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Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells Journal article
FOOD AND CHEMICAL TOXICOLOGY, 2019,Volume: 131
作者:  Mu-Yang Huang;  Xiao-Ming Jiang;  Yu-Lian Xu;  Luo-Wei Yuan;  Yu-Chi Chen;  Guozhen Cui;  Run-Yue Huang;  Bo Liu;  Yitao Wang;  Xiuping Chen;  Jin-Jian Lu
收藏  |  浏览/下载:4/0  |  提交时间:2019/11/22
Programmed Death Ligand-1  Platycodin d  Extracellular Release  Natural Products  Cancer  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
作者:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
收藏  |  浏览/下载:2/0  |  提交时间:2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
作者:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
浏览  |  Adobe PDF(2621Kb)  |  收藏  |  浏览/下载:281/25  |  提交时间:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
MLKL mediates apoptosis via a mutual regulation with PERK/eIF2 alpha pathway in response to reactive oxygen species generation Journal article
APOPTOSIS, 2018,Volume: 23,Issue: 9-10,Page: 521-531
作者:  Wen‑Xiang Cao;  Ting Li;  Zheng‑Hai Tang;  Le‑Le Zhang;  Zhao‑Yu Wang;  Xia Guo;  Min‑Xia Su;  Xiuping Chen;  Jin‑Jian Lu
收藏  |  浏览/下载:0/0  |  提交时间:2020/01/09
Mlkl  Eif2α  Ros  Apoptosis  Chelerythrine  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
作者:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
浏览  |  Adobe PDF(3226Kb)  |  收藏  |  浏览/下载:175/23  |  提交时间:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Recent progress in doxorubicin-induced cardiotoxicity and protective potential of natural products Journal article
PHYTOMEDICINE, 2018,Volume: 40,Page: 125-139
作者:  Yu, Jie;  Wang, Changxi;  Kong, Qi;  Wu, Xiaxia;  Lu, Jin-Jian;  Chen, Xiuping
收藏  |  浏览/下载:13/0  |  提交时间:2018/10/30
Doxorubicin  Cardiotoxicity  Natural Products  
Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer Journal article
CANCER LETTERS, 2018,Volume: 412,Page: 1-9
作者:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Guo, Xia;  Dai, Xiao-Yang;  Lu, Jia-Hong;  Chen, Xiuping;  Zhu, Hong;  Lu, Jin-Jian
收藏  |  浏览/下载:13/0  |  提交时间:2018/10/30
Cepharanthine  Autophagy  Lysosome  Dacomitinib  Nsclc  
Cucurbitacin B suppresses metastasis mediated by reactive oxygen species (ROS) via focal adhesion kinase (FAK) in breast cancer MDA-MB-231 cells Journal article
CHINESE JOURNAL OF NATURAL MEDICINES, 2018,Volume: 16,Issue: 1,Page: 10-19
作者:  Luo Wei-Wei;  Zhao Wen-Wen;  Lu Jin-Jian;  Wang Yi-Tao;  Chen Xiu-Ping
收藏  |  浏览/下载:19/0  |  提交时间:2018/10/30
Cucurbitacin b  Metastasis  Ros  Fak  Breast Cancer  
Baicalein protects tert-butyl hydroperoxide-induced hepatotoxicity dependent of reactive oxygen species removal Journal article
MOLECULAR MEDICINE REPORTS, 2017,Volume: 16,Issue: 6,Page: 8392-8398
作者:  Wang, Ya-Fang;  Tang, Zheng-Hai;  Li, Ting;  Xu, Xiao-Huang;  Chen, Xiuping;  Wang, Ying;  Wang, Yi-Tao;  Lu, Jin-Jian
收藏  |  浏览/下载:17/0  |  提交时间:2018/10/30
Baicalein  Liver Protection  Reactive Oxygen Species  Apoptosis  
Osimertinib (AZD9291) decreases programmed death ligand-1 in EGFR-mutated non-small cell lung cancer cells Journal article
ACTA PHARMACOLOGICA SINICA, 2017,Volume: 38,Issue: 11,Page: 1512-1520
作者:  Jiang, Xiao-Ming;  Xu, Yu-Lian;  Huang, Mu-Yang;  Zhang, Le-Le;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
收藏  |  浏览/下载:16/0  |  提交时间:2018/10/30
Non-small Cell Lung Cancer  Egfr  Osimertinib  Pd-l1  Ubiquitin-proteasome System  Mg-132  Bortezomib  Gsk3 Beta  Licl