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Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Zihao Wang;  Ke-Gang Linghu;  Yuanjia Hu;  Huali Zuo;  Hao Yi;  Shi-Hang Xiong;  Jinjian Lu;  Ging Chan;  Hua Yu;  Run-Yue Huang
Favorite  |  View/Download:6/0  |  Submit date:2019/12/04
Rheumatoid Arthritis  Network Pharmacology  Traditional Chinese Medicine  Huayu-qiangshen-tongbi Formula  In Vitro Validation  
Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells Journal article
FOOD AND CHEMICAL TOXICOLOGY, 2019,Volume: 131
Authors:  Mu-Yang Huang;  Xiao-Ming Jiang;  Yu-Lian Xu;  Luo-Wei Yuan;  Yu-Chi Chen;  Guozhen Cui;  Run-Yue Huang;  Bo Liu;  Yitao Wang;  Xiuping Chen;  Jin-Jian Lu
Favorite  |  View/Download:9/0  |  Submit date:2019/11/22
Programmed Death Ligand-1  Platycodin d  Extracellular Release  Natural Products  Cancer  
γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
Toxicology and Applied Pharmacology, 2019,Volume: 363,Page: 142-153
Authors:  Wang A.;  Zhou F.;  Li D.;  Lu J.-J.;  Wang Y.;  Lin L.
Favorite  |  View/Download:11/0  |  Submit date:2018/12/28
Fibrogenesis  Hmgb1  Liver Fibrosis  Sirtuin 3  Superoxide  Γ-mangostin  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
Authors:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
Favorite  |  View/Download:6/0  |  Submit date:2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:431/30  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
A novel design of a polynuclear co-delivery system for safe and efficient cancer therapy Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 63,Page: 8737-8740
Authors:  Xing, Lei;  Zhang, Jia-Liang;  Zhou, Tian-Jiao;  He, Yu-Jing;  Cui, Peng-Fei;  Gong, Jia-Hui;  Sun, Minjie;  Lu, Jin-Jian;  Huang, Zhangjian;  Jin, Liang;  Jiang, Hu-Lin
Favorite  |  View/Download:16/0  |  Submit date:2018/10/30
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(3226Kb)  |  Favorite  |  View/Download:254/23  |  Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Anticancer drug discovery from Chinese medicinal herbs Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Huang, Mu-Yang;  Zhang, Le-Le;  Ding, Jian;  Lu, Jin-Jian
Favorite  |  View/Download:63/0  |  Submit date:2018/10/30
Chinese Medicinal Herbs  Anticancer  Drug Discovery  Natural Products  Formulae  
Targeting the Hsp90-Cdc37-client protein interaction to disrupt Hsp90 chaperone machinery Journal article
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2018,Volume: 11
Authors:  Li, Ting;  Jiang, Hu-Lin;  Tong, Yun-Guang;  Lu, Jin-Jian
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
Hsp90 Chaperone Machinery  Cdc37  Kinase Client  Protein Interaction  
Novel biflavonoids from Cephalotaxus oliveri Mast. Journal article
PHYTOCHEMISTRY LETTERS, 2018,Volume: 24,Page: 150-153
Authors:  Ren, Dai;  Meng, Fan-Cheng;  Liu, Hui;  Xiao, Tong;  Lu, Jin-Jian;  Lin, Li-Gen;  Chen, Xiu-Ping;  Zhang, Qing-Wen
Favorite  |  View/Download:15/0  |  Submit date:2018/10/30
Cephalotaxus Oliveri  Biflavonoid  Flavonoid  Alkaloid  Umcephabiflovin  Alpha-glucosidase Inhibitory Effect