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Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2
Journal article
Journal of Pharmacology and Experimental Therapeutics, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:
Rostam M.A.
;
Shajimoon A.
;
Kamato D.
;
Mitra P.
;
Piva T.J.
;
Getachew R.
;
Cao Y.
;
Zheng W.
;
Osman N.
;
Little P.J.
Favorite
|
View/Download:7/0
|
TC[WOS]:
16
TC[Scopus]:
15
|
Submit date:2018/12/21
Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response
Journal article
Journal of Pharmacy and Pharmacology, 2016,Volume: 68,Issue: 3,Page: 368-378
Authors:
Bernard R.
;
Getachew R.
;
Kamato D.
;
Thach L.
;
Osman N.
;
Chan V.
;
Zheng W.
;
Little P.J.
Favorite
|
View/Download:6/0
|
TC[WOS]:
6
TC[Scopus]:
7
|
Submit date:2018/12/21
cell signalling
GAG hyperelongation
platelet derived growth factor
proteoglycan
tinibs
transforming growth factor-β
Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes
Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 1,Page: 110-119
Authors:
Kamato D.
;
Thach L.
;
Getachew R.
;
Burch M.
;
Hollenberg M.D.
;
Zheng W.
;
Little P.J.
;
Osman N.
Favorite
|
View/Download:6/0
|
TC[WOS]:
23
TC[Scopus]:
23
|
Submit date:2018/12/21
Glycosaminoglycan enzymes
Smad linker region
Thrombin
Transactivation-dependent
Transforming growth factor β
Transforming growth factor β-mediated site-specific Smad linker region phosphorylation in vascular endothelial cells
Journal article
The Journal of pharmacy and pharmacology, 2014,Volume: 66,Issue: 12,Page: 1722-1733
Authors:
Kamato D.
;
Rostam M.A.
;
Piva T.J.
;
Babaahmadi Rezaei H.
;
Getachew R.
;
Thach L.
;
Bernard R.
;
Zheng W.
;
Little P.J.
;
Osman N.
Favorite
|
View/Download:11/0
|
TC[WOS]:
20
TC[Scopus]:
21
|
Submit date:2018/12/21
cell signalling
serine/threonine kinase
Smad linker region
Smads
transforming growth factor-β
(S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells
Journal article
Journal of Pharmacy and Pharmacology, 2013,Volume: 65,Issue: 7,Page: 1026-1036
Authors:
Kamato D.
;
Babaahmadi Rezaei H.
;
Getachew R.
;
Thach L.
;
Guidone D.
;
Osman N.
;
Roufogalis B.
;
Duke C.C.
;
Tran V.H.
;
Zheng W.
;
Little P.J.
Favorite
|
View/Download:7/0
|
TC[WOS]:
23
TC[Scopus]:
22
|
Submit date:2018/12/21
(S)-[6]-Gingerol
biglycan
proteoglycans
Smad signalling
Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and glycosaminoglycan hyperelongation in human vascular smooth muscle cells
Journal article
Journal of Pharmacy and Pharmacology, 2013,Volume: 65,Issue: 7,Page: 1055-1063
Authors:
Little P.J.
;
Rostam M.A.
;
Piva T.J.
;
Getachew R.
;
Kamato D.
;
Guidone D.
;
Ballinger M.L.
;
Zheng W.
;
Osman N.
Favorite
|
View/Download:7/0
|
TC[WOS]:
13
TC[Scopus]:
13
|
Submit date:2018/12/21
atherosclerosis
biglycan
imatinib
PDGFβ receptor kinase activity
PDGFβ receptor phosphorylation
TGF-β stimulates biglycan core protein synthesis but not glycosaminoglycan chain elongation via Akt phosphorylation in vascular smooth muscle
Journal article
Growth Factors, 2011,Volume: 29,Issue: 5,Page: 203-210
Authors:
Osman N.
;
Getachew R.
;
Burch M.
;
Lancaster G.
;
Wang R.
;
Wang H.
;
Zheng W.
;
Little P.J.
Favorite
|
View/Download:5/0
|
TC[WOS]:
19
TC[Scopus]:
18
|
Submit date:2018/12/21
Akt
Atherosclerosis
Biglycan
Transforming growth factor-β