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Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2009,Volume: 19,Issue: 17,Page: 5229-5232
Authors:  Jin H.;  Cianchetta G.;  Devasagayaraj A.;  Gu K.;  Marinelli B.;  Samala L.;  Scott S.;  Stouch T.;  Tunoori A.;  Wang Y.;  Zang Y.;  Zhang C.;  David Kimball S.;  Main A.J.;  Ding Z.-M.;  Sun W.;  Yang Q.;  Yu X.-Q.;  Powell D.R.;  Wilson A.;  Liu Q.;  Shi Z.-C.
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5-HT  Gastrointestinal disorders  TPH1  Tryptophan hydroxylase  
Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 19,Page: 5102-5106
Authors:  Smith II L.;  Wong W.C.;  Kiselyov A.S.;  Burdzovic-Wizemann S.;  Mao Y.;  Xu Y.;  Duncton M.A.J.;  Kim K.;  Piatnitski E.L.;  Doody J.F.;  Wang Y.;  Rosler R.L.;  Milligan D.;  Columbus J.;  Balagtas C.;  Lee S.P.;  Konovalov A.;  Hadari Y.R.
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Diazepine  Epidermal growth factor receptor  Kinase inhibitor  Oxazepine  Thiazepine  
Tricyclic azepine derivatives: Pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 6,Page: 1643-1646
Authors:  Smith II L.;  Piatnitski E.L.;  Kiselyov A.S.;  Ouyang X.;  Chen X.;  Burdzovic-Wizemann S.;  Xu Y.;  Wang Y.;  Rosler R.L.;  Patel S.N.;  Chiang H.-H.;  Milligan D.L.;  Columbus J.;  Wong W.C.;  Doody J.F.;  Hadari Y.R.
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Benzoxazepine  Epidermal growth factor receptor  Kinase inhibitor  Kinase selectivity  
Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 5,Page: 1191-1196
Authors:  Ouyang X.;  Piatnitski E.L.;  Pattaropong V.;  Chen X.;  He H.-Y.;  Kiselyov A.S.;  Velankar A.;  Kawakami J.;  Labelle M.;  Smith II L.;  Lohman J.;  Lee S.P.;  Malikzay A.;  Fleming J.;  Gerlak J.;  Wang Y.;  Rosler R.L.;  Zhou K.;  Mitelman S.;  Camara M.;  Surguladze D.;  Doody J.F.;  Tuma M.C.
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1,3,4-Oxadiazole  Antimitotic agent  Multiple-drug resistance  Tubulin polymerization inhibitor  
Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2005,Volume: 15,Issue: 23,Page: 5154-5159
Authors:  Ouyang X.;  Chen X.;  Piatnitski E.L.;  Kiselyov A.S.;  He H.-Y.;  Mao Y.;  Pattaropong V.;  Yu Y.;  Kim K.H.;  Kincaid J.;  Smith II L.;  Wong W.C.;  Lee S.P.;  Milligan D.L.;  Malikzay A.;  Fleming J.;  Gerlak J.;  Deevi D.;  Doody J.F.;  Chiang H.-H.;  Patel S.N.;  Wang Y.;  Rolser R.L.;  Kussie P.;  Labelle M.;  Tuma M.C.
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1,2,4-Triazole  Antimitotic  Tubulin inhibitor  Tubulin polymerization  Tumor vasculature  Vascular disrupting agent