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Hydroxyurea Facilitates Manifestation of Disease Relevant Phenotypes in Patients-Derived IPSCs-Based Modeling of Late-Onset Parkinson’s Disease Journal article
AGING AND DISEASE, 2019,Volume: 10,Issue: 5,Page: 1037-1048
Authors:  Yuan Tan;  Minjing Ke;  Zhijian Huang;  Cheong-Meng Chong;  Xiaotong Cen;  Jia-Hong Lu;  Xiaoli Yao;  Dajiang Qin;  Huanxing Su
Favorite  |  View/Download:7/0  |  Submit date:2020/04/08
Disease Phenotypes  Er Stress  Induced Pluripotentstem Cells  Parkinson’s Disease  Hydroxyurea  
Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology Journal article
FRONTIERS IN PHARMACOLOGY, 2019
Authors:  Ning-Ning Yuan;  Cui-Zan Cai;  Ming-Yue Wu;  Qi Zhu;  HuanXing Su;  Min Li;  JiaoYan Ren;  Jie-Qiong Tan;  Jia-Hong Lu
Favorite  |  View/Download:18/0  |  Submit date:2020/04/14
Canthin-6-one  Parkinson’s Disease  Alpha-synuclein  Ubiquitin-proteasome-system  Crispr/cas9  Rpn2/psmd1  Pka  
Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling Journal article
CELL DEATH & DISEASE, 2018,Volume: 9,Page: 1-13
Authors:  Cheong-Meng Chong;  Minjing Ke;  Yuan Tan;  Zhijian Huang;  Ke Zhang;  Nana Ai;  Wei Ge;  Dajiang Qin;  Jia-Hong Lu;  Huanxing Su
Favorite  |  View/Download:33/0  |  Submit date:2018/10/30
Corni Fructus: a review of chemical constituents and pharmacological activities Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Dong, Yu;  Feng, Zhe-Ling;  Chen, Hu-Biao;  Wang, Fu-Sheng;  Jia-Hong Lu
Favorite  |  View/Download:25/0  |  Submit date:2018/10/30
Cornus Officinalis Sieb. Et Zucc.  Corni Fructus  Shan Zhu Yu  Phytochemistry  Pharmacological Activity  
Selective autophagy: The new player in the fight against neurodegenerative diseases? Journal article
BRAIN RESEARCH BULLETIN, 2018,Volume: 137,Page: 79-90
Authors:  Wu, Ming-Yue;  Song, Ju-Xian;  Wang, Sheng-Fang;  Cai, Cui-Zan;  Li, Min;  Lu, Jia-Hong
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Selective Autophagy  Neurodegenerative Diesease  Aggrephagy  Chaperone-mediated Autophagy  Mitophagy  
Chemical characterization and immunomodulatory activity of acetylated polysaccharides from Dendrobium devonianum Journal article
CARBOHYDRATE POLYMERS, 2018,Volume: 180,Page: 238-245
Authors:  Deng, Yong;  Li, Min;  Chen, Ling-Xiao;  Chen, Xian-Qiang;  Lu, Jia-Hong;  Zhao, Jing;  Li, Shao-Ping
Favorite  |  View/Download:31/0  |  Submit date:2018/10/30
Dendrobium Devonianum  Chain Conformation  Saccharide Mapping  Immunomodulatory Activity  
Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer Journal article
CANCER LETTERS, 2018,Volume: 412,Page: 1-9
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Guo, Xia;  Dai, Xiao-Yang;  Lu, Jia-Hong;  Chen, Xiuping;  Zhu, Hong;  Lu, Jin-Jian
Favorite  |  View/Download:20/0  |  Submit date:2018/10/30
Cepharanthine  Autophagy  Lysosome  Dacomitinib  Nsclc  
Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 44,Page: 77673-77684
Authors:  Wu, Ming-Yue;  Wang, Sheng-Fang;  Cai, Cui-Zan;  Tan, Jie-Qiong;  Li, Min;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Wang, Yi-Tao;  Zheng, Wei;  Lu, Jia-Hong
Favorite  |  View/Download:20/0  |  Submit date:2018/10/30
Dauricine  Daurisoline  Autophagy Blocker  Cancer Cells  Cell Toxicity  
Baicalein prevents 6-OHDA/ascorbic acid-induced calcium-dependent dopaminergic neuronal cell death Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Wang, Sheng-Fang;  Liu, Liang-Feng;  Wu, Ming-Yue;  Cai, Cui-Zan;  Su, Huanxing;  Tan, Jieqiong;  Lu, Jia-Hong;  Li, Min
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells Journal article
REDOX BIOLOGY, 2017,Volume: 12,Page: 367-376
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Wang, Zhao-Yu;  Lu, Jia-Hong;  Liu, Bo;  Chen, Xiuping;  Lu, Jin-Jian
Favorite  |  View/Download:16/0  |  Submit date:2018/10/30
Chelerythrine  Autophagy  Apoptosis  Ros  Nsclc