Glycolysis  Grp78 Protein  Tetramethylpyrazine  
Anti-angiogenic activity of a new andrographolide derivative in zebrafish and HUVECs Journal article
European Journal of Pharmacology, 2016,Volume: 789,Page: 344-353
Authors:  Li J.;  Peng Y.;  Li S.;  Sun Y.;  Chan J.Y.-W.;  Cui G.;  Wang D.;  Zhou G.-C.;  Lee S.M.-Y.
Favorite  |  View/Download:2/0  |  Submit date:2018/11/06
Andrographolide  Angiogenesis  Zebrafish  
Amelioration of acute myocardial infarction by saponins from flower buds of Panax notoginseng via pro-angiogenesis and anti-apoptosis Journal article
Journal of Ethnopharmacology, 2016,Volume: 181,Page: 50
Authors:  Yang B.-R.;  Cheung K.-K.;  Zhou X.;  Xie R.-F.;  Cheng P.-P.;  Wu S.;  Zhou Z.-Y.;  Tang J.Y.;  Hoi P.M.;  Wang Y.-H.;  Lee S.M.-Y.
Favorite  |  View/Download:5/0  |  Submit date:2018/10/30
Angiogenesis  Apoptosis  Myocardial Infarction  Panax Notoginseng Flower  Saponin  
Neuroprotective effects of the andrographolide analogue AL-1 in the MPP+/MPTP-induced Parkinson's disease model in vitro and in mice Journal article
Pharmacology Biochemistry and Behavior, 2014,Volume: 122,Page: 191-202
Authors:  Zhang Z.;  Lai D.;  Wang L.;  Yu P.;  Zhu L.;  Guo B.;  Xu L.;  Zhou L.;  Sun Y.;  Lee S.M.Y.;  Wang Y.
Favorite  |  View/Download:9/0  |  Submit date:2018/11/06
Andrographolide-lipoic Acid Conjugate  Neuroprotection  Nf-κb P65  Parkinson's Disease