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Alarmone Ap4A is elevated by aminoglycoside antibiotics and enhances their bactericidal activity Journal article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019,Volume: 116,Issue: 19,Page: 9578-9585
Authors:  Xia Ji;  Jin Zou;  Haibo Peng;  Anne-Sophie Stolle;  Ruiqiang Xie;  Hongjie Zhang;  Bo Peng;  John J. Mekalanos;  Jun Zheng
Favorite  |  View/Download:5/0  |  Submit date:2020/05/19
Antibiotic Action  Aminoglycoside  Kanamycin  Diadenosine  Tetraphosphate Ap4a  Alarmone  
Screening and expressing HIV-1 specific antibody fragments in Saccharomyces cerevisiae Journal article
Molecular Immunology, 2018,Volume: 103,Page: 279-285
Authors:  Wang Y.;  Shan Y.;  Gao X.;  Gong R.;  Zheng J.;  Zhang X.D.;  Zhao Q.
Favorite  |  View/Download:22/0  |  Submit date:2019/01/03
Antibody Expression  Hiv-1  Saccharomyces Cerevisiae  Yeast Display  
Studies on aminoglycoside susceptibility identify a novel function of KsgA to secure translational fidelity during antibiotic stress Journal article
Antimicrobial Agents and Chemotherapy, 2018,Volume: 62,Issue: 10
Authors:  Zou J.;  Zhang W.;  Zhang H.;  Zhang X.D.;  Peng B.;  Zheng J.
Favorite  |  View/Download:12/0  |  Submit date:2019/01/16
Acinetobacter Baumannii  Aminoglycosides  Ksga  Translational Fidelity  Virulence  
Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa Journal article
PLoS Pathogens, 2018,Volume: 14,Issue: 10
Authors:  Zhang Y.;  Faucher F.;  Zhang W.;  Wang S.;  Neville N.;  Poole K.;  Zheng J.;  Jia Z.
Favorite  |  View/Download:11/0  |  Submit date:2019/01/16
Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease Journal article
ORPHANET JOURNAL OF RARE DISEASES, 2018,Volume: 13
Authors:  Vu, Mylinh;  Li, Rong;  Baskfield, Amanda;  Lu, Billy;  Farkhondeh, Atena;  Gorshkov, Kirill;  Motabar, Omid;  Beers, Jeanette;  Chen, Guokai;  Zou, Jizhong;  Espejo-Mojica, Angela J.;  Rodriguez-Lopez, Alexander;  Almeciga-Diaz, Carlos J.;  Barrera, Luis A.;  Jiang, Xuntian;  Ory, Daniel S.;  Marugan, Juan J.;  Zheng, Wei
Favorite  |  View/Download:52/0  |  Submit date:2018/10/30
Tay-sachs Disease  Induced Pluripotent Stem Cells  Neural Stem Cells  Cyclodextrin  Hp Beta Cd  Delta-tocopherol  Enzyme Replacement Therapy  Hexosaminidase a  Gm2 Gangliosidosis  High Throughput Screening  Drug Discovery  
Toward Secure Image Denoising: A Machine Learning Based Realization Conference paper
ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings, Calgary, CANADA, APR 15-20, 2018
Authors:  Zheng Y.;  Wang C.;  Zhou J.
Favorite  |  View/Download:13/0  |  Submit date:2018/12/22
Cloud Computing  Image Denoising  Machine Learning  Neural Network  Privacy  
Universal corneal epithelial-like cells derived from human embryonic stem cells for cellularization of a corneal scaffold Journal article
Translational Vision Science and Technology, 2018,Volume: 7,Issue: 5
Authors:  Yang J.;  Park J.W.;  Zheng D.;  Xu R.-H.
Favorite  |  View/Download:13/0  |  Submit date:2018/12/20
B2m Knockout  Corneal Epithelial Cells  Decellularized Cornea  Differentiation  Human Embryonic Stem Cells  Immunogenicity  
Demonstrating the potential of using transcutaneous oxygen and carbon dioxide tensions to assess the risk of pressure injuries Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 11,Page: 1466-1471
Authors:  Xue M.;  Wang D.;  Zhang Z.;  Cao Z.;  Luo Z.;  Zheng Y.;  Lu J.;  Zhao Q.;  Zhang X.D.
Favorite  |  View/Download:19/0  |  Submit date:2018/12/21
Braden Score  Pressure Injury  Transcutaneous Carbon Dioxide Tension  Transcutaneous Oxygen Tension  
A rare variant in MLKL confers susceptibility to ApoE ɛ4-negative Alzheimer's disease in Hong Kong Chinese population Journal article
Neurobiology of Aging, 2018,Volume: 68,Page: 160.e1-160.e7
Authors:  Wang B.;  Bao S.;  Zhang Z.;  Zhou X.;  Wang J.;  Fan Y.;  Zhang Y.;  Li Y.;  Chen L.;  Jia Y.;  Li J.;  Li M.;  Zheng W.;  Mu N.;  Wang L.;  Yu Z.;  Wong D.S.M.;  Zhang Y.;  Kwan J.;  Ka-Fung Mak H.;  Ambalavanan A.;  Zhou S.;  Cai W.;  Zheng J.;  Huang S.;  Rouleau G.A.;  Yang W.;  Rogaeva E.;  Ma X.;  St George-Hyslop P.;  Chu L.W.;  Song Y.-Q.
Favorite  |  View/Download:13/0  |  Submit date:2018/12/21
Apoe Ɛ4-negative  Late-onset Alzheimer's Disease  Mlkl  Whole Exome Sequencing  
Signalling pathways regulating galactosaminoglycan synthesis and structure in vascular smooth muscle: Implications for lipoprotein binding and atherosclerosis Journal article
PHARMACOLOGY & THERAPEUTICS, 2018,Volume: 187,Page: 88-97
Authors:  Afroz, Rizwana;  Cao, Yingnan;  Rostam, Muhamad Ashraf;  Ta, Hang;  Xu, Suowen;  Zheng, Wenhua;  Osman, Narin;  Kamato, Danielle;  Little, Peter J.
Favorite  |  View/Download:22/0  |  Submit date:2018/10/30
Atherosclerosis  Proteoglycans  Galactosaminoglycans  Signalling Pathways