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2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells Journal article
Free Radical Biology and Medicine, 2016,Volume: 92,Page: 61-77
Authors:  Sun W.;  Bao J.;  Lin W.;  Gao H.;  Zhao W.;  Zhang Q.;  Leung C.-H.;  Ma D.-L.;  Lu J.;  Chen X.
Favorite | View/Download:12/0 | TC[WOS]:25 TC[Scopus]:0 | Submit date:2018/11/06
Apoptosis  Cancer  Mam  Necroptosis  No  Ros  
An Individual Nanocube-Based Plasmonic Biosensor for Real-Time Monitoring the Structural Switch of the Telomeric G-Quadruplex Journal article
Small, 2016,Volume: 12,Issue: 21,Page: 2913-2920
Authors:  Tian Y.;  Zhang L.;  Shen J.;  Wu L.;  He H.;  Ma D.-L.;  Leung C.-H.;  Wu W.;  Fan Q.;  Huang W.;  Wang L.
Favorite | View/Download:16/0 | TC[WOS]:24 TC[Scopus]:0 | Submit date:2018/10/30
Core-shell Nanocubes  G-quadruplex  Localized Surface Plasmon Resonance  Nanoaptasensors, Biosensors  
Total tanshinones-induced apoptosis and autophagy via reactive oxygen species in lung cancer 95D Cells Journal article
American Journal of Chinese Medicine, 2015,Volume: 43,Issue: 6,Page: 1265-1279
Authors:  Gao H.;  Sun W.;  Zhao W.;  Hao W.;  Leung C.-H.;  Lu J.;  Chen X.
Favorite | View/Download:6/0 | TC[WOS]:30 TC[Scopus]:0 | Submit date:2018/11/06
Apoptosis  Autophagy  Reactive Oxygen Species  Total Tanshinones  
Virtual screening and optimization of type II inhibitors of JAK2 from a natural product library Journal article
Chemical Communications, 2014,Volume: 50,Issue: 90,Page: 13859–14054
Authors:  Ma D.-L.;  Chan D.S.-H.;  Wei G.;  Zhong H.-J.;  Yang H.;  Leung L.T.;  Gullen E.A.;  Chiu P.;  Cheng Y.-C.;  Leung C.-H.
Favorite | View/Download:13/0 | TC[WOS]:37 TC[Scopus]:0 | Submit date:2018/10/30
A G-quadruplex-selective luminescent switch-on probe for the detection of sub-nanomolar human neutrophil elastase Journal article
RSC Advances, 2013,Volume: 3,Issue: 6,Page: 1656-1659
Authors:  Leung K.-H.;  He H.-Z.;  Ma V.P.-Y.;  Yang H.;  Chan D.S.-H.;  Leung C.-H.;  Ma D.-L.
Favorite | View/Download:6/0 | TC[WOS]:30 TC[Scopus]:0 | Submit date:2018/11/06
Structure-based design of flavone derivatives as c-myc oncogene down-regulators Journal article
European Journal of Pharmaceutical Sciences, 2013,Volume: 48,Issue: 1-2,Page: 130-141
Authors:  Yang H.;  Zhong H.-J.;  Leung K.-H.;  Chan D.S.-H.;  Ma V.P.-Y.;  Fu W.-C.;  Nanjunda R.;  Wilson W.D.;  Ma D.-L.;  Leung C.-H.
Favorite | View/Download:6/0 | TC[WOS]:12 TC[Scopus]:0 | Submit date:2018/11/06
C-myc  Flavone Derivatives  G-quadruplex Dna  Structure-based Design  
Label-free detection of sub-nanomolar lead(II) ions in aqueous solution using a metal-based luminescent switch-on probe Journal article
Biosensors and Bioelectronics, 2013,Volume: 41,Issue: 1,Page: 871-874
Authors:  He H.-Z.;  Leung K.-H.;  Yang H.;  Shiu-Hin Chan D.;  Leung C.-H.;  Zhou J.;  Bourdoncle A.;  Mergny J.-L.;  Ma D.-L.
Favorite | View/Download:5/0 | TC[WOS]:71 TC[Scopus]:0 | Submit date:2018/10/30
G-quadruplex  Iridium(Iii) Complex  Label-free Detection  Lead(Ii) Ion  Luminescent Probe  
A cyclometallated iridium(III) complex as a c-myc G-Quadruplex stabilizer and down-regulator of c-myc oncogene expression Journal article
Current Medicinal Chemistry, 2013,Volume: 20,Issue: 4,Page: 576-582
Authors:  Yang H.;  Ma V.P.-Y.;  Chan D.S.-H.;  He H.-Z.;  Leung C.-H.;  Ma D.-L.
Favorite | View/Download:7/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/10/30
C-myc  Dna  G-quadruplex  Iridium(Iii)  Metal Complex  Oncogene  Promoter  
A metal-based inhibitor of tumor necrosis factor-α Journal article
Angewandte Chemie - International Edition, 2012,Volume: 51,Issue: 36,Page: 9010
Authors:  Leung C.-H.;  Zhong H.-J.;  Yang H.;  Cheng Z.;  Chan D.S.-H.;  Ma V.P.-Y.;  Abagyan R.;  Wong C.-Y.;  Ma D.-L.
Favorite | View/Download:6/0 | TC[WOS]:136 TC[Scopus]:0 | Submit date:2018/10/30
Inhibitors  Iridium(Iii) Complexes  Metal-based Inhibitors  Protein-protein Interactions  Tumor Necrosis Factor  
Discovery of a natural product-like c-myc G-Quadruplex DNA groove-binder by molecular docking Journal article
PLoS ONE, 2012,Volume: 7,Issue: 8
Authors:  Ma D.-L.;  Chan D.S.-H.;  Fu W.-C.;  He H.-Z.;  Yang H.;  Yan S.-C.;  Leung C.-H.
Favorite | View/Download:7/0 | TC[WOS]:32 TC[Scopus]:0 | Submit date:2018/10/30