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Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells Journal article
FOOD AND CHEMICAL TOXICOLOGY, 2019,Volume: 131
作者:  Mu-Yang Huang;  Xiao-Ming Jiang;  Yu-Lian Xu;  Luo-Wei Yuan;  Yu-Chi Chen;  Guozhen Cui;  Run-Yue Huang;  Bo Liu;  Yitao Wang;  Xiuping Chen;  Jin-Jian Lu
收藏  |  浏览/下载:4/0  |  提交时间:2019/11/22
Programmed Death Ligand-1  Platycodin d  Extracellular Release  Natural Products  Cancer  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
作者:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
收藏  |  浏览/下载:2/0  |  提交时间:2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
作者:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
浏览  |  Adobe PDF(2621Kb)  |  收藏  |  浏览/下载:281/25  |  提交时间:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
作者:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
浏览  |  Adobe PDF(3226Kb)  |  收藏  |  浏览/下载:175/23  |  提交时间:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Diethyl blechnic, a novel natural product isolated from salvia miltiorrhiza bunge, inhibits doxorubicin-induced apoptosis by inhibiting ROS and activating JNK1/2 Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
作者:  Yu J.;  Gao H.;  Wu C.;  Xu Q.-M.;  Lu J.-J.;  Chen X.
收藏  |  浏览/下载:5/0  |  提交时间:2018/12/28
Cardiotoxicity  Diethyl Blechnic  Dox  Jnk1/2  Ros  
Novel biflavonoids from Cephalotaxus oliveri Mast. Journal article
PHYTOCHEMISTRY LETTERS, 2018,Volume: 24,Page: 150-153
作者:  Ren, Dai;  Meng, Fan-Cheng;  Liu, Hui;  Xiao, Tong;  Lu, Jin-Jian;  Lin, Li-Gen;  Chen, Xiu-Ping;  Zhang, Qing-Wen
收藏  |  浏览/下载:14/0  |  提交时间:2018/10/30
Cephalotaxus Oliveri  Biflavonoid  Flavonoid  Alkaloid  Umcephabiflovin  Alpha-glucosidase Inhibitory Effect  
Recent progress in doxorubicin-induced cardiotoxicity and protective potential of natural products Journal article
PHYTOMEDICINE, 2018,Volume: 40,Page: 125-139
作者:  Yu, Jie;  Wang, Changxi;  Kong, Qi;  Wu, Xiaxia;  Lu, Jin-Jian;  Chen, Xiuping
收藏  |  浏览/下载:13/0  |  提交时间:2018/10/30
Doxorubicin  Cardiotoxicity  Natural Products  
Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer Journal article
CANCER LETTERS, 2018,Volume: 412,Page: 1-9
作者:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Guo, Xia;  Dai, Xiao-Yang;  Lu, Jia-Hong;  Chen, Xiuping;  Zhu, Hong;  Lu, Jin-Jian
收藏  |  浏览/下载:13/0  |  提交时间:2018/10/30
Cepharanthine  Autophagy  Lysosome  Dacomitinib  Nsclc  
Increased expression of IRE1α associates with the resistant mechanism of osimertinib (AZD9291)-resistant non-small cell lung cancer HCC827/OSIR cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 4,Page: 550-555
作者:  Tang Z.-H.;  Su M.-X.;  Guo X.;  Jiang X.-M.;  Jia L.;  Chen X.;  Lu J.-J.
收藏  |  浏览/下载:3/0  |  提交时间:2018/12/28
Azd9291  Egfr  Ire1α  Lune Cancer  Nsclc  Osimertinib  
2-methoxy-6-acetyl-7-methyljuglone (MAM) induces iNOS/NO-mediated DNA damage response through activation of MAPKs pathways Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 6,Page: 903-913
作者:  Niu Y.;  Yuan R.;  Gao H.;  Lu J.-J.;  Kong Q.;  Chen X.
收藏  |  浏览/下载:6/0  |  提交时间:2018/12/28
Atm/chk2  Dna Damage  Inos/no  L-arginine  Mam  Mapks