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Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
作者:  Zihao Wang;  Ke-Gang Linghu;  Yuanjia Hu;  Huali Zuo;  Hao Yi;  Shi-Hang Xiong;  Jinjian Lu;  Ging Chan;  Hua Yu;  Run-Yue Huang
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/04
Rheumatoid Arthritis  Network Pharmacology  Traditional Chinese Medicine  Huayu-qiangshen-tongbi Formula  In Vitro Validation  
Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells Journal article
FOOD AND CHEMICAL TOXICOLOGY, 2019,Volume: 131
作者:  Mu-Yang Huang;  Xiao-Ming Jiang;  Yu-Lian Xu;  Luo-Wei Yuan;  Yu-Chi Chen;  Guozhen Cui;  Run-Yue Huang;  Bo Liu;  Yitao Wang;  Xiuping Chen;  Jin-Jian Lu
收藏  |  浏览/下载:4/0  |  提交时间:2019/11/22
Programmed Death Ligand-1  Platycodin d  Extracellular Release  Natural Products  Cancer  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
作者:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
收藏  |  浏览/下载:2/0  |  提交时间:2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
Inhibition of lung cancer by 2-methoxy-6-acetyl-7-methyljuglone (MAM) through induction of necroptosis by targeting receptor-interacting protein 1 (RIP1) Journal article
Antioxidants & Redox Signaling, 2018,Volume: 0,Issue: JA
作者:  Sun W;  Yu J;  Gao H;  Wu X;  Wang S;  Hou Y;  Lu JJ;  Chen X
收藏  |  浏览/下载:6/0  |  提交时间:2019/01/16
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
作者:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
浏览  |  Adobe PDF(2621Kb)  |  收藏  |  浏览/下载:281/25  |  提交时间:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
A novel design of a polynuclear co-delivery system for safe and efficient cancer therapy Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 63,Page: 8737-8740
作者:  Xing, Lei;  Zhang, Jia-Liang;  Zhou, Tian-Jiao;  He, Yu-Jing;  Cui, Peng-Fei;  Gong, Jia-Hui;  Sun, Minjie;  Lu, Jin-Jian;  Huang, Zhangjian;  Jin, Liang;  Jiang, Hu-Lin
收藏  |  浏览/下载:15/0  |  提交时间:2018/10/30
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
作者:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
浏览  |  Adobe PDF(3226Kb)  |  收藏  |  浏览/下载:175/23  |  提交时间:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Anticancer drug discovery from Chinese medicinal herbs Journal article
CHINESE MEDICINE, 2018,Volume: 13
作者:  Huang, Mu-Yang;  Zhang, Le-Le;  Ding, Jian;  Lu, Jin-Jian
收藏  |  浏览/下载:61/0  |  提交时间:2018/10/30
Chinese Medicinal Herbs  Anticancer  Drug Discovery  Natural Products  Formulae  
Targeting the Hsp90-Cdc37-client protein interaction to disrupt Hsp90 chaperone machinery Journal article
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2018,Volume: 11
作者:  Li, Ting;  Jiang, Hu-Lin;  Tong, Yun-Guang;  Lu, Jin-Jian
收藏  |  浏览/下载:16/0  |  提交时间:2018/10/30
Hsp90 Chaperone Machinery  Cdc37  Kinase Client  Protein Interaction  
Novel biflavonoids from Cephalotaxus oliveri Mast. Journal article
PHYTOCHEMISTRY LETTERS, 2018,Volume: 24,Page: 150-153
作者:  Ren, Dai;  Meng, Fan-Cheng;  Liu, Hui;  Xiao, Tong;  Lu, Jin-Jian;  Lin, Li-Gen;  Chen, Xiu-Ping;  Zhang, Qing-Wen
收藏  |  浏览/下载:14/0  |  提交时间:2018/10/30
Cephalotaxus Oliveri  Biflavonoid  Flavonoid  Alkaloid  Umcephabiflovin  Alpha-glucosidase Inhibitory Effect