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Fighting Liver Fibrosis with Naturally Occurring Antioxidants Journal article
PLANTA MEDICA, 2018,Volume: 84,Issue: 18,Page: 1318-1333
Authors:  Lin, Ligen;  Zhou, Fayang;  Shen, Shengnan;  Zhang, Tian
Favorite  |  View/Download:3/0  |  Submit date:2019/01/17
liver fibrosis  antioxidants  oxidative stress  reactive oxygen species  hepatic stellate cells  natural products  
Water soluble fraction from ethanolic extract of Clausena lansium seeds alleviates obesity and insulin resistance, and changes the composition of gut microbiota in high-fat diet-fed mice Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 47,Page: 192-199
Authors:  Shen, Shengnan;  Liao, Qiwen;  Huang, Li;  Li, Dan;  Zhang, Qingwen;  Wang, Yitao;  Lee, Simon Ming-Yuen;  Lin, Ligen
View  |  Adobe PDF(1563Kb)  |  Favorite  |  View/Download:162/22  |  Submit date:2018/10/30
Clausena Lansium  Fat Mass Gain  Insulin Sensitivity  Gut Microbiota  Wampee  
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
View  |  Adobe PDF(1614Kb)  |  Favorite  |  View/Download:118/11  |  Submit date:2018/10/30
Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
1,3,6,7-Tetrahydroxy-8-prenylxanthone ameliorates inflammatory responses resulting from the paracrine interaction of adipocytes and macrophages Journal article
BRITISH JOURNAL OF PHARMACOLOGY, 2018,Volume: 175,Issue: 10,Page: 1590-1606
Authors:  Li, Dan;  Liu, Qianyu;  Sun, Wen;  Chen, Xiuping;  Wang, Ying;  Sun, Yuxiang;  Lin, Ligen
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Skeletal muscle overexpression of short isoform Sirt3 altered mitochondrial cardiolipin content and fatty acid composition Journal article
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, 2018,Volume: 50,Issue: 2,Page: 131-142
Authors:  Chabi, Beatrice;  Fouret, Gilles;  Lecomte, Jerome;  Cortade, Fabienne;  Pessemesse, Laurence;  Baati, Narjes;  Coudray, Charles;  Lin, Ligen;  Tong, Qiang;  Wrutniak-Cabello, Chantal;  Casas, Francois;  Feillet-Coudray, Christine
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Sirt3 isoforms  Mitochondria  Cardiolipin  Phospholipids  Skeletal muscle  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
View  |  Adobe PDF(2014Kb)  |  Favorite  |  View/Download:100/7  |  Submit date:2018/10/30
Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3  
A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Chen, Shao-Ru;  Dai, Yan;  Zhao, Jing;  Lin, Ligen;  Wang, Yitao;  Wang, Ying
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Tripterygium Wilfordii Hook f  Triptolide  Celastrol  Mechanisms Of Action  Structure-activity-relationship  
Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells Journal article
SCIENTIFIC REPORTS, 2018,Volume: 8
Authors:  Wu, Chuanhong;  Zhao, Wenwen;  Yu, Jie;  Li, Shaojing;  Lin, Ligen;  Chen, Xiuping
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
View  |  Adobe PDF(1410Kb)  |  Favorite  |  View/Download:101/2  |  Submit date:2018/10/30
Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-β-Smad signaling pathway Journal article
Toxicology and Applied Pharmacology, 2018,Volume: 341,Page: 38
Authors:  Fayang Zhou;  Anqi Wang;  Dan li;  Yitao Wang;  Ligen Lin
Favorite  |  View/Download:7/0  |  Submit date:2018/10/31
Hepatic Stellate Cells  Liver Fibrosis  Penthorum Chinense Pursh  Pinocembrin  Silent Mating Type Information Regulation 2 Homolog 3  Sma- And Mad-related Proteins