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Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2 Journal article
Journal of Pharmacology and Experimental Therapeutics, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam M.A.;  Shajimoon A.;  Kamato D.;  Mitra P.;  Piva T.J.;  Getachew R.;  Cao Y.;  Zheng W.;  Osman N.;  Little P.J.
Favorite | View/Download:7/0 | TC[WOS]:16 TC[Scopus]:15 | Submit date:2018/12/21
Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response Journal article
Journal of Pharmacy and Pharmacology, 2016,Volume: 68,Issue: 3,Page: 368-378
Authors:  Bernard R.;  Getachew R.;  Kamato D.;  Thach L.;  Osman N.;  Chan V.;  Zheng W.;  Little P.J.
Favorite | View/Download:6/0 | TC[WOS]:6 TC[Scopus]:7 | Submit date:2018/12/21
cell signalling  GAG hyperelongation  platelet derived growth factor  proteoglycan  tinibs  transforming growth factor-β  
Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 1,Page: 110-119
Authors:  Kamato D.;  Thach L.;  Getachew R.;  Burch M.;  Hollenberg M.D.;  Zheng W.;  Little P.J.;  Osman N.
Favorite | View/Download:6/0 | TC[WOS]:23 TC[Scopus]:23 | Submit date:2018/12/21
Glycosaminoglycan enzymes  Smad linker region  Thrombin  Transactivation-dependent  Transforming growth factor β  
Transforming growth factor β-mediated site-specific Smad linker region phosphorylation in vascular endothelial cells Journal article
The Journal of pharmacy and pharmacology, 2014,Volume: 66,Issue: 12,Page: 1722-1733
Authors:  Kamato D.;  Rostam M.A.;  Piva T.J.;  Babaahmadi Rezaei H.;  Getachew R.;  Thach L.;  Bernard R.;  Zheng W.;  Little P.J.;  Osman N.
Favorite | View/Download:11/0 | TC[WOS]:20 TC[Scopus]:21 | Submit date:2018/12/21
cell signalling  serine/threonine kinase  Smad linker region  Smads  transforming growth factor-β  
(S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells Journal article
Journal of Pharmacy and Pharmacology, 2013,Volume: 65,Issue: 7,Page: 1026-1036
Authors:  Kamato D.;  Babaahmadi Rezaei H.;  Getachew R.;  Thach L.;  Guidone D.;  Osman N.;  Roufogalis B.;  Duke C.C.;  Tran V.H.;  Zheng W.;  Little P.J.
Favorite | View/Download:7/0 | TC[WOS]:23 TC[Scopus]:22 | Submit date:2018/12/21
(S)-[6]-Gingerol  biglycan  proteoglycans  Smad signalling  
Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and glycosaminoglycan hyperelongation in human vascular smooth muscle cells Journal article
Journal of Pharmacy and Pharmacology, 2013,Volume: 65,Issue: 7,Page: 1055-1063
Authors:  Little P.J.;  Rostam M.A.;  Piva T.J.;  Getachew R.;  Kamato D.;  Guidone D.;  Ballinger M.L.;  Zheng W.;  Osman N.
Favorite | View/Download:7/0 | TC[WOS]:13 TC[Scopus]:13 | Submit date:2018/12/21
atherosclerosis  biglycan  imatinib  PDGFβ receptor kinase activity  PDGFβ receptor phosphorylation  
TGF-β stimulates biglycan core protein synthesis but not glycosaminoglycan chain elongation via Akt phosphorylation in vascular smooth muscle Journal article
Growth Factors, 2011,Volume: 29,Issue: 5,Page: 203-210
Authors:  Osman N.;  Getachew R.;  Burch M.;  Lancaster G.;  Wang R.;  Wang H.;  Zheng W.;  Little P.J.
Favorite | View/Download:5/0 | TC[WOS]:19 TC[Scopus]:18 | Submit date:2018/12/21
Akt  Atherosclerosis  Biglycan  Transforming growth factor-β