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Ginseng polysaccharides enhanced ginsenoside Rb1 and microbial metabolites exposure through enhancing intestinal absorption and affecting gut microbial metabolism Journal article
JOURNAL OF ETHNOPHARMACOLOGY, 2018,Volume: 216,Page: 47-56
Authors:  Shen, Hong;  Gao, Xue-Jiao;  Li, Ting;  Jing, Wang-Hui;  Han, Bei-Lei;  Jia, Yu-Meng;  Hu, Nan;  Yan, Zhi-Xiang;  Li, Song-Lin;  Yan, Ru
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Development and characterisation of ursolic acid nanocrystals without stabiliser having improved dissolution rate and in vitro anticancer activity Journal article
AAPS PharmSciTech, 2014,Volume: 15,Issue: 1,Page: 11
Authors:  Song Ju.;  Wang Y.;  Song Y.;  Chan H.;  Bi C.;  Yang X.;  Yan R.;  Wang Y.;  Zheng Y.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/30
Anticancer  Dissolution  Mcf-7  Nanocrystals  Ursolic Acid  
Simultaneously enantiospecific determination of (+)-trans-khellactone, (+/-)-praeruptorin A, (+/-)-praeruptorin B, (+)-praeruptorin E, and their metabolites, (+/-)-cis-khellactone, in rat plasma using online solid phase extraction-chiral LC-MS/MS Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2014,Volume: 88,Page: 269
Authors:  Song Y.;  Jing W.;  Yang F.;  Shi Z.;  Yao M.;  Yan R.;  Wang Y.
Favorite  |  View/Download:9/0  |  Submit date:2018/10/31
Chiral Lc-ms/ms  Enantiospecific  Online Spe  Peucedani Radix  Pharmacokinetics  
Metabolic characterization of (±)-praeruptorin A in vitro and in vivo by high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-flight mass spectrometry Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2014,Volume: 90,Page: 98
Authors:  Song Y.-L.;  Jing W.-H.;  Yan R.;  Wang Y.-T.
Favorite  |  View/Download:9/0  |  Submit date:2018/10/31
(±)-Praeruptorin A  In vivo  LightSight™ software  Metabolism  Peucedani Radix  
Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupl Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2013,Volume: 77,Page: 175-188
Authors:  Jing, Wang-Hui;  Song, Yue-Lin;  Yan, Ru;  Wang, Yi-Tao
Favorite  |  View/Download:11/0  |  Submit date:2018/11/01
Angular-type Pyranocoumarins  (+)-praeruptorin a  Uhplc-qt-ms/ms  Human Liver Microsomes  Cyp 3a4  
Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupled with tandem mass spectrometry Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2013,Volume: 77,Page: 175
Authors:  Jing W.-H.;  Song Y.-L.;  Yan R.;  Wang Y.-T.
Favorite  |  View/Download:1/0  |  Submit date:2018/10/31
(+)-praeruptorin a  Angular-type Pyranocoumarins  Cyp 3a4  Human Liver Microsomes  Uhplc-qt-ms/ms  
Extraction of the Main Ingredients from Chuanxiong by CO2 Supercritical Fluid Extraction Journal article
American Journal of Analytical Chemistry, 2012,Volume: 3,Issue: 12A,Page: 905-915
Authors:  Ru Yan;  Song-Lin Li;  Ge Lin
Favorite  |  View/Download:1/0  |  Submit date:2019/01/15
Chuanxiong Rhizoma  Supercritical Fluid Extraction  Selective Enrichment  
Enantioseparation and Absolute Configuration Determination of Angular-Type Pyranocoumarins from Peucedani Radix Using Enzymatic Hydrolysis and Chiral HPLC-MS/MS Analysis Journal article
MOLECULES, 2012,Volume: 17,Issue: 4,Page: 4236-4251
Authors:  Song, YL (Song, Yue-Lin);  Zhang, QW (Zhang, Qing-Wen);  Li, YP (Li, Ya-Ping);  Yan, R (Yan, Ru);  Wang, YT (Wang, Yi-Tao)
View  |  Adobe PDF(384Kb)  |  Favorite  |  View/Download:105/3  |  Submit date:2018/11/01
Stereoselective metabolism of (+/-)-praeruptorin A, a calcium channel blocker from Peucedani Radix, in pooled liver microsomes of rats and humans Journal article
XENOBIOTICA, 2012,Volume: 42,Issue: 3,Page: 221-237
Authors:  Song, YL (Song, Y. L.);  ing, WH (Jing, W. H.);  Zhao, HY (Zhao, H. Y.);  Yan, R (Yan, R.);  Li, PT (Li, P. T.);  Wang, YT (Wang, Y. T.)
Favorite  |  View/Download:10/0  |  Submit date:2018/11/01
Aninitric-oxide Production  Caco-2 Cell Monolayers  Anti-aids Agents  Angelica-furcijuga  In-vitro  Inhibitory-activities  Human Cytochrome-p450  Species-differences  Cancer-cells  Qian-hu  
Pharmacokinetic evidence on the contribution of intestinal bacterial conversion to beneficial effects of Astragaloside IV, a marker compound of Astragali Radix, in traditional oral use of the herb Journal article
Drug Metabolism and Pharmacokinetics, 2012,Volume: 27,Issue: 6,Page: 586
Authors:  Zhou R.-N.;  Song Y.-L.;  Ruan J.-Q.;  Wang Y.-T.;  Yan R.
Favorite  |  View/Download:4/0  |  Submit date:2018/10/30
3-epi-cycloastragenol  Astragali Radix  Astragaloside Iv  Cycloastragenol  Intestinal Bacteria  Metabolism  Oral Pharmacokinetics