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Akt downstream of NF kappa B, MAPKs and IRF3 pathway involved in macrophage activation induced by Astragalus polysaccharide RAP Journal article
JOURNAL OF FUNCTIONAL FOODS, 2017,Volume: 39,Page: 152-159
Authors:  Li, Zhi-Peng;  Li, Li-Feng;  Zhang, Quan-Wei;  Wei, Wei;  Liu, Hong-Bing;  Sao, Wan-Rong;  Ma, Dik-Lung;  Leung, Chung-Hang;  Bian, Zhao-Xiang;  Lu, Ai-Ping;  Han, Quan-Bin
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Polysaccharide  Inflammatory  Myd88  Phosphorylation  Raw264.7  
Luteolin exerted less inhibitory effect on macrophage activation induced by Astragalus polysaccharide than by lipopolysaccharide Journal article
JOURNAL OF FUNCTIONAL FOODS, 2017,Volume: 37,Page: 618-623
Authors:  Li, Zhi-Peng;  Zhang, Quan-Wei;  Wei, Wei;  Li, Li-Feng;  Ma, Dik-Lung;  Leung, Chung-Hang;  Lu, Ai-Ping;  Bian, Zhao-Xiang;  Han, Quan-Bin
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Astragalus Polysaccharide  Luteolin  Raw264.7  Mapks  Nf-kappa b  
A natural product-like JAK2/STAT3 inhibitor induces apoptosis of malignant melanoma cells Journal article
PLOS ONE, 2017,Volume: 12,Issue: 6
Authors:  Wu, Ke-Jia;  Huang, Jie-Min;  Zhong, Hai-Jing;  Dong, Zhen-Zhen;  Vellaisamy, Kasipandi;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Chiu, Pauline;  Kwong, Daniel W. J.;  Han, Quan-Bin;  Ma, Dik-Lung;  Leung, Chung-Hang
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A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity Journal article
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2017,Volume: 1861,Issue: 2,Page: 256-263
Authors:  Kang, Tian-Shu;  Wang, Wanhe;  Zhong, Hai-Jing;  Liang, Jia-Xin;  Ko, Chung-Nga;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Ma, Dik-Lung;  Leung, Chung-Hang
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Rhodium Complex  Anticancer  Melanoma  Autotaxin  Inhibitor  
Baicalein Induces Beclin 1-and Extracellular Signal-Regulated Kinase-Dependent Autophagy in Ovarian Cancer Cells Journal article
AMERICAN JOURNAL OF CHINESE MEDICINE, 2017,Volume: 45,Issue: 1,Page: 123-136
Authors:  Wang, Ya-Fang;  Xu, Yu-Lian;  Tang, Zheng-Hai;  Li, Ting;  Zhang, Le-Le;  Chen, Xiuping;  Lu, Jia-Hong;  Leung, Chung-Hang;  Ma, Dik-Lung;  Qiang, Wen-An;  Wang, Yi-Tao;  Lu, Jin-Jian
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Baicalein  Ovarian Cancer  Autophagy  Beclin 1  Erk  
Platycodin D potentiates proliferation inhibition and apoptosis induction upon AKT inhibition via feedback blockade in non-small cell lung cancer cells Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Li T.;  Chen X.;  Chen X.;  Ma D.L.;  Leung C.H.;  Lu J.J.
Favorite  |  View/Download:11/0  |  Submit date:2018/11/06
A tutorial review for employing enzymes for the construction of G-quadruplex-based sensing platforms Journal article
Analytica Chimica Acta, 2016,Volume: 913,Page: 41-54
Authors:  Dik-Lung Ma;  Wanhe Wang;  Zhifeng Mao;  Chao Yang;  Xiu-Ping Chen;  Jin-Jian Lu;  Quan-Bin Han;  Chung-Hang Leung
Favorite  |  View/Download:5/0  |  Submit date:2019/01/07
Oligonucleotide-based Sensor  G-quadruplex  Enzyme  Sensor Construction  
2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells Journal article
Free Radical Biology and Medicine, 2016,Volume: 92,Page: 61-77
Authors:  Sun W.;  Bao J.;  Lin W.;  Gao H.;  Zhao W.;  Zhang Q.;  Leung C.-H.;  Ma D.-L.;  Lu J.;  Chen X.
Favorite  |  View/Download:11/0  |  Submit date:2018/11/06
Apoptosis  Cancer  Mam  Necroptosis  No  Ros  
TLR-4 may mediate signaling pathways of Astragalus polysaccharide RAP induced cytokine expression of RAW264.7 cells Journal article
Journal of Ethnopharmacology, 2016,Volume: 179,Page: 243-252
Authors:  Wei Wei;  Hai-Tao Xiao;  Wan-Rong Bao;  Dik-Lung Ma;  Chung-Hang Leung;  Xiao-Qiang Hand;  Chun-Hay Ko;  Clara Bik-San Lau;  Chun-Kwok WONG;  Kwok-Pui Fung;  Ping-Chung Leung;  Zhao-Xiang Bian;  Quan-Bin Han
Favorite  |  View/Download:7/0  |  Submit date:2018/10/30
Astragalus Polysaccharides  Mapks  Nf-κb  Raw264.7macrophages  
Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium(III) compounds Journal article
Oncotarget, 2016,Volume: 7,Issue: 12,Page: 13965
Authors:  Liu L.-J.;  He B.;  Miles J.A.;  Wang W.;  Mao Z.;  Che W.I.;  Lu J.-J.;  Chen X.-P.;  Wilson A.J.;  Ma D.-L.;  Leung C.-H.
Favorite  |  View/Download:7/0  |  Submit date:2018/10/30
Hdm2  Metal-based Inhibitor  P53  Protein-protein Interaction