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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite  |  View/Download:14/0  |  Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite  |  View/Download:8/0  |  Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
Novel biflavonoids from Cephalotaxus oliveri Mast Journal article
PHYTOCHEMISTRY LETTERS, 2018,Volume: 24,Page: 150-153
Authors:  Ren, Dai;  Meng, Fan-Cheng;  Liu, Hui;  Xiao, Tong;  Lu, Jin-Jian;  Lin, Li-Gen;  Chen, Xiu-Ping;  Zhang, Qing-Wen
Favorite  |  View/Download:29/0  |  Submit date:2018/10/30
Cephalotaxus Oliveri  Biflavonoid  Flavonoid  Alkaloid  Umcephabiflovin  Alpha-glucosidase Inhibitory Effect  
Real-time detection of oxalyl chloride based on a long-lived iridium(III) probe Journal article
DALTON TRANSACTIONS, 2017,Volume: 46,Issue: 48,Page: 17074-17079
Authors:  Wu, Chun;  Li, Guodong;  Han, Quan-Bin;  Pei, Ren-Jun;  Liu, Jin-Biao;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite  |  View/Download:19/0  |  Submit date:2018/10/30
Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells Journal article
Phytomedicine, 2016,Volume: 23,Issue: 9,Page: 939
Authors:  Ren G.;  Luo W.;  Sun W.;  Niu Y.;  Ma D.-L.;  Leung C.-H.;  Wang Y.;  Lu J.-J.;  Chen X.
Favorite  |  View/Download:11/0  |  Submit date:2018/10/31
Autophagy  Dna Damage  Nox4  Psoralidin  Ros  
Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells Journal article
Journal of Natural Medicines, 2015,Volume: 69,Issue: 4,Page: 522-530
Authors:  Ren G.;  Sha T.;  Guo J.;  Li W.;  Lu J.;  Chen X.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/28
Autophagy  Breast Cancer  Cucurbitacin b  Dna Damage  Ros  
Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in leukemia K562 cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2014,Volume: 14,Issue: 8,Page: 1146-1153
Authors:  Guo J.;  Zhao W.;  Hao W.;  Ren G.;  Lu J.;  Chen X.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/28
Apoptosis  Cancer  Cucurbitacin b  Dna Damage  G2/m Arrest  Ros